Classcal Pathway Proteins, Alternative Pathway Proteins, Mannose-Binding-Lectin Pathway Proteins

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16 Terms

1
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Binds to Fc region of IgM and IgG

C1q

2
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Activated C1s

C1r

3
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part of C3 convertase

C4

4
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binds to C4b — forms C3 convertase

C2

5
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key to all intermediate pathway

C3

6
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initiates membrane attack complex

C5

7
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binds to C5b in MAC

C6

8
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binds to C5b6 in MAC

C7

9
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starts pore formation non membrane

C8

10
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polymerize lysis

C9

11
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binds to C3b to form C3 convertase

Factor B

12
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cleaves factor B

Factor D

13
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stabilize C3bBb — which is the unstable C3 convertase

Properdin

14
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binds to mannose

Mannose Binding Lectin

15
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unknown

Mannose Binding Lectin Associated Serine Protease 1

16
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cleaves C2 and C4

Mannose Binding Lectin Associated Serine Protease 2