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approximately how many women die each year in the US as a result of pregnancy or delivery complications?
700
the US is one of how many countries in which maternal mortality rates have been on the rise in recent years?
8
what are the leading causes of maternal mortality?
severe bleeding, infection/sepsis, cardiovascular conditions, blood pressure disorders, substance use/mental health
t/f: most maternal mortalities are preventable
true
what is the definition of infant mortality?
the death of an infant before his or her first birthday
how many infants died in the US in 2020?
20,000
what were the five leading causes of infant death in 2020?
maternal pregnancy complications, birth defects, preterm birth, SIDS, injuries
the US is ranked what out of 38 in infant mortality rates compared to similarly developed countries?
33
what determines an individual’s sex?
chromosomes, hormones, and reproductive organs
what is the definition of identity?
the internal perception of one’s gender
what is the definition of attraction?
sexual and romantic feelings
how much more likely are black women likely to die in childbirth?
3-4
what socioeconomic factors are rooted in systemic racism and negatively impact reproductive healthcare of black women?
access to prenatal care, insurance coverage, education, income, and quality of hospital care
what are negative impacts of systemic racism and provider bias?
pain isn’t taken seriously, the patient is ignored, and they may experience physical/verbal abuse
what is the definition of reproductive justice?
the human right to bodily autonomy as well as the freedom to make one’s own decisions regarding sexuality, gender, relationships, having children, and raising children in safe and equitable communities
what regulates the reproductive cycle?
sex hormones
what cycles compose the reproductive cycle?
ovarian cycle and the menstrual (uterine/endometrial) cycle
the reproductive cycle ends in one of what two possibilities?
pregnancy or menstruation
gonadotropin releasing hormone stimulates the release of which hormones?
follicular stimulating hormone (FSH) and luteinizing hormone (LH)
what hormones cause the endometrium to thicken and prepare to support a pregnancy?
estrogen and progesterone
what do maturing follicles release?
estrogen
in which phase does the follicle degenerate into corpus luteum after ovulation and egg is released?
luteal phase
what releases progesterone?
the corpus luteum
what are the phases of the ovarian cycle?
follicular phase, ovulation, luteal phase
what is the definition of contraception?
a method or device used to prevent pregnancy that works to block fertilization or implantation
t/f: there is a “best” form of contraception
false
hormonal contraception is centered around what?
estrogen and progestin
what is the mechanism of action for hormonal contraception?
thickens cervical mucus, thins the uterine lining, and prevents ovulation
what are the advantages of hormonal contraception methods?
no effect on future fertility, relieves PMS, lighter periods, can be used to treat PCOS, and reduces acne
what are the disadvantages of hormonal contraception methods?
need a prescription, not effective against STIs
what are side effects of hormonal contraception methods?
nausea, breast tenderness, mood swings, weight gain, headaches
what is the main adverse effect of hormonal contraception methods?
blood clots
what are contraindications of hormonal contraception methods?
hypertension, being a smoker over 35, history of DVT/PE/stroke
in terms of contraception, what is a ring and how does it work?
a silicone based flexible ring that is placed in the vagina for three weeks and is removed during the fourth week, releasing combined hormones slowly and locally
in terms of contraception, what is a patch and how does it work?
a patch is placed on the arm, back, buttocks, or abdomen for three weeks and left off for the fourth week, getting absorbed by fat and circulated systemically
in terms of contraception, what is the pill and how does it work?
a progestin only pill that needs to be taken at the same time every day
what is a combination pill for contraception?
21 combined hormone containing pills and 7 placebo pills that need to be taken at the same time daily
in terms of emergency contraception, what is an implant?
a hormone containing flexible rod requiring medical insertion/removal placed via a small incision that lasts up to 3 years
in terms of contraception, what is an intrauterine device?
long term pregnancy prevention
what are examples of barrier methods of contraception?
female condoms, condoms, diaphragm, cervical cap, cervical sponge
what are surgical methods of contraception?
tubal ligation and vasectomy
what are natural methods of contraception?
calendar, cervical secretions, thermal, withdrawal, abstinence
what is the definition of gestational age?
the age of the pregnancy, beginning with the first day of the last menstrual period
what is the definition of developmental age?
the age of the fetus, starting with the date of conception
what are the three developmental stages of a fetus?
pre-embryonic, embryonic, and fetal
when does the pre-embryonic stage occur?
weeks 0-1 of pregnancy
when does the embryonic stage occur?
weeks 2-8 of pregnancy
when does the fetal stage occur?
weeks 9-38 of pregnancy
what occurs during the pre-embryonic stage of development?
implantation
what occurs during the embryonic stage of development?
organogenesis
what occurs during the fetal stage of development?
rapid growth/development
what key milestone occurs in weeks 5-6 of pregnancy?
