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Central Nervous system (CNS)
brain and spinal cord
Peripheral Nervous System (PNS)
cranial nerves (12 prs), spinal nerves (31 prs)
Neurons
highly specialized structures that receive, process, and transmit information to, from, and within the nervous system
How do neurons function?
They are wrapped together in bundles that form nerve pathways or tracts
Afferent Nerves
Ascending - bringing sensory information to brain, and carry information from sensory receptors
Efferent Nerves
sending motor commands out from brain
Mixed nerves
Some afferent nerves, some efferent nerves bundled together
Interneurons
within the nervous system (communication)
Dermatome
Area of body served by a spinal nerve
Teleceptors
sensory information from distant environment
Eye, Ear
Proprioceptors
position of body in space
Inner ear, muscles, tendons, joints
Chemoreceptors
taste, smell
tongue, nose
Mechanoreceptors
pressure/deformation
tissue, inner ear
Which cranial nerves are used for speech?
Trigeminal Nerve (CN V)
Facial Nerve (CN VII)
Vestibulocochlear
Glossopharyngeal Nerve (CN IX)
Vagus Nerve (CN X)
Hypoglossal Nerve (CN XII)
Trigeminal nerve function
sensory: face
motor: chewing
Facial nerve function
motor: facial expression, sensory: taste
Vestibulocochlear nerve function
sensory: hearing motor: damping for muscles
glossopharyngeal nerve function
Sensory: back of the mouth motor: pharynx
Vagus nerve function
Senory and motor for the body
Hypoglossal Nerve (CN XII)
Controls tongue muscles, which are essential for articulation and speech
dendrites
receive stimuli
soma
generates AP at Axon hillock
axon
transmits impulses
Terminal end button
Synapse
The synapse
junction/space
presynaptic neuron
conducts impulses toward the synapse
synaptic cleft
The narrow gap that separates the presynaptic neuron from the postsynaptic cell.
postsynaptic neuron
transmits impulses away from the synapse
Neurons at rest are
NEGATIVE
How do neurons keep this negative attitude?
Na/K pump is trying to maintain this negative attitude
moves 3 Na IN and 2 K OUT
Electrical synapse
Faster, direct connection of cytoplasms
Less common
Retina, olfactory, cortex
Chemical Synapse
most common, and use neurotransmitters
2 hemispheres of the brain
right and left, cortex/subcortex
brainstem
midbrain, pons, medulla
cerebellum
A large structure of the brain that controls fine motor skills
gray matter (cerebral cortex)
outermost area of the cerebral hemispheres that contains the cell bodies of neurons
LEFT hemisphere
language & Broca's area for speech production
What parts of the brain are involvedin speech and language?
Perisylvian areas, bilaterally
Frontal lobe
motor strip
Broca's area
speech production -formulates language, then sends to motor strip to execute language
Motor strip
muscle movement, voluntary movement
White matter
Blood Supply to the Brain
Middle Cerebral Artery
nutrients to many speech areas
Blood-brain barrier
Keeps brain safe
Astrocytes
take glucose from blood & deliver it to neurons
Oxygen diffuses into CSF
Functional MRI
Functional MRI shows regional cerebral blood flow, where is blood going in the brain
EEG & ERP
Event-related potentials (ERP)
Measure of electrical activity of brain over time, via electrodes on skull
Neurogenic Conditions impacting speech/language
Parkinson's Disease (PD)
Multiple Sclerosis (MS)
Amyotrophic Lateral Sclerosis (ALS)
Alzheimer's Disease
Cerebral Palsy
Traumatic Brain Injury
Motor speech disorders
Dysarthria, Apraxia, Aphasia
Dysarthria
impaired speech production due to motoric disability
Apraxia
impaired speech production despite motoric ability
Aphasia
Impaired speech/language following brain damage CVA (stroke), head trauma, tumor
Respiration
gas exchange between an organism and its environment
speech production requires airstream
Vertebrae
Cervical, thoracic, lumbar, sacrum, coccyx
Pectoral girdle
Clavicle, scapula
Pelvic girdle
illium, ischium, pubis
Soft Tissues
Trachea and bronchial tree
Lungs (asymmetrical, 2 left, 3 right)
Muscles Of Inspiration
diaphragm and external intercostals
Forced expiration
abdominals
Pleural linkage
visceral and parietal with space for pleural fluid
Intrapleural pressure is negative
the lungs are LINKED - they are lifted even though the muscles don't touch them
VC at Rest (automatic)
10%
Boyle's Law
volume is the inverse of pressure
Respiratory measures
Adequate airflow required for normal speech production Spirometer
Inspiratory Muscle Function
diaