composed of bones, cartilages, and ligaments joined tightly to form a strong, flexible framework for the body
Skeletal system
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joint surfaces in the mature skeleton
Cartilage location
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A cord or band of tough collagenous tissue binding one organ to another, especially one bone to another
ligaments
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soft bloody or fatty material enclosed in the bones
bone marrow
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support protection movement blood formation storage
functions of skeletal system
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limbs and vertebral column support the body mandible and maxilla support the teeth
Support function
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bones enclose and protect the brain, spinal cord, lungs, heart, and pelvic viscera
Protection Function
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movements of the limbs, and other movements such as breathing, are produced by the action of muscles on bones
Movement Function
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Red Bone marrow is the major producer of blood cells
Blood Formation Function
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skeleton stores calcium and phosphorus fatty bone marrow has fuel
Storage Function
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affects blood sugar regulation, fertility, and brain function in mammals
other functions of the skeleton
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osseous tissue, a connective tissue with a hard, calcified matrix
bone
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compact (dense) bone spongy bone
2 forms of bone
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consists of a solid matrix
compact (dense) bone
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porous lattice honeycombed with spaces
spongy bone
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interior of bone
where is spongy bone found
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osseous tissue organ (femur)
2 meanings for bone
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osteogenic osteoblasts osteocytes osteoclasts
Four kinds of bone cells
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bone surface, beneath the fibrous connective tissue membrane that covers a bone
osteogenic cells location
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give rise to osteoblasts only bone cells that divide and make more bone cells
osteogenic cells function
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lie in a single layer on the bone surface, somewhat resembling a cuboidal epithelium
osteoblasts location
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bone-forming cells that synthesize the organic matter of the bone and promote its mineralization
osteoblasts function
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reside in cavities called lacunae, which are connected to each other by channels called canaliculi
Osteocyte locations
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pass nutrients and chemical signals pass metabolic wastes orchestrate bone remodeling maintenance of bone density sense mechanical stress secrete signals that adjust bone shape and density
Osteocyte function
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90%
how much of bone cells are osteocytes
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osteoblasts become trapped in the matrix the deposit
how are osteocytes made
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lie one the bone surface lie in pits that they have eroded
osteoclasts location
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bone-dissolving cells that develop from a separate line of bone marrow stem cells
osteoclasts function
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stony matter that surrounds the osteocytes and lacunae
matrix of osseous tissue
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bones being soft and bending easily
deficient in minerals can cause
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childhood mineral deficiency
rickets
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adulthood mineral deficiency
osteomalacia
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flexibility
collagen gives bones
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consists of porous lattice of slender rods and plates called trabeculae
spongy (cancellous) bone
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bone marrow and small blood vessels
spaces of spongy tissue are filled with
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forms the hard outer shell of the bone. Prevents bone marrow from seeping out and provides a solid attachment surfaces for muscles, tendons, and ligaments
compact (dense) bone
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A structural unit of compact bone consisting of a central canal surrounded by concentric cylindrical layers of matrix
osteons
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A little plate or layer in compact bone that arranges around a central canal
lamellae
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long bones
what are the most important bone for movement
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The shaft of a long bone (elongated midsection)
diaphysis
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The head of a long bone (expanded end)
epiphysis
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provides leverage
shaft function
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strengthen a joint and provide added surface area to for the attachment of tendons and ligaments
head function
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A thin layer of hyaline cartilage covering the articular surface of a bone at a synovial joint
articular cartilage
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serving to reduce friction and ease joint movement
articular cartilage function
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spongy bone
what is the head and shaft filled with
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marrow (medullary) cavity of the shaft and spaces between the spongy bone
where is bone marrow occupying
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the line marking the site of an epiphyseal plate that has has stopped growing and become ossified.
epiphyseal line
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shieldlike plates that protect delicate organs
flat bones
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sternum- heart cranial bones- brain
organs flat bones protect
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bones that don't fit the description of flat and long bones
short and irregular bones
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A layer of fibrous connective tissue covering the surface of a bone.
