Estenose Aórtica de Baixo Gradiente

Electrochemical Gradient

A.p bio 🧪 UNIT 1 CHEMISTRY OF LIFE — TEST CRAM Q&A 🟣 TOPIC 1: BIOLOGY REVIEW & STATISTICS Experimental Design Q: What is the independent variable? A: The variable the scientist changes/manipulates. Q: What is the dependent variable? A: The variable that is measured/observed. Q: Easy way to remember independent vs. dependent? A: Independent = I change it. Dependent = data I collect. Q: In an experiment, fertilizer concentration is changed and plant height is measured. What is the independent variable? A: Fertilizer concentration. Q: What is the dependent variable? A: Plant height. Q: What are constants? A: Things kept the same for every experimental group. Q: What is a control group? A: A group used as a comparison/baseline. Q: What is a positive control? A: A group that should produce a known positive result. Q: What is a negative control? A: A group that should produce no response/result. ⸻ Data & Statistics Q: What is qualitative data? A: Descriptive data that isn’t measured numerically. Example: color, texture, smell. Q: What is quantitative data? A: Numerical/measurable data. Example: 15 cm, 20°C, 5 grams. Q: What is the mean? A: The average: add all values and divide by the number of values. Q: What is the median? A: The middle value when data is arranged from least to greatest. Q: What is the mode? A: The value that occurs most often. Q: What is the range? A: Highest − lowest. Q: What does standard deviation tell you? A: How spread out the data is around the mean. Q: Small standard deviation means what? A: Data points are close together/consistent. Q: Large standard deviation means what? A: Data points are more spread out/variable. Q: If Group A and Group B have similar means, but Group A has a much smaller standard deviation, what does that mean? A: Group A’s data is more consistent and clustered around the mean. Q: What is SEM? A: Standard error of the mean; it estimates how accurately the sample mean represents the population mean. Q: What does a small SEM mean? A: The mean is more precise/reliable. Q: What do error bars show? A: The amount of variation or uncertainty around a mean, depending on what the graph specifies. Q: What should you look for when reading graphs? A: Specific data points, trends, patterns, increases/decreases, and relationships between variables. ⸻ 💧 TOPIC 2: STRUCTURE OF WATER & HYDROGEN BONDING Q: Why is water polar? A: Oxygen is more electronegative than hydrogen, so oxygen becomes partially negative and hydrogen becomes partially positive. Q: What does δ− mean? A: Partial negative charge. Q: What does δ+ mean? A: Partial positive charge. Q: What type of bond holds the H and O together inside one water molecule? A: Covalent bond. Q: What type of attraction occurs between different water molecules? A: Hydrogen bonds. Q: What causes water’s cohesion? A: Hydrogen bonding between water molecules. Q: What is cohesion? A: Water molecules sticking to other water molecules. Q: What is adhesion? A: Water sticking to other surfaces/materials. Q: What causes surface tension? A: Cohesion/hydrogen bonding between water molecules at the surface. Q: What is capillary action? A: Water moving upward through a narrow space because of cohesion + adhesion. Q: Why can water move upward through plants? A: Hydrogen bonding creates cohesion between water molecules, while adhesion helps water interact with the plant’s xylem walls, allowing capillary action. Q: Which interaction is primarily responsible for water cohesion? A: Hydrogen bonds. Q: What is a solute? A: The substance being dissolved. Q: What is a solvent? A: The substance that does the dissolving. Q: What is a solution? A: A solute + solvent mixture. ⭐ MUST KNOW: Polarity → hydrogen bonding → cohesion/adhesion → capillary action → water movement in plants ⸻ 🧬 TOPIC 2: ELEMENTS OF LIFE Q: Why is carbon so important to life? A: Carbon has 4 valence electrons, allowing it to form four stable covalent bonds and create many different structures. Q: Why can carbon create such a huge diversity of molecules? A: It can bond with itself and many other elements, creating chains, rings, branches, and complex structures. Q: What four major macromolecules are built from carbon? A: Carbohydrates, proteins, lipids, and nucleic acids. Q: What element is especially important in amino acids and nitrogenous bases? A: Nitrogen. Q: What element is found in nucleic acids and certain lipids? A: Phosphorus. Functional Groups Q: What is a functional group? A: A group of atoms that gives an organic molecule specific chemical properties and behaviors. Q: What are the major functional groups you need to know? A: Hydroxyl, carbonyl, carboxyl, amino, and phosphate. Q: What is a hydroxyl group? A: –OH Q: What is a carboxyl group? A: –COOH Q: What is an amino group? A: –NH₂ Q: What is a phosphate group? A: –PO₄ group. Q: What is a carbonyl group? A: A carbon double-bonded to oxygen: C=O. Q: What is a hydrocarbon? A: A molecule made only of carbon and hydrogen. ⸻ 🔗 TOPIC 3: INTRODUCTION TO BIOLOGICAL MACROMOLECULES Q: What is a monomer? A: A small building block that can join with others. Q: What is a polymer? A: A large molecule made from repeating monomers. Q: What are the four major biological macromolecules? A: Carbohydrates, proteins, lipids, nucleic acids. Q: What is dehydration synthesis? A: A process that joins monomers by forming a covalent bond and removing H₂O. Q: What is hydrolysis? A: A process that breaks covalent bonds by adding H₂O. 