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Advantage of sexual reproduction
→ Produces genetic variation, increasing adaptability to changing environments.
Spermatogenisis steps
Oogenesis steps
Advantage of asexual reproduction
→ Rapid production of genetically identical offspring well adapted to stable environments.
Meiosis
A type of cell division that reduces the chromosome number by half, resulting in four genetically diverse gametes. This process is essential for sexual reproduction.
Haploid (n)
→ Having one set of chromosomes.
Diploid (2n)
→ Having two sets of chromosomes.
Gamete
→ A haploid sex cell (sperm or egg) capable of fusion at fertilization.
Zygote
→ A diploid cell formed by fusion of two haploid gametes.
Testis
→ Produces sperm and testosterone.
Epididymis
→ Stores and matures sperm before ejaculation.
Vas deferens
→ Transports sperm from epididymis to urethra.
Seminal vesicle
→ Produces fructose-rich fluid to supply energy for sperm.
Cowper’s gland
→ Secretes alkaline mucus to lubricate and neutralize the urethra.
Prostate gland
→ Produces alkaline fluid that improves sperm survival.
Cervix
→ Muscular opening between uterus and vagina.
Oestradiol
→ Repairs and thickens the endometrium and stimulates LH release.
Progesterone
→ Maintains the endometrium for pregnancy.
FSH (Follicle-stimulating hormone)
→ Stimulates follicle development and spermatogenesis.
LH (Luteinizing hormone)
→ Triggers ovulation and stimulates testosterone production.
Ovulation
→ Release of a secondary oocyte from the ovary.
Corpus luteum
→ Secretes progesterone after ovulation.
Superovulation
→ Hormonal stimulation causing multiple eggs to mature simultaneously.
Acrosome
→ Structure containing enzymes that digest the zona pellucida.
Acrosome reaction
→ Release of enzymes allowing sperm penetration of the egg.
Cortical granules
→ Vesicles that release enzymes after fertilization.
Cortical reaction
→ Hardening of the zona pellucida to prevent polyspermy.
1. MENSTRUAL CYCLE (OVARIAN + UTERINE)
menstruation, repair, ovulation, luteal, shed
→ FOLP (FSH, Oestradiol, LH, Progesterone)
→ Low → rise → surge → high → fall
→ menstruation: all low
→ repair: FSH + oestradiol rise
→ ovulation: LH surge
→ luteal: progesterone high
→ shed: progesterone falls
Pregnancy maintenance
implantation, early pregnancy, late pregnancy
→ HCP (hCG, Corpus luteum, Placenta)
→ Maintain → transfer → maintain
→ early: hCG maintains corpus luteum
→ corpus luteum: progesterone high
→ later: placenta secretes progesterone + oestradiol
Childbirth
uterine stretch, contractions, birth
→ SOPP (Stretch, Oxytocin, Positive feedback, Push)
→ Low P → high O → more O
→ progesterone falls
→ oxytocin released
→ contractions strengthen via positive feedback
→ cervix dilates → birth
Puberty
childhood inhibition, hormone release, maturity
→ GnFLUSH (GnRH → FSH/LH → sex hormones)
→ Low → rise → develop
→ GnRH increases
→ FSH + LH increase
→ sex hormones increase
→ secondary sexual characteristics develop
Oxytocin
→ Hormone that stimulates uterine contractions.
positive feedback loop during child birth contractions increase oxytocin relase
Set Point
Ideal value for a variable (e.g. 37°C body temp)
Insulin
Function: Lowers blood glucose
Source: Beta cells
Action: Glucose → Glycogen
Glucagon
Function: Raises blood glucose
Source: Alpha cells
Action: Glycogen → Glucose
Islets of Langerhans
Definition: Hormone-producing regions of pancreas
Mnemonic: “Islets = hormone islands”
Glycogen
Definition: Storage form of glucose
Location: Liver & muscles
Mnemonic: “GLYCO-GEN = glucose generator”
Hypothalamus
Function: Temperature control center
Thyroxine
Effect: Increases metabolic rate
Kidney
Function: Excretion + osmoregulation
Nephron
Definition: Functional unit of kidney
Kidney structure
glomerulus, carries out ultrafiltration of blood; Bowman’s capsule collects the filtrate; proximal convoluted tubule, reabsorbs glucose, amino acids, ions, and most water by active transport and diffusion; descending limb of the loop of Henle, is permeable to water allowing water to leave by osmosis and concentrate the filtrate; ascending limb of the loop of Henle, is impermeable to water and pumps sodium and chloride ions out to create a salt gradient; distal convoluted tubule, regulates ion balance and pH and responds to aldosterone; collecting duct, reabsorbs water under the control of ADH and determines urine concentration; renal pelvis collects urine; ureter transports urine to the bladder.
Signal Transduction
Definition: Series of reactions triggered after ligand binds
Quorum Sensing
Definition: Bacterial communication using chemical signals to coordinate behavior
Autoinducers
Definition: Signalling molecules released by bacteria