Hypersensitivity and Autoimmune Diseases

Hypersensitivity

The phenomenon of damage caused by the immune system while trying to combat an insult

type I hypersensitivity

what type of hypersensitivity?

anaphylaxis

type I hypersensitivity

what type of hypersensitivity?

asthma

eczema

hay fever

reactions to food

antihistamine

used as medication for type I hypersensitivity

type II hypersensitivity

what type of hypersensitivity?

antibody dependent cytotoxic hypersensitivity

type II

what type of hypersensitivity?

complement fixing

functional fixing

functional fixing

what kind of antibody fixing?

antibodies interfere with cell function

complement fixing

what kind of antibody fixing?

antibodies cause destruction of the target cell and damage the surrounding cells

type II

what type of hypersensitivity?

rhesus incompatibility

type II

what type of hypersensitivity?

antibodies react with antigens fixed to the cells

type III hypersensitivity

what type of hypersensitivity?

immune complex mediated hypersensitivity?

type III

what type of hypersensitivity?

antibody driven process, they react with antigens and give rise to "serum sickness"

type III

what type of hypersensitivity?

farmer's lung alveolitis

type IV

what type of hypersensitivity?

cell mediated hypersensitivity

type IV

what type of hypersensitivity?

T lymphocytes recruit and activate other T cells and macrophages and produce local tissue damage and granuloma formation

type IV

what type of hypersensitivity?

mantoux test

GI diseases

primary biliary cirrhosis

ulcerative colitis

atrophic gastritis

cardiovascular diseases

pernicious anemia

hemolytic anemia

idiopathic thrombocytopenia

leukopenia

endocrine diseases

insulin dependent diabetes, thyrotoxicosis and Hashimoto's thyroiditis

musculoskeletal diseases

mixed connective tissue diseases

rheumatoid arthritis

systemic lupus erythematosus

myasthenia gravis

dermatology diseases

dermatomyositis

scleroderma