BTEC 6302 - Test 1 Review

"ATryn, was the first recombinant human protein produced in mammary glands of goats that was approved by the Food and Drug Administration. What was it used for?" \n \n Treat dwarfism \n Prevent diarrhea \n Promote blood clots \n Prevent nausea \n Reduce clotting of blood

Reduce clotting of blood

What is the best definition of biotechnology? \n \n The use of technology to improve man for the benefit of their pets \n The use of technology to improve humans for the benefit of plants \n The use of technology to improve animals \n The use of technology to improve humans \n The use of technology to improve organisms or their products for the benefit of man

The use of technology to improve organisms or their products for the benefit of man

The AquaAdvantage salmon was genetically engineered to be much faster growing than the native salmon counterpart. What is the main concern why FDA took 19 years to approve its commercialization? \n \n It might be capable of transmitting a virus to sushi lovers \n It may lead to the extinction of native salmon species \n The nutritional content has changed significantly compared to the native salmon \n It carries a virus that can kill the native salmon \n An antibiotic resistance gene is present in the recombinant DNA that was used

It may lead to the extinction of native salmon species

The first genetically modified microorganism that was granted a patent was: \n \n For producing a animal hormone which increases body mass and milk production \n For use in cleaning up oil spills \n For protecting plants against fungal pathogens \n For use in cheese production \n For producing a human protein used to control blood sugar levels

For use in cleaning up oil spills

The Genzyme plant in Massachusetts produces biotherapeutic enzyme replacement for people with Gaucher's disease. The plant was shut down by the FDA at one point causing a drug shortage concern for many patients. What was the reason for the shut down?

Vials of the therapeutic protein were found contaminated with a simian virus
Glass pieces were found inside the vials of drugs
The cell cultures that churn out the therapeutic protein got contaminated with a virus
FDA found unsanitary manufacturing conditions
FDA found evidence of poor documentation or record keeping

The cell cultures that churn out the therapeutic protein got contaminated with a virus

What is not a risk encountered in pre-natal diagnostic testing by amniocentesis? \n \n Miscarriage of the fetus \n Profuse bleeding in woman \n Fetal injury \n Bloating in pregnant women \n Faulty diagnosis leading to unnecessary abortion

Bloating in pregnant women

"Which of these drugs, that can be produced using microbes, is used to stimulate production of red blood cells in patients with anemia, but is also a banned performance enhancing drug for athletes?"

Growth hormone
Erythropoietin
Interferon
Insulin
Colony stimulating factor

Erythropoietin

What was the major regulatory concern with FlavRSavR tomato?

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"Agrobacterium tumefaciens, which could potentially cause disease in humans, was used to introduce the transgene"
"Agrobacterium tumefaciens, which could potentially cause disease in farm animals, was used to introduce the transgene"
Agrobacterium tumefaciens which normally cause disease in plants was used to introduce the transgene
The engineered enzyme is potentially allergenic
The engineered enzyme might cause indigestion

Agrobacterium tumefaciens which normally cause disease in plants was used to introduce the transgene

"Which is not a major concern with xenotransplantation, or the use of animal organs in humans?" \n \n Some animal organs contain unhealthy levels of cholesterol \n Possible carry over of viral pathogens from the donor animal into the human recipient \n The transplanted animal organ is likely to get rejected by the human recipient's immune system \n Possible carry over of bacterial pathogens from the donor animal into the human recipient \n Receiving an animal organ or tissue is against some patients' religious beliefs

Some animal organs contain unhealthy levels of cholesterol

What is the main difference of modern from classical biotechnology? \n \n Modern involves the use of computers to improve plants \n Modern involves recombinant DNA technology while classical does not \n Modern involves the use of technology to improve humans \n Modern involves selective breeding while classical does not \n Modern involves fermentation while classical does not

Modern involves recombinant DNA technology while classical does not

What was the main concern with the engineering of Bt toxin gene in crop plants? \n \n The Bt toxin may lead to herbicide resistant superweeds \n The Bt toxin may kill the plant \n The Bt toxin can cause indigestion in browsing deer \n The Bt toxin may cause neurological disorders in humans \n The Bt toxin may kill beneficial insects

The Bt toxin may kill beneficial insects

"Vaccines against many diseases have been successfully produced in plants, including the rotavirus vaccine in alfalfa. In infected infants, rotavirus causes:" \n \n respiratory distress \n hepatititis \n constipation and bloating \n organ rejection \n dehydration and death

dehydration and death

What is one reason as to why earlier gene therapy clinical trials in humans had to be stopped by the Food and Drug Administration? \n \n One patient had uncontrolled bleeding \n A patient acquired a viral infection from the viral vector used \n Some patients refused to sign informed consent statements \n Some patients acquired a functional immune system \n A clinical trial participant died from hyperimmune response to the virus vector

A clinical trial participant died from hyperimmune response to the virus vector

"Vaccines against many diseases have been successfully produced in plants. Hepatitis B vaccine, to protect against hepatitis B virus, has been successfully produced in banana. What disorder does the Hepatitis virus cause?" \n \n Lung congestion \n Liver damage \n Kidney damage \n Foot and mouth disease \n Diarrhea and dehydration

Liver damage

What is true of endotoxins? \n \n A immunogenic substance produced by fungal pathogens of man \n Not a main concern if the drug contaminant is a Gram positive bacteria \n An immunogenic substance found in the outer wall of most Gram positive bacteria \n A drug contaminant that causes an out-of-control immune response in drugs that are formulated as syrups \n Not a main concern if the drug contaminant is a Gram negative bacteria

Not a main concern if the drug contaminant is a Gram positive bacteria