cellular function

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Pathology

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137 Terms

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plasma membrane

  • semipermeable

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  • selectively allows substances to move in and out of cell

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semipermeable

separates internal environment from external environment

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cellular edema

excess fluid enters cell

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cellular dehydration

fluid leaks out of cell

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lipid bilayer

channels that allow exchange of molecules and water

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nucleus

  • largest organelle in cell

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  • composed of nucleotides

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purines: adenine and guanine

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pyrimidines: cytosine and thymine

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ribosomes

  • site of protein synthesis (diff cells make diff proteins

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hypoxia: lack of oxygen

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Endoplasmic Reticulum (ER

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Smooth ER: lipid production

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Rough ER: protein and enzyme synthesis

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ER stress

decrease transport of proteins...rapidly degraded

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mitochondria

  • cell energy producer

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  • converts nutrients into ATP to cellular respiration

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aerobic metabolism

requires oxygen

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net yield: 34 ATP

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anaerobic metabolism

oxygen not available (cellular hypoxic

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net yield: 2 ATP

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Lysosomes

breakdown or digest material surrounded by cell (bacteria or viruses

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peroxisomes

breakdown free radicals

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Golgi apparatus

process, package, and secrete proteins

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microtubules

cilia and flagella ( hair like structure, aids in movement

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microfilaments

solid flexible fibers (help w cell movement

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selective permeability

cell wall allows some substances through the membrane while blocking others

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glucose

provides energy

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electrolytes

charged chemical conductors when dissolved

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enzymes

proteins that facilitate chemical reactions

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diffusion

movement of particles from an area of higher to lower concentration, requires NO energy

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simple diffusion

concentration gradient, stops when equal on both sides

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facilitated diffusion

something helps to move particles

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  • dependent on number of carrier molecules

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osmosis

only concerns movement of water

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low concentration to high concentration

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active transport

low concentration to high concentration

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  • requires a carrier molecule & energy

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endocytosis

bringing a substance or particle in cell by surrounding it in effort to get rid of

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phagocytosis

solid particle

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exocytosis

releasing a substance or particles from cell

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proliferation

cells divide and reproduce

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mitosis

one cell divides into two identical cells

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meiosis

requires a mature sperm and ova

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differentiation

occurs w meiosis

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  • cells become more specialized

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  • forms tissues into organs

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stressors

  • bacteria, extreme heat or cold, alcohol, smoke, chemicals

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  • response of cells = bacteria causes inflammation, swelling

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adaptive changes

compensate and attempt to maintain homeostasis

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maladaptive changes

alter the structure and function of cell

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atrophy

cells become smaller

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hypertrophy

cells increase in size

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physiological hypertrophy

cell enlargement w adequate supporting tissues

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pathological hypertrophy

increase in cell size, w/o increase in support structures

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hyperplasia

increase in number of cells

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  • hormonal stimulation, maladaptive compensation

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metaplasia

replacement of one cell type with another