it becomes damaged by chronic secretion of cortisol
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social status in animals
- subordinate animals have chronically high levels of stress, which compromises ability to respond to stress over time, and leads to compromised immune system - benefit of high social status: predictability and controllability of environment
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diagram of contributions to stress response
as sense of control or ability to cope increases, our feelings range along continuum from depression, anxiety, stress, to excitement
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psychoneuroimmunology
psychological influences on neurological component of immune response
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what happened when rats where given sugar water
- rats given sugar water with a drug that suppresses immune system - later, sugar water along suppressed immune system
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immune system function
identify and eliminate foreign materials (antigens)
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2 parts of immune system
- humoral - cellular includes white blood cells (leukocytes), B and T cells (lymphocytes), and macrophages
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macrophages
- body's first line of defense - surround antigens and destroy them - signal lymphocytes
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lymphocyte B cells
- in humoral - release molecules that seek antigens in blood with purpose of neutralizing them - produce immunoglobulins that act as antibodies, which combine with antigens to neutralize them
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memory B cells
created so next time antigen is encountered, immune response is faster
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lymphocyte T cells
- cellular part - don't produce antibodies - killer T cells destroy viruses and cancer cells - memory T cells created to speed up response to same antigen - T4 cells (helper T cells) enhance immune response by signaling B cells to produce antibodies and tell other T cells to destroy antigen - suppressor T cells suppress production of antibodies by B cells when not needed
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what happens with too many T4 cells
helper T cells overreact and attack normal cells
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in developing world, most die within _______ of AIDS
1 year
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what is best treatment for AIDS
- highly active antiretroviral therapy (HAART) - suppresses virus, slows progression and decreased mortality - severe side effects
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US AIDS cases by mode of transmission - male to male sexual contact: _____% - heterosexual contact: ______ % - injection drug use: _________% - other: _______%
50%; 32%; 17%; 1%
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what exacerbates AIDS progression
- high stress - low social suppor
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outcomes of cognitive-behavioral stress-management (CBSM) in those with AIDS
psychological factors that have been used to explain individual differences in blood pressure
- personality - coping style - level of stress
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psychological factors that contribute to cardiovascular disease
- loneliness - depression - feelings of uncontrollability
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coronary heart disease
blockage of arteries supplying blood to heart
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psychological and behavioral risk factors associated with coronary heart disease
- stress, anxiety, anger - poor coping skills - low social support
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what is CHD linked to
- type A behavior pattern (anger, excessive drive and competitiveness, impatience, accelerated speech, agitated motor activity) - chronic negative affect, low socioeconomic status, and stressful experiences
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what factors reduce risk of CHD
positive emotions and optimistic style
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reverse capacity model for risk factors for CHD
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acute pain
follows an injury and disappears once injury heals/effectively treated
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chronic pain
may begin with acute episode but doesn't decrease over time
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pain behaviors
limping, complaining, avoiding activities
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why is severity of pain not a good predictor of one's reaction to it
some experience intense pain and continue to work productively, rarely seek medical service, and lead normal lives
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chronic pain is worsened by
- low perceived control - negative emotion - poor coping skills - low social support
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pain behaviors may be increased by
- compensation (e.g., paid time off) - social reinforcement (sympathy)
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gate control theory of pain
neurological processes (anxiety, fear, intense concentration) affect the degree to which pain is detected - negative emotions - message from brain is to be vigilant against danger - positive emotions - brain sends inhibitory signal to close gate
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endogenous (natural) opioids
- pain-inhibiting natural chemicals that may be increased by exercise - called endorphins
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why do females have additional pain-regulation mechanisms
- to facilitate childbirth - neurochemistry may be based on estrogen-dependent neuronal system
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nature of chronic fatigue
- lack of energy and fatigue that doesn't improve with adequate sleep - may have aches and pains or low fever
Core beliefs of someone with chronic fatigue syndrome
I am inadequate
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lifestyle of someone with chronic fatigue syndrome
- achievement-oriented and hard working - puts on brave face - doesn't ask for help
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thoughts of someone with chronic fatigue syndrome
- I must be physically ill - i'm making myself worse - there's nothing I can do - I should try harder to cope - I can beat this
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biofeedback
- psychosocial treatment of physical disorder - monitor and control bodily responses (heart rate, blood pressure, muscle tension, EEG rhythms) - increase sense of control - improves patient's ability to control bodily processes
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relaxation and meditation
- psychosocial treatment of physical disorder - progressive muscle relaxation - transcendental meditation: focuses attention on repeated mantra - increased sense of control and mastery - may improve headache, hypertension, acute and chronic pain
- medication decreases efficacy of comprehensive programs - high relapse when stopped - tolerance built over time
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coping through denial
- denial about physical condition can be helpful - helpful at early stages - later, more helpful to face situation
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what is the leading cause of death from ages 1-45
accidents
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injury prevention
- repeated warnings not enough - programmatic efforts needed (teach children to escape fires and cross streets)
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AIDS prevention
- preventable by changing behaviors (safe-sex, sanitary use of needles, regular check-ups, strong peer support programs)
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smoking cessation in China
- capitalize on family relationships (children persuade fathers to stop) - distribute anti-smoking literature - target at-risk populations
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stanford three community study
- looking to reduce risk factors of CHD - conducted in 3 similar communities - each community either got: no intervention, media blitz, media blitz plus face-to-face intervention - highest benefit from media blitz plus live intervention
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what is abnormal sexual behavior?
