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Microbe
A microscopic organism, including bacteria, archaea, eukarya, and viruses.
Estimated Microbial Diversity
Up to 99.99% of bacterial species may remain undiscovered, with only 30,000–40,000 identified.
Bacterial Diversity in Humans
Humans harbor about 500–1000 species of bacteria on their bodies, with the highest diversity found in the gut and skin.
High Surface Area-to-Volume Ratio
Allows small microbes to carry out essential life functions efficiently through diffusion.
Domains of Life
The three domains are Bacteria, Archaea, and Eukarya.
Cocci
Spherical shape of bacteria.
Bacilli
Rod-shaped bacteria.
Spirilla
Spiral-shaped bacteria.
Capsule
The outermost protective layer of a bacterial cell.
Cell Wall
Provides structural support and protection outside the plasma membrane.
Plasma Membrane
Regulates what enters and leaves the cytoplasm of a cell.
Plasmid
A small circular piece of DNA in bacteria, often carrying antibiotic resistance genes.
Pilus
Hair-like appendages involved in attachment and DNA transfer between bacteria.
Gram-Positive Bacteria
Bacteria with a thick glycoprotein layer exposed on the outside of the cell wall.
Gram-Negative Bacteria
Bacteria with a glycoprotein layer shielded by an additional outer membrane.
Conjugation
The transfer of DNA between bacteria via a physical connection.
Transduction
The process by which a virus transfers bacterial DNA from one bacterium to another.
Transformation
The uptake of DNA from the environment by a bacterium.
Impact of Bacteria on Digestion
Some bacteria, specifically intestinal archaea, assist in digesting tough food chemicals.
Human Microbiome
The community of microbes residing in and on the human body.
Microbial Cells vs. Human Cells
The human body contains about 68 trillion microbial cells, slightly more than human cells.
Independent Variable (IV)
The factor manipulated in an experiment, like the source of microbiome transplant.
Dependent Variable (DV)
The factor measured to see if it changes in response to the independent variable.
Stacked Bar Graphs
Used to show total quantities and their components, like cell types in the human body.
Side-by-Side Bar Graphs
Used to compare different independent categories or experimental results.
Pie Charts
Represent proportions of categories within a whole.
Behavioral Influence of Gut Microbes
Gut bacteria can affect behavior, appetite, and mood through neural signals.
Symbiotic Relationships
Mutually beneficial relationships between bacteria and humans.
Gas Production by Gut Microbes
Gut microbial activity during digestion can lead to gas production.
Causal Link
A direct relationship established between a change in microbial community and a behavior change.
Necessary Role of Microbial Transplants
Transplants help establish causation, rather than correlation, between microbiomes and behavior.
Mutation Rate in Bacteria
Bacteria generally exhibit a high mutation rate influenced by their smaller genome size.
Horizontal Gene Transfer
The process by which bacteria share genetic material with other bacteria.