Bone Formation and Development

endochondral ossification

process in which bone forms by replacing hyaline cartilage

intramembranous ossification

process by which bone forms directly from mesenchymal tissue

modeling

process, during bone growth, by which bone is resorbed on one surface of a bone and deposited on another

ossification

process of bone formation; also called osteogenesis

ossification center

cluster of osteoblasts found in the early stages of intramembranous ossification

osteoid

uncalcified bone matrix secreted by osteoblasts

perichondrium

membrane that covers cartilage

primary ossification center

region, deep in the periosteal collar of the diaphysis, where bone development starts during endochondral ossification

remodeling

process by which osteoclasts resorb old or damaged bone at the same time as and on the same surface where osteoblasts form new bone to replace that which is resorbed

secondary ossification center

region of bone development in the epiphyses