🧠 REMEMBER: Dehydration = take water OUT → build Hydrolysis = add water → break Q: Which process joins monomers to form a polymer? A: Dehydration synthesis. Q: Which process breaks polymers apart? A: Hydrolysis. Q: What happens to water during dehydration synthesis? A: Water is removed/released. Q: What happens to water during hydrolysis? A: Water is added. ⸻ 🍞 TOPIC 4: PROPERTIES OF BIOLOGICAL MACROMOLECULES Carbohydrates Q: What is a monosaccharide? A: A single sugar monomer. Q: What is a polysaccharide? A: A carbohydrate polymer made of many sugar units. Q: What is starch used for? A: Energy storage in plants. Q: What is glycogen used for? A: Energy storage in animals. Q: What is cellulose used for? A: Structural support in plant cell walls. ⸻ Proteins Q: What are proteins made of? A: Amino acids. Q: What is the monomer of a protein? A: Amino acid. Q: What part of an amino acid varies between amino acids? A: The R group. Q: Why are R groups important? A: Their different properties affect how a protein folds and functions. ⸻ Lipids Q: Are lipids generally polar or nonpolar? A: Mostly nonpolar/hydrophobic. Q: What does hydrophobic mean? A: Water-fearing; doesn’t mix well with water. Q: What does hydrophilic mean? A: Water-loving; interacts with water. Q: What is the difference between saturated and unsaturated fatty acids? A: Saturated = no C=C double bonds. Unsaturated = one or more C=C double bonds. Q: Which fatty acid has more bends/kinks? A: Unsaturated fatty acid. Q: Why do unsaturated fatty acids have kinks? A: Their double bonds bend the carbon chain. ⸻ Phospholipids Q: What two types of regions does a phospholipid have? A: A polar hydrophilic head and nonpolar hydrophobic tails. Q: Why are phospholipids important in cells? A: They form the cell membrane bilayer. Q: Why do phospholipids form a bilayer? A: The hydrophilic heads face the watery environments while the hydrophobic tails face inward away from water. ⸻ Nucleic Acids Q: What do nucleic acids do? A: They store and transmit biological information. Q: What is the monomer of nucleic acids? A: Nucleotide. Q: What are nucleotides made of? A: A 5-carbon sugar + phosphate group + nitrogenous base. ⸻ 🧩 TOPIC 5: STRUCTURE & FUNCTION OF BIOLOGICAL MACROMOLECULES Protein Structure Q: What determines a protein’s primary structure? A: The sequence of amino acids. Q: What is secondary protein structure? A: Local folding into structures such as alpha helices and beta sheets, stabilized by hydrogen bonds. Q: What is tertiary structure? A: The overall 3D shape of one polypeptide. Q: What is quaternary structure? A: Multiple polypeptide chains/subunits working together. ⭐ KNOW THIS ORDER: Primary → Secondary → Tertiary → Quaternary Q: Why can changing one amino acid affect protein function? A: It can change interactions between amino acids, which can change the protein’s shape, potentially changing its function. Q: What is denaturation? A: When a protein loses its normal shape, causing it to lose or reduce its function. Q: What can cause protein denaturation? A: Things such as high temperature or extreme pH. ⸻ DNA Structure Q: What does antiparallel mean? A: The two DNA strands run in opposite directions: one 5’ → 3’ and the other 3’ → 5’. Q: Why is DNA directionality important? A: DNA strands have specific 5’ and 3’ ends, which determines how they are read and copied. ⸻ Carbohydrate Structure Q: Why can two carbohydrates made from similar sugar monomers have different functions? A: Their monomers can have different arrangements, bonding, branching, and structures, which changes their properties and functions. Q: Example of this? A: Starch and cellulose are both made from glucose, but their different bonding/arrangements give them different functions. ⸻ 🧬 TOPIC 6: NUCLEIC ACIDS Q: What are the three parts of a nucleotide? A: 5-carbon sugar + phosphate group + nitrogenous base. Q: What sugar is found in DNA? A: Deoxyribose. Q: What sugar is found in RNA? A: Ribose. Q: What nitrogenous base is found in DNA but not RNA? A: Thymine (T). Q: What nitrogenous base is found in RNA instead of thymine? A: Uracil (U). Q: Is DNA usually single- or double-stranded? A: Double-stranded. Q: Is RNA usually single- or double-stranded? A: Single-stranded. Q: What does DNA store? A: Genetic/biological information. Q: What connects nucleotides together? A: Covalent bonds form the sugar-phosphate backbone. ⸻ 🧬 Base Pairing Q: What does A pair with in DNA? A: T Q: What does T pair with? A: A Q: What does C pair with? A: G Q: What does G pair with? A: C RNA: A ↔ U C ↔ G Q: If one DNA strand is 5’-ACGTAC-3’, what is the complementary strand? A: 3’-TGCATG-5’ Q: Why is it written 3’ → 5’? A: Because DNA strands are antiparallel. ⸻ 🔥 UNIT 1 BIG CONNECTIONS — YOUR TEACHER WILL LOVE THESE Q: Explain the water connection. A: Water’s polarity causes hydrogen bonding, which produces properties like cohesion and adhesion that are important for biological functions such as water movement through plants. Q: Explain the carbon connection. A: Carbon’s four valence electrons allow it to form many covalent bonds, creating the huge diversity of biological molecules. Q: Explain the macromolecule connection. A: Monomers join → polymers/macromolecules form → their structure determines their properties and function. Q: Explain the protein connection. A: Amino acid sequence → protein shape → protein function. Q: Explain the DNA connection. A: Nucleotide sequence → biological/genetic information. Q: Explain the experiment connection. A: Experimental design → data → analysis → evidence → biological conclusion. ⸻ 🚨 15 QUESTIONS YOU SHOULD BE ABLE TO ANSWER WITHOUT LOOKING What is the independent variable?     → What you change. What is the dependent variable?     → What you measure. Small standard deviation means…?     → Data is consistent/close together. Why is water polar?     → Oxygen is more electronegative than hydrogen. What causes cohesion?     → Hydrogen bonding. What causes capillary action?     → Cohesion + adhesion. Why is carbon so versatile?     → Four valence electrons. What joins monomers?     → Dehydration synthesis. What breaks polymers?     → Hydrolysis. Protein monomer?     → Amino acid. Nucleic acid monomer?     → Nucleotide. Unsaturated fatty acids have what?     → Double bonds and kinks. What determines protein shape?     → Amino acid sequence/interactions. DNA sugar/base?     → Deoxyribose + thymine. DNA strands are…?     → Double-stranded and antiparallel. 🧠 LAST-MINUTE MEMORY CHAIN Memorize this exact chain: Water: POLAR → H-BONDS → COHESION/ADHESION → CAPILLARY ACTION Macromolecules: MONOMER → DEHYDRATION → POLYMER Breaking: POLYMER → HYDROLYSIS → MONOMERS Protein: AMINO ACID SEQUENCE → SHAPE → FUNCTION DNA: NUCLEOTIDE SEQUENCE → INFORMATION Experiment: INDEPENDENT → DEPENDENT → DATA → EVIDENCE → CONCLUSION

