biology - topic 2 - non specific response
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7 Terms
chemical barriers - tears and saliva
contain lysozymes (protease) that hydrolyse pathogens
chemical barriers - stomach
hydrochloric acid hydrolyses pathogens
physical barriers
skin, mucus, cilia, blood clotting, scabs
phagocytosis
phagocyte detects chemical trail of pathogen and moves towards it down a concentration gradient
receptors attach to pathogen and engulf it by endocytosis forming a phagosome around it
lysosomes migrate to the phagosome, fuse to it and release lysozymes which hydrolyse the pathogen
hydrolysed products from pathogen are absorbed by phagocyte and antigens presented on the CSM - becoming an antigen presenting cell known as a macrophage