- normative facts and statistics - cultural considerations - gender differences in sexual behavior and attitudes
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how many partners in a lifetime and past year
- 15 or more (lifetime): men = 21.4%, female = 8.3% - 4 or more (past year): men = 6%; female = 2.9%
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homosexual sex attraction or behavior statistics
men = 10% women = 9%
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sex in age 75-85 statistics
men = 38.5% active female = 16.7% active
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gender differences in masturbation
men = 72% report ever masturbating female = 42% report ever masturbating - males masturbation may be easier and physical gratification more emphasized for men
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gender differences in casual premarital sex
men are more permissive, but the gap is shrinking
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gender differences in elements of satisfaction
- women are more likely to seek demonstrations of love and intimacy - men are more likely to focus on arousal
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no differences in gender differences of
- acceptability of homosexuality - acceptability of masturbation - importance of sexual satisfaction
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sexual self-schemas
beliefs about one's own sexuality
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gender differences in sexual beliefs
- females more likely to value experience of passionate and romantic feelings - minority of females hold embarrassed, conservative, or self-conscious views toward sex - males have fewer negative core beliefs about sex - men are more likely to emphasize dominance and aggression
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cultural differences on views on sexuality in children
- Sambia believe receiving semen contributes to development in children (emphasize homosexual oral sex between young boys) - Munda emphasize mild heterosexual activity (mutual masturbation) among cohabitating children
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development of sexual orientation
- bio-psycho-social influences - homosexuality (only small genetic component: 50% of identical twins raised together do NOT share same sexual orientation)
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why did DSM III remove homosexuality as a disorder
- no physiological differences in arousal between gay and straight - no difference in rate of psychological disturbance - gender identity confusion no more common in homosexuals - lack of full societal acceptance and different behaviors, homosexual sexual concerns differ from heterosexuals' concerns
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sexual dysfunctions
- involve desire, arousal, and/or orgasm - pain associated with sex can lead to additional dysfunction
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sexual dysfunction present for how long to make a diagnosis
6+ months
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desire phase
sexual urges occur in response to sexual cues or fantasies
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arousal stage
sense of sexual pleasure and physiological signs of sexual arousal
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plateau phase
brief period occurs before orgasm
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orgasm phase
- in males, feelings of inevitability of ejaculation, followed by ejaculation - females, contractions of walls of lower third of vagina
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resolution phase
decrease in arousal after orgasm (particularly in men)
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prevalence of sexual dysfunctions
- common and not always distressing - 40% of men have difficulty with erection/ejaculation, 63% of women have problems with arousal/orgasm
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classification of sexual dysfunctions
- lifelong vs. acquired - generalized vs. situational - psychological factors alone - psychological factors combined with medical condition
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lifelong
chronic condition present during person's entire sexual life
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acquired
disorder begins after sex has been normal
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generalized
occurs every time individual attempts sex
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situational
occurs with some partners or at certain times
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desire disorders in men/women
- men: hypoactive sexual desire - women: female sexual interest/arousal disorder
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arousal disorders in men/women
- men: erectile disorder - women: female sexual interest/arousal disorder
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orgasm disorder in men/women
- men: erectile disorder - women: female sexual interest/arousal disorder
- accounts for half of all complaints at sexuality clinics - affects 5% of men
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DSM-5 for male hypoactive sexual desire disorder
1. persistently or recurrently deficient (or absent) sexual/erotic thoughts or fantasies and desire for sexual activity 2. symptoms have persisted for minimum of 6 months 3. symptoms cause distress in individual 4. sexual dysfunction not better explained by nonsexual disorder or consequence of relationship distress or other stressors and isn't attributable to medication or other medical condition specify whether: lifelong or acquired type specify whether: generalized or situational type
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erectile disorder
- difficulty achieving or maintaining erection - sexual desire intact
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statistics for erectile disorder
- most common problem for which men seek treatment - prevalence increases with age (60% of men over 60 experience erectile dysfunction)
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female sexual interest/arousal disorder prevalence