Art of interviewing In an interview, what factor do we need to consider? Social Economic Cultural How does the provider pick up on subtle ques? Shifts in body language in addition to spoken word Patients will tell you what is wrong with them if you ask the right questions Questions Open Ended OLDCARTS Don't use medical jargon Confrontation Watch for subtle ques "You look upset discussing _____, lets talk about it" Points out something striking about the patient's behavior or statement ○ Directs the patient's attention to something of which they may or may not be aware of ○ You look upset, you sound uncomfortable about that, Is there a reason you look away from me as you speak What does good communication improve? Health outcomes by resolving symptoms and reducing patient's psychogical distress and anxiety 85% of all malpractice lawsuits are based on poor communication skills What should we implement during an interview? ACTIVE LISTENING Watch their body language, tone, eye contact, speech and spoken word Understanding of what is being said, body language and other non verbal ques Symptom SUBJECTIVE ~What the patient feels ~Described by the patient Can be influenced by culture, intelligence and socioeconomic background Constitutional Symptom Fevers, Chills, Weight Gain, Weight Loss Effect all symptoms Sign OBJECTIVE What the observer finds on the assessment Crackles, dry skin, bruising What are the basic interviewing techniques? Questions Silence Facilitation Confrontation Interpretation Reflection Support Transitions Silence Silence is ok, but limit to 2 minutes or less If a patient is silent, you are silent Can restart the conversation with, "What are you thinking about?" Should never be used with the overtalkative patients ○ Can indicate interest and support ○ Don't allow more than 2 minutes of silence ○ Ok to ask: What are you thinking about? You were saying? These things are hard to think about Facilitation Keeps the conversation going "Tell me more about..." Encourages a patient to continue talking without controlling the direction of the conversation ○ Verbal and nonverbal communication that encourages the patient to keep talking ○ Go on, Tell me more, uh huh, And then Interpretation Based on inference "It sounds as if you are afraid...." Based on inference rather than observation ○ The provider interprets the patient's behavior, encouraging the patient to observe their own role in the problem. ○ You seem happy about that, Are you afraid you've done something wrong?, I wonder if your ____ is related to _____ Reflection Repeat part of the statement made by the patient Pt: "I haven't worked since 2016" APRN: "You haven't worked since 2016? Lets talk about that" A response that mirrors what the patient has just expressed ○ Patient: I am nervous about starting a new medication ■ Provider: Nervous about starting a new medication? Support Build a trusting relationship with the patient by using reassurance and empathy Shows an interest in or understanding of a patient ○ I understand ■ Reassurance ● A response that conveys to the patient that the interviewer understands what has been talked about ● That's great you were able to stop smoking, I am glad you came in today - we are going to help you ■ Empathy ● Response that recognizes a patient's feelings and does not criticize ● It's an understand, not an emotional state of sympathy ● I know it is not easy ______, I'm sure ______ has caused you a large amount of anxiety Transitions "Now I am going to ask you questions about..." Used as guides to allow the patient to better understand the logic of the interviewers questions in order to have a good flow to change the topic ○ I am now going to ask you questions about ______, Now let's talk about______ What does a past medical hx all include? General state of overall health Past Illnesses Hospitalizations Surgeries Prior injuries and accidents Allergies Current Medications Diet Sleep Patterns Immunizations Substance Abuse Complementary / Alternative Therapies What is sensitivity? How good a test is at identifying people who truly have the disease True Positive - Positive results are convincing RULE OUT = SnNout Sensitive test + Negative = disease OUT What is specificity How well a test does at correctly identifying people who are well True Negative - negative result is convincing RULE IN = SpPin Specific test + Positive = disease IN What is a functional capacity assessment? Asses geriatric patients abilities to perform activities of daily living (ADLs) -Self Care -Instrumental -Mobility -Timed Get Up and Go test Self Care ADLs Dressing Bathing Transferring from bed to chair Toileting Grooming Feeding oneself Instrumental ADLs Meal Preparation Managing Finances Use the phone Taking Meds Doing Housework Shopping Managing Transport Mobility ADLs Walking from room to room Climbing stairs Walking outdoors What is the timed get up and go test? Rise from chair, walk 10 feet, turn around, walk back to chair, turn and sit down Should be completed in 10 seconds or less If greater than 20 seconds, patient will need further evaluation What is the strongest predictor of future disability and death? Gait What should we be assessing in the elderly in relation to ADLs? # of falls in the last year Gender Identity One's internal sense of gender at a given time How a person feels and identifies themselves in terms of gender such as being a boy, girl or another gender Sexual Orientation The presence and/or object of a person's romantic, sexual, physical or spiritual attractions Who someone is attracted to or has romantic feeing towards ■ Same gender, different gender, more than