fetal heartbeat becomes detectable
what key milestone occurs in week 8 of pregnancy?
organogenesis complete
what key milestone occurs in week 16 of pregnancy?
quickening
what key milestones occur in week 24 of pregnancy?
viability, surfactant
what are the three key roles of the placenta in pregnancy?
circulation, protection, and hormone production
how does the placenta promote circulation to the fetus?
delivers oxygen/nutrients from the pregnant person’s bloodstream into the fetus and removes carbon dioxide and cellular waste
how does the placenta protect the fetus?
transfers the gestational parent’s immunoglobulins that will provide passive immunity to the fetus
how does the placenta impact hormone production?
serves as a temporary endocrine gland
what is the definition of oligohydramnios?
too little amniotic fluid in the amniotic sac
what is the definition of polyhydramnios?
too much fluid in the amniotic sac
what is the vasculature of the umbilical cord?
one large vein and two smaller arteries
what is wharton jelly?
a gelatinous substance surrounding the umbilical vessels which helps the cord slide back and forth and preventing compression of the cord
what is the function of human chorionic gonadotropin (hCG)?
signals corpus luteum to continue producing estrogen and progesterone, which is eventually taken over by placenta
what is the function of progesterone?
facilitates implantation, breast development, metabolism, and decreases uterine contractility
what is the function of estrogen?
facilitates implantation, breast development, uterine/placental growth and blood flow, and increased uterine contractility
what is the function of human chorionic somatomammotropin (hCS0 or human placental lactogen (hPL)?
stimulates lactation and increases metabolism and insulin resistance
what is the function of relaxin?
facilitates implantation, softens the cervix for delivery, relaxes pelvic joints, and increases blood circulation
what are the components of family planning?
the decision to have children, the decision of when to have children, the ability to raise children in a safe environment, and planning before contraception
what are the two key types of unintended pregnancies?
the pregnant person never wanted to be pregnant (unwanted) or they didn’t want to be pregnant this early or at this time (mistimed)
what are the options for unintended pregnancies?
abortion/termination, carry to term and parent, carry to term and give up for adoption
what is the definition of an abortion?
termination of a pregnancy
what is the definition of induced abortion?
termination of a pregnancy through an intervention guided or performed by a healthcare provider
what is the definition of spontaneous abortion?
loss of a pregnancy before the 24th week of pregnancy (miscarriage)
when did abortion initially become illegal in the US?
between 1860 and 1880
when did Roe v Wade federally protect a person’s right to an abortion?
1973
when did Dobbs v Jackson Women’s Health Organization leave the legality of abortions up to the states?
2022
how many abortions were performed in the US in 2023?
just over 1 million
what percentages of abortions performed in the US in 2023 were “abortion by pill”?
63%
what ratio of people capable of pregnancy receive abortions before the age of 45?
1 in 4
who needs jucicial bypass to receive an abortion?
minors
what are complications to outpatient abortion care?
gestational age, bleeding disorders, BMI, previous OB complications, poorly controlled chronic conditions (HTN, DM, SCD), and untreated psychiatric illness
abortion by pill is done using what two medications?
mifepristone and misoprostol
what is the first pill offered in medication abortion?
mifepristone
what are contraindications for mifepristone?
adrenal insufficiency, bleeding disorders, and long term steroid use
what are possible side effects of mifepristone?
nausea/vomiting, abdominal cramps, and potential spotting
what are possible side effects of misoprostol?
nausea, diarrhea, chills, rigors, and fever
up until what gestational age are patients eligible for medication abortion?
10.0 weeks, but some facilities offer up until 11.6 weeks
what is the advantage of a medication abortion compared to a procedural abortion?
less invasive
what medications should a patient take prior to a medication abortion?
anti emetics and NSAIDs 30 minutes before
what can a patient expect after receiving a medication abortion?
bleeding can be intense but is short lived, contractions until pregnancy is passed, and patients may see the pregnancy when it is passed
following a medication abortion, clots should not be larger than what?
a lemon
how much blood following a medication abortion warrants concern?
2 fully saturated pads in an hour for two hours
how long after a medication abortion should the patient follow up with the provider?
7-14 days
what is a manual vacuum aspiration (MVA) procedural abortion?
uses handheld suction to remove the pregnancy
at what gestational age can a manual vacuum aspiration be performed?
5-12 weeks
what is a dilation and evacuation (D+E) procedural abortion?
the cervix is gently opened and the uterine lining is scraped with all tissue removed
at what gestational age can a dilation and evacuation be performed?
13-16 weeks
how long can a dilation and evacuation take?
two days; dilators placed overnight and uterine evacuation the next day
what are possible complications of procedural abortions?
bleeding, infection, damage to the uterus, incomplete abortion