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Vocabulary flashcards covering key structures, cells, hormones, processes, and functions of the male reproductive system as described in the lecture notes.
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Gonads
Primary sex organs; in males this refers to the testes, which produce sperm and androgens.
Testes
Male gonads where spermatogenesis occurs and testosterone is produced.
Epididymis
Coiled duct on the posterior surface of the testis where sperm mature and are stored; has head, body, and tail.
Efferent ductules
Passages that transport sperm from the testis to the epididymis, aided by cilia.
Ductus deferens (vas deferens)
Muscular duct that carries sperm from the epididymis to the urethra; includes the ampulla.
Ampulla of the ductus deferens
Expanded region of the ductus deferens just before the seminal vesicle junction, where sperm begin to mix with seminal fluids.
Seminal glands (seminal vesicles)
Glands that produce most of the semen volume; fluids contain fructose, citrate, and prostaglandins.
Prostate gland
Gland that produces prostatic fluid, contributing to about a quarter of semen volume.
Bulbourethral glands (Cowper’s glands)
Glands that secrete thick, alkaline mucus to neutralize acids and lubricate the penis tip.
Semen
Fluid containing sperm and secretions from the seminal glands, prostate, nurse cells, and epididymis.
Seminiferous tubules
Tightly coiled tubes in the testes where spermatogenesis occurs; contain germ and supporting cells.
Sertoli cells (nurse cells)
Support germ cell development, form the blood-testis barrier, and secrete inhibin and ABP.
Blood-testis barrier
Tight junctions between Sertoli cells that protect developing germ cells from immune attack.
Interstitial (Leydig) cells
Cells located between seminiferous tubules that produce testosterone.
Testosterone
Male sex hormone; stimulates spermatogenesis and secondary sex characteristics; provides negative feedback to GnRH and gonadotropins.
Gonadotropin-releasing hormone (GnRH)
Hormone released by the hypothalamus that stimulates the anterior pituitary to secrete FSH and LH.
FSH (follicle-stimulating hormone)
Pituitary hormone that stimulates Sertoli cells to support spermatogenesis and ABP production.
LH (luteinizing hormone)
Pituitary hormone that stimulates Leydig cells to secrete testosterone.
Androgen-binding protein (ABP)
Protein from Sertoli cells that binds testosterone to maintain high intratubular testosterone levels.
Inhibin
Hormone from Sertoli cells that inhibits FSH secretion via negative feedback.
Spermatogonia
Diploid germ cells on the basement membrane of seminiferous tubules that divide by mitosis to form more spermatogonia and primary spermatocytes.
Primary spermatocyte
Diploid cell derived from a spermatogonium that undergoes meiosis I.
Secondary spermatocyte
Haploid cell produced after meiosis I that undergoes meiosis II to form spermatids.
Spermatid
Haploid cell produced by meiosis II that matures into a spermatozoon during spermiogenesis.
Sperm (spermatozoon)
Mature male gamete with a head (nucleus and acrosome), midpiece (mitochondria), and tail (flagellum).
Spermiogenesis
Final maturation step in which spermatids become mature spermatozoa, shedding cytoplasm and forming the tail and acrosome.
Meiosis I
First meiotic division; homologous chromosomes separate, forming two haploid secondary spermatocytes with recombined genetic material.
Meiosis II
Second meiotic division; sister chromatids separate to form four haploid spermatids.
Mitosis
Cell division that produces two genetically identical diploid daughter cells; precedes meiosis in spermatogenesis.
Capacitation
Physiological changes sperm undergo in the female reproductive tract that enable fertilization.
Erection
Parasympathetic-mediated relaxation of penile arteries and dilation of erectile tissues, leading to penile rigidity.
Emission
Sympathetic-driven peristaltic movement that moves semen into the prostatic urethra.
Ejaculation
Rhythmic contractions of pelvic floor muscles expel semen through the urethra; sphincters regulate flow.
Corpora cavernosa
Two dorsal erectile tissues that fill with blood during erection.
Corpus spongiosum
A single erectile tissue surrounding the urethra; helps keep the urethral opening open during erection.
Tunica albuginea
Dense connective tissue sheath surrounding the corpora cavernosa and forming a rigid support.
Tunica vaginalis
Serous covering of the testes with parietal and visceral layers.
Scrotum
Sac that houses the testes; composed of skin, dartos muscle, fascia, cremaster muscle, and tunica vaginalis; helps regulate temperature.
Cremaster muscle
Skeletal muscle that elevates the testes to regulate temperature; part of the spermatic cord system.
Dartos muscle
Smooth muscle that wrinkles the scrotal skin to reduce heat loss or gain.
Pampiniform plexus
Venous network surrounding testicular arteries that cools arterial blood to protect sperm viability.
Spermatic cord
Cord containing the ductus deferens, vessels, nerves, and lymphatics that travels through the inguinal canal.
Rete testis
Network of ducts that connect seminiferous tubules to efferent ductules.
Prostatic urethra
Part of the urethra that passes through the prostate; receives secretions from the prostate.
Membranous urethra
Segment of the urethra between the prostate and the penis surrounded by muscle.
Spongy (penile) urethra
Longest segment of the urethra within the penis; carries urine and semen.
Semen volume and composition
Typically 2-5 mL per ejaculation; 20-100 million sperm/mL; semen contains sperm and secretions from seminal vesicles, prostate, nurse cells, and epididymis; secretions provide energy, protection, and motility cues.
Semen fluid components (fructose, citrate, prostaglandins)
Nutrients and signaling molecules in semen that nourish sperm, stimulate motility, and facilitate transport.
Capacitation vs fertilization
Capacitation is the functional activation of sperm in the female tract, enabling fertilization capability.
Prostate cancer and BPH
Common male prostate disorders; BPH is benign enlargement; cancer is a major cancer risk in older men.