one gender Alternative Medicine Systems Complete systems of health care that developed separately from Western/conventional medicine i. Traditional Chinese Medicine ii. Traditional Indigenous Healing Practices iii. Homeopathic Medicine Ayurvedic - translates to knowledge of life, origin = India Mind-Body Interventions Techniques that use the mind to help improve physical health and well-being Biofeedback Yoga / Meditation / Deep Breathing Prayer Tai Chi Biologically Based Therapies Natural substances or products from nature to improve health or treat illness Vitamins Herbal Products Probiotics Dietary Supplements Specialty Diets Manipulative and Body Physical movement, pressure, or hands-on techniques to help the body feel better or function better Chiropractic Osteopathy Reflexology / Massage Therapy Energy Therapies Energy fields in or around the body can be influenced to improve health or well-being Biofield therapy ~Intended to affect a patient's energy field for the purpose of healing by having a healer place their hands in or through them; the therapist's healing force restores the patient -Reiki -Therapeutic Touch Bioelectromagnetic based therapies ~Involve the unconventional use of electromagnetic fields. -Positioning external magnetic fields near or around the person, usually by placing magnets on the body, into clothing, or in mattresses Acupuncture -Traditional Chinese medicine in which thin needles are placed into the body to allow qi (energy) to flow unimpeded What is Yin & Yang? 2 opposite yet connected forces that exist in nature and the body They work together to maintain balance and harmony Yin Cooler Darker Quieter Slower Passive Associated with Rest Earth Moon Night Water Femininity Cold Yang Warmer Brighter Active Faster Masculinity Associated with Activity ■ Day, Heat, Light, Movement What is the goal of Yin & Yang? To Remain Healthy: ○ Maintaining a proper balance between yin and yang ○ Neither is considered completely good or bad ○ Both are necessary and work together What is the goal of Chinese Medicine? Not only cure disease, but keep people well Disease means failure in prevention of health care Health is a shared responsibility between the patient and provider Chinese medicine treats the patient as a whole rather than separate systems Preserving health, curing disease of mind, body and spirit The mind can help direct your body's energy toward healing and recovery Disharmony ■ Provides framework to help aid in healing ■ Ex: Patient doesn't catch the flu, develops disharmony. Abx, acupuncture or herbs can help to redevelop harmony What 2 techniques do the Chinese look at to diagnose? Tongue Pulse Assessment Tongue Assessment Believed to be a clear indicator of disharmony Color, Shape, Moisture, Coating, Thickness, Cracks & Texture of the tongue Pulse Assessment Disharmonies of the body have effects on the pulse ● Divided into 3 sections ○ Cun ■ Closest to the wrist ○ Guan ■ Second position ○ Chi ■ 3rd position, furthest from the wrist Left wrist (yin) ■ Heart, liver and kidney Right Wrist (yang) ■ Lungs, spleen and kidney Special Considerations for Peds: Head Palpable Anterior and Posterior Fontanelles Special Considerations for Peds: Eyes Inspecting for red reflex Special Considerations for Peds: Mouth Inspect for oral thrush and geographic tongue Special Considerations for Peds: Genitalia Inspect for hypospadias (males), diaper dermatitis, vaginal yeast Special Considerations for Peds: Hip Dystocia Perform Barlow and Ortolani Maneuvers Assess for normal newborn primitive reflexes Special Considerations for teens Assess Tanner Stages for breast tissue and genitals Can ask parents to step out of the room for the exam to allow you to ask further personal questions. The parents can refuse, although most are happy to step out If the parent does agree, do not continue with further examination until another medical witness is in the room with you Additional questions for teens include social history, illegal drug use, sexuality, suicide/depression screening and safety at home Billing and Coding Current Procedure Terminology (CPT) International Classification of Disease (ICD) Current Procedure Terminology (CPT) -Codes used to document many of the medical procedures performed in a medical office -Services and procedures provided 1. Evaluation and Management 2. Performance and Measurement 3.Emerging Medical Terminology International Classification of Disease (ICD) Explains the reason for the services ○ Classifies diseases and injuries and is used to track mortality and morbidity statistics ○ Assigned to identify the diagnosis, system, condition, problem, complaint or other reason for the encounter Bias An unfair or one sided opinion that can influence how someone thinks or acts Implicit Bias Unconscious attitudes or beliefs about people that can affect how we treat or judge them without realizing it Explicit Bias Conscious and intentional opinions to beliefs about a person or group that can lead to unfair treatment Race Groups of people based on physical traits, national origin and ancestry ■ Skin color, different features Ancestery ○ People, families and backgrounds one comes from ○ Genealogic history, understanding of one's genetic heritage Racial Bias An unfair or one sided opinion/judgement about someone based on their race Racism Treating someone unfairly, badly, negatively because of their race Scientific Racism The false idea that science proves some races are better, smarter or more capable than others Belief of biological evidence of racial inferiority/superiority Example: Black people are biologically different and inferior to white people Dominant Narrative The main or most widely accepted story or viewpoint about a topic, interests or ideas in a dominant social group Spirituality A person's sense of connection to something bigger than themselves, such as nature, a higher power, or their own inner beliefs and values. A person's search for meaning and purpose in life, including how they