periosteum
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provides strong attachment and continuity from muscle to tendon to bone
periosteum function
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a thin layer of reticular connective tissue separating the bone from the bone marrow (internal surface)
endosteum
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red bone marrow yellow bone marrow
2 types of bone marrow
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serves to produce blood cells and platelets, fills nearly every bone of a child's skeleton, but is more distribution in adults
red bone marrow
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fatty bone marrow that dominates the long limb bones of adults
yellow bone marrow
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formation of bone
ossification
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intramembranous endochondral
2 types of ossificaiton
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A process in which a sheet of mesenchyme becomes calcified to form a bone, employed primarily for the production of flat bones such as those of the cranium.
intramembranous ossification
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fontanels
another name for gaps
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A process in which a hyaline cartilage precursor (model) is replaced by calcified tissue to form a bone; employed for the production of most bones of the body except for flat bones of the skull and part of the clavicle.
endochondral ossification
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hyaline cartilage covered with pericondrium
Step 1 of Endochondral Ossification
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in a primary ossification center chondrocytes enlarge and die. Thin walls calcify. Osteoblasts deposit thin layer of bone around model, forming a collar
Step 2 of Endochondral Ossification
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blood vessels pierce the periosteum at the primary ossification center. Osteoclasts digest calcified tissues, hollowing out the shaft and creating the primary marrow cavity. Osteoblasts deposit layers of bone, thickening shaft. Secondary ossification center develops
Step 3 of Endochondral Ossification
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secondary ossification center has hollowed out secondary marrow cavity. Another ossification center appears
Step 4 of Endochondral Ossification
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epiphyseal plates separates marrow cavities. Plate is a growth zone
Step 5 of Endochondral Ossification
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cartilage in epiphyseal plate is depleted marrow cavities unite into single medullary cavity bones can no longer grow
Final step of endochondral ossification
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accommodate changing forces applies to the skeleton addition of new tissue to the bone surface
why do bone change size and shape
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stimulates an increase in bone mass
what does tension do to the skeleton
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maintenance growth remodeling exchange minerals with extracellular fluid
bones functions as an metabolically active organ
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calcium and phosphate
skeleton is the body's primary reservoir for
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bone structure component of DNA, RNA, ATP, phospholipids, and other compounds
phosphate function
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bone structure muscle contraction, blood clotting, exocytosis, nervous communication, and cellular responses to hormones
calcium function
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crystallization process in which osteoblasts extract calcium, phosphate, and other ions from the blood and deposit them in the osseous tissue
mineral deposition
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process in which the osteoclasts dissolve bone, releasing minerals into the blood and making them available for other uses
resorption
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A deficiency of calcium ions in the blood that causes dysfunctions ranging from muscle tremor to tetanus (inability of the muscle to relax)
hypocalcemia
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An excess of calcium ions in the blood that depresses nervous, muscular, and cardiac function
Hypercalcemia
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calcitriol parathyroid hormone
what 2 hormones regulates calcium homeostasis
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most active form of vitamin D promotes calcium absorption in the small intestine reduces urinary loss of calcium stimulates osteoclasts to release calcium from the bones
calcitriol
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rickets
low levels of calcitriol result in
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secreted by the parathyroid glands stimulates bone resorption by osteoclasts promotes calcium reabsorption by kidneys promotes calcitriol synthesis
parathyroid hormone (PTH)
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fracture results from an unusual stress on a bone
stress fracture
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bone has been weakened by some other condition, and it fractures under a stress that a healthy bone would withstand
pathological fracture
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any fracture that breaks through the skin
open fracture
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fracture does not break through skin
closed fracture
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descriptions of bones that include a variety of ridges, spines, bumps, depressions, holes, and joint surfaces
bone markings
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a tubular passage or tunnel in a bone
Canal Bone marking
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a rounded knob
condyle Bone marking
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a narrow ridge
crest Bone marking
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a flare superior to a condyle
epicondyle Bone marking
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a smooth joint surface that is flat or only slightly concave or convex