Ether Reactions

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6 Terms

1
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1º Alcohols (2 eq.) + H2SO4 (cat.), heat

symmetric, linear ether is produced with water

2
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1º Alcohol + NaH, R—Br

Asymmetric, linear ether is produced

3
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1º Alcohols + Bulky alkene

asymmetric bulky ethers is produced

4
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Acid-Catalyzed Ether Cleavage

Ether + HX, heat

Separates ether and adds halogen where the oxygen was (two products)

5
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Alcohol + TIPS—Cl, Et3N

Replaces -OH with -OTIPS

6
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R—OTIPS + TBAF, H3O+

Replaces -OTIPS with -OH and also produces F-TIPS