connect with themselves, others, nature, the present moment, and what they consider meaningful or sacred Religion A set of beliefs, practices, and traditions that help people understand life, spirituality, and their connection to a higher power or something sacred Gender Expression How a person shows or expresses their gender through things like clothing, hairstyle, behavior, voice or appearance What is included with Telehealth? Telemedicine Remote Patient Monitoring Videoconferencing mHealth eConsults Patient education / Coaching Continuing Education for the provider Telemedicine Patient care / Consultation Patient Monitoring Mentoring Digital Imaging What is included in Telehealth Etiquite? Environment Performance Privacy Telehealth - Environment Visual- Provider appearance Room appearance Lighting Picture quality Auditory - Provider noises, background noise, audio quality Telehealth - Performance Provider appearance and communication Use of equipment Provider Preparation Telehealth - Privacy Privacy of sites Equipment privacy settings Consents Mastered (1) You've been getting these terms right! Select this one What is the main purpose of an interview? Gather pertinent information -Patient's illness and how well they are adapting to said illness Goal is to gather important information regarding patient's illness/condition and how they are coping with it Not studied (2) You haven't studied these terms yet! Select these 2 What is included in Chinese medicine? What happens if there is a disharmony between Yin & Yang?

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Chapter 1: Major Themes of Anatomy and Physiology - Homeostasis and Gradients

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Human Anatomy and Physiology Third Edition Chapter 1 Introduction to Anatomy and Physiology Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Characteristics of Living Organisms (1 of 2) Living Organisms share distinct properties •Cellular Composition—Cells are the smallest units that carry out the functions of life •Metabolism—Living organisms carry out chemical processes collectively called metabolism –“Building” processes are known as Anabolism –“Breaking down” processes are known as Catabolism •Growth—An increase in the size and/or number of cells Loading… Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Characteristics of Living Organisms (2 of 2) Living Organisms share distinct properties (continued) •Excretion—Elimination of potentially harmful waste products created by metabolic processes •Responsiveness or Irritability—Organisms sense and react to changes or stimuli in their environment •Movement—Organisms or individual cells of an organism move •Reproduction—Production of new cells during growth or repair or reproduction of new organisms Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Levels of Structural Organization and Body Systems (1 of 7) The body is constructed of a series of progressively larger “building blocks” known as the Structural Levels of Organization •Chemical Level—This is the smallest level; Chemicals range from tiny atoms to complex molecules •Cellular Level—Groups of many different types of molecules combine in specific ways to form cellular structures •Tissue Level—Two or more cell types and material outside them, called extracellular matrix, combine to perform a common function Loading… Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Levels of Structural Organization and Body Systems (2 of 7) Structural Levels of Organization (continued) •Organ Level—Two or more tissue types combine to form an organ with a recognizable shape that performs a specialized task •Organ System Level—Two or more organs that together carry out a broad function in the body –The human body has 11 organ systems •Organism Level—The organ systems function together to make up the working human body—an organism Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Levels of Structural Organization and Body Systems (3 of 7) Figure 1.5 Six structural levels of organization of the human body. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Levels of Structural Organization and Body Systems (4 of 7) Figure 1.6 The 11 organ systems of the human body Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Levels of Structural Organization and Body Systems (5 of 7) Figure 1.6 The 11 organ systems of the human body Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Levels of Structural Organization and Body Systems (6 of 7) Figure 1.6 The 11 organ systems of the human body Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Levels of Structural Organization and Body Systems (7 of 7) Figure 1.6 The 11 organ systems of the human body Loading… Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Types of Anatomy and Physiology (1 of 2) Study of Anatomy can be approached in several ways •Systemic Anatomy—Examines individual organ systems •Regional Anatomy—Examines the body in regions, such as the head and neck •Surface Anatomy—Examines surface markings •Gross Anatomy—Examines structures that can be seen with the unaided eye •Microscopic Anatomy—Examines cells (Cytology) and tissues (Histology) with the use of a microscope Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.2 Types of Anatomy and Physiology (2 of 2) Study of Physiology includes numerous subfields •Physiology subfields are classified by organ or organ systems, such as neurophysiology and cardiophysiology •Physiologists can also study other structural levels of organization of the body such as chemical, cellular, and tissue levels Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Word Parts •The language of science is built on Word Roots—core components of words with specific meanings •Word roots are combined with Prefixes and Suffixes to yield scientific terms •For example, combine the following: –Prefix an- (means without) –Word root encephala- (means brain) –Suffix -ic (means condition of) •“Anencephalic” is the condition of lacking a part of the brain Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 The Anatomical Position and Directional Terms (1 of 4) Anatomical Position—Common frame of reference from which all body parts and regions are described regardless of position –Body is standing upright –Feet are shoulder width apart –Upper limbs at the sides of trunk –Head and palms facing forward Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 The Anatomical Position and Directional Terms (2 of 4) Directional Terms—Describe the relative locations of body parts and markings to ensure accurate communication among scientists and healthcare professionals •Anterior/Posterior—Anterior refers to the front and posterior refers to the back; Can refer to body as a whole or to a body part •Superior/Inferior—Superior, or cranial, means towards the head and inferior, or caudal, means towards the tail; Used to refer to positions on head, neck, and trunk only Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 The Anatomical Position and Directional Terms (3 of 4) Directional Terms (continued) •Proximal/Distal—Proximal means closer to the point of origin and distal means further from the point of origin; Used to refer to positions on the limbs only •Medial/Lateral—Medial refers to a position closer to the middle line of the body, called the midline, and lateral refers to a position farther away from the midline •Superficial/Deep—Superficial refers to structures closer to the surface of the body and deep refers to structures farther below Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 The Anatomical Position and Directional Terms (4 of 4) Figure 1.7 Directional terms. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Medical Errors •Most medical errors occur when a patient is dispensed the wrong type or dose of medication •Occasionally, they involve surgery and are known as “wrong site” or “wrong body” procedures when the surgeon operates on the wrong part of the body or even the wrong patient •Precise communication with appropriate use of anatomical terminology is critical to prevent medical errors Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Regional Terms (1 of 7) Regional Terms—The body can be divided into two broad regions: Axial (head, neck, and trunk); and Appendicular (upper and lower limbs or appendages) •Each broad region can be divided into several smaller Regions •Regions may be named as nouns, such as the upper arm or brachium, or as adjective with the addition of a suffix such as -al, which is paired with the word “region” to give us the term brachial region Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Regional Terms (2 of 7) Figure 1.8 Regions of the body. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Regional Terms (3 of 7) Figure 1.8 Regions of the body. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Regional Terms (4 of 7) Table 1.1 Regional Terms Region of the Trunk Pertaining To: Abdominal The abdomen Cervical The neck Gluteal The buttocks Inguinal The groin Lumbar The lower back Pelvic The pelvis Pubic The pubis Sacral The sacrum Sternal The sternum Thoracic The chest Vertebral The spinal column Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Regional Terms (5 of 7) Table 1.1 Regional Terms Region of the Head and Face Pertaining To: Buccal The cheek Cranial The skull Cephalic The head Frontal The forehead Mental The chin Nasal The nose Occipital The back of the head Ocular The eye Oral The mouth Otic The ear Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Regional Terms (6 of 7) Table 1.1 Regional Terms Region of the Upper Limb Pertaining To: Acromial The point of the shoulder Antebrachial The forearm Antecubital The anterior surface of the elbow Axillary The armpit Brachial The arm Carpal The wrist Digital The fingers (or toes) Manual The hand Metacarpal The metacarpals (bones of the hand) Palmar The palm Pollex The thumb Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Regional Terms (7 of 7) Table 1.1 Regional Terms Region of the Lower Limb Pertaining To: Coxal The hip Crural The anterior surface of the leg Femoral The thigh Hallux The great toe Metatarsal The metatarsals (bones of the foot) Patellar The anterior surface of the knee Pedal The foot Plantar The sole of the foot Popliteal The posterior surface of the knee Sural The posterior surface of the leg Tarsal The ankle Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Concept Boost: Putting Anatomical Terms Together (1 of 2) 1.Name the Region—Cervical region 2.Add Descriptive Directional Terms— On anterior side, Lateral to midline; Begins inferior to mental region; Ends superior to thoracic region 3.Describe Depth of Incision—Deep to skin and muscle; Superficial to underlying larynx 4.Put It All Together—Incision on anterior cervical region lateral to midline; Extended vertically 1 centimeter inferior to mental region to 2 centimeters superior to thoracic region; Deep to skin and muscle, but superficial to larynx Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Concept Boost: Putting Anatomical Terms Together (2 of 2) 1.Name the Region—Left Crural 2.Add Descriptive Directional Terms— On anterior and medial side; Proximal to tarsal region and distal to patellar region 3.Describe Depth of Incision—Deep to skin and muscle but superficial to bone 4.Put It All Together—Wound on left anteromedial crural region, 10 centimeters proximal to tarsal region and 6 centimeters distal to patellar region; Pellet is lodged deep to skin and muscle but superficial to bone Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Concept Boost Mini Lecture: Putting Anatomical Terms Together Use the link below to view A D A compliant video: Concept Boost Mini Lecture: Putting Anatomical Terms Together https://mediaplayer.pearsoncmg.com/assets/_video.true/bc_amerman_hap_3_concept-boost_ch1 Loading… Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Planes of Section (1 of 4) Planes of Section—Divide a body or body part for examination •Sagittal Plane—Divides body into right and left sections –Midsagittal Plane: Also called a Median Plane; Sections are equal –Parasagittal Plane: Sections are unequal Figure 1.9a Sagittal plane. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Planes of Section (2 of 4) Planes of Section (continued) •Frontal Plane—Also called a Coronal Plane; Divides body into anterior and posterior sections Figure 1.9b Frontal plane. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Planes of Section (3 of 4) Planes of Section (continued) •Transverse Plane— Also called a Horizontal Plane or Cross Section; Divides body into superior and inferior sections or proximal and distal sections •Oblique Plane—Used less frequently; Taken at an angle Figure 1.9c Transverse planes. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.3 Planes of Section (4 of 4) Study Boost: How to Learn Anatomical Terms •Flashcards are popular because research shows that they work –Make customized flashcards with Practice Anatomy Lab™ Flashcards in the Study Area of Mastering® A&P –Make handwritten flashcards •Don’t forget to “Bring It Back” by quizzing yourself and “Mix It Up” by randomizing the order Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Posterior Body Cavity Cavity—Any space within the body; Protects internal organs and allows them to move Posterior Body Cavity— Located on posterior side of body •Cranial Cavity—Within the skull; Includes the brain •Spinal Cavity—Within the vertebral column; Includes the spinal cord •Both cavities are filled with Cerebrospinal Fluid, which bathes both organs Figure 1.10a Posterior body cavity, lateral view. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (1 of 8) Anterior Body Cavity—Has two main divisions separated by the muscular diaphragm •Thoracic Cavity is superior to the diaphragm •Abdominopelvic Cavity is inferior to the diaphragm •Smaller cavities exist within the thoracic and abdominopelvic cavities formed by sheets of tissue termed Serous Membranes Figure 1.10b Anterior body cavity, anterior view. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (2 of 8) Anterior Body Cavity (continued) •Thoracic Cavity –Pleural Cavities—Surround left and right lungs –Mediastinum—Between pleural cavities; Houses heart, great vessels, trachea (windpipe), and esophagus; Not within serous membrane –Pericardial Cavity—Within mediastinum; Within serous membrane that surrounds heart Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (3 of 8) Anterior Body Cavity (continued) •Abdominopelvic Cavity—Subdivided into superior Abdominal Cavity (diaphragm to bony pelvis) and inferior Pelvic Cavity (within bony pelvis) •Contains organs from digestive, lymphatic, urinary, and reproductive systems •Peritoneal Cavity—Abdominal subcavity found within serous membranes Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (4 of 8) Abdominopelvic Cavity can be divided into segments by drawing imaginary lines through its surface •One system divides the cavity into four Quadrants –Right and left upper quadrants (R U Q and L U Q); Right and left lower quadrants (R L Q and L L Q) •A second system divides the cavity into nine Regions –Right and left hypochondriac regions, Right and left lumbar regions; Right and left iliac regions; Epigastric region; Umbilical region; Hypogastric region Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (5 of 8) Figure 1.11 The four quadrants and nine regions of the abdominopelvic cavity. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 Abdominal Pain •Abdominal pain is a common reason for people to seek health care, but the number of structures in the abdominopelvic cavity make diagnoses difficult •The four-quadrant system helps to narrow down potential diagnoses •For example, R L Q pain may be from the appendix, ovaries in female, the first part of the large intestine, or the last portion of the small intestine Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (6 of 8) Serous Membranes—Thin sheets of tissue that fold over to form continuous double-layered structures filled with Serous Fluid to lubricate organs in the cavity –Visceral Layer—Contacts the organ –Parietal Layer—Attaches to surrounding structures Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (7 of 8) Serous Membranes (continued) •Pleural Membranes—Surround the lungs; Includes parietal and visceral pleura •Pericardial Membranes—Surround the heart; Includes parietal and visceral pericardium •Peritoneal Membranes—Surround some abdominal organs (Intraperitoneal); Includes parietal and visceral peritoneum •Organs behind the parietal peritoneum are Retroperitoneal Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 The Anterior Body Cavity (8 of 8) Figure 1.13 The serous membranes of the anterior body cavities. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 Medical Imaging (1 of 2) •Used to look inside patients without surgery; Different forms of radiation form images of internal structures often along specific planes •X-Ray uses ionizing radiation; Chest image is shown (top) •Computed Tomography Scan (C T) uses ionizing radiation; 3-D image is computer generated from data; Transverse section of abdominopelvic and peritoneal cavities is shown (bottom) Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.4 Medical Imaging (2 of 2) •Magnetic Resonance Imaging (M R I) involves the body being placed within a magnetic field; 3-D image is computer generated from data; Transverse section of the abdominopelvic cavity is shown Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Core Principles in Anatomy and Physiology Core Principles—Set of basic concepts of anatomy and physiology that are revisited repeatedly in the text; They are related to maintaining the body’s internal environment •Feedback Loops •Relationship of Structure and Function •Gradients •Cell-Cell Communication Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Overall Theme: Physiological Processes Operate to Maintain the Body’s Homeostasis •Homeostasis—The condition in which the body develops and maintains a relatively stable internal environment –Homeostatic Imbalances—Disturbances in homeostasis can lead to disease or death if uncorrected –Regulated Variables—Variables in the internal environment, such as temperature, blood sugar, and many others, are controlled to stay close to a particular normal value –Controlled Variables—Variables that are manipulated to maintain the regulated variables, such as the process that increases blood sugar from stored carbohydrates Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (1 of 8) Feedback Loops—A change in a regulated variable causes effects that feed back and in turn affect that same variable •Made up of a series of events that lead to an output •As the loops continue, this output then influences the events of the loops themselves •Negative Feedback Loops—Oppose the initial change and reduce the output •Positive Feedback Loops—Reinforce the initial change and increase the output Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (2 of 8) Negative Feedback Loops—Promote stability; Negating any stimulus that moves a variable away from homeostasis •Each variable has a Set Point that includes a Normal Range around that set point •The range differs for individual variables Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (3 of 8) Steps of a Negative Feedback Loop 1.Stimulus—Information that a regulated variable is outside the normal range 2.Receptor or Sensor—Cellular structure that registers the stimulus 3.Control Center—Stimulus is sent to the control center (brain or gland) by the nervous or endocrine systems 4.Effector—The cells or organ that will react 5.Responses—Effector causes the response that will return the variable to the normal range Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (4 of 8) Figure 1.14 Control of room temperature by a negative feedback loop. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (5 of 8) Figure 1.15 Control of body temperature by a negative feedback loop. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (6 of 8) Study Boost: Keeping Track of the Body’s Feedback Loops •Feedback loops occur in all body systems so there are many to remember •As you learn new feedback loops, add them to the Feedback Loops Master List page at the front of the Active-Learning Workbook •Use the list to quiz yourself “Bring It Back,” review feedback loops from other chapters “Space It Out,” and have a friend quiz you from the list in a random order “Mix It Up” Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (7 of 8) Positive Feedback Loops—Less common than negative feedback loops; Increases the response to a stimulus; Reinforces the initial stimulus •Will eventually shut off in response to an external stimulus or some outside event that is not part of the positive feedback loop •Positive feedback loops are often found within a negative feedback loop to produce a quicker response Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Feedback Loops Are a Key Mechanism Used to Maintain Homeostasis (8 of 8) Figure 1.16 Control of blood clotting by a positive feedback loop. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Common Misconceptions about Homeostasis (1 of 2) •Misconception 1: Negative feedback is bad for the body; Positive feedback is good –Under normal circumstances, both types of feedback loops promote homeostasis •Misconception 2: Maintaining homeostasis means the body’s internal environment is static or unchanging –Maintenance of normal ranges does not mean the internal environment is unchanging; Changes are normal and are occurring constantly Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Common Misconceptions about Homeostasis (2 of 2) •Misconception 3: Regulatory mechanisms and feedback loops are either “on” or “off,” like a switch –The internal environment is dynamic so feedback loops always exhibit some degree of activity •Misconception 4: Any physiological variable can be controlled –Variables can only be controlled through feedback loops if receptors exist to detect changes in the set point Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 BioFlix: Homeostasis Use the link below to view A D A compliant video: BioFlix: Homeostasis https://mediaplayer.pearsoncmg.com/assets/loMS4qosEmL53haP3z1Z_eWMupIkyIFv Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Childbirth, Pitocin, and Positive Feedback Loops •Childbirth begins when a woman goes into labor, which occurs by a positive feedback loop •Baby’s head stretches the cervix (stimulus); Data from nerves in the cervix (receptors) are sent to the brain (control center); Uterus (effector) produces hormone oxytocin which stimulates uterine contractions (response); This continues and is amplified until the baby is born, which stops the feedback loop •Pitocin is a synthetic version of oxytocin that is used when labor needs to be artificially started, or induced Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Structure and Function are Related at All Levels of Organization Principle of Complementarity of Structure and Function •The form of a structure is such that it best suits its function; Applies to all levels of organization Figure 1.17 The relationship between structure and function. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Gradients Drive Many Physiological Processes Gradients are present any time more of something exists in one area than another and the two areas are connected •Gradients drive many of our physiological processes Figure 1.18 Examples of gradients. Copyright © 2025, 2019, 2016 Pearson Education, Inc. All Rights Reserved 1.5 Cell-Cell Communication is Required to Coordinate Body Functions •Cells communicate with each other to maintain homeostasis •Electrical Signals are transmitted between neighboring cells •Chemical Messengers released from cells may work on neighboring cells or move to other cells through body fluids Figure 1.19 Communication between a nerve cell and a muscle cell.

Collocations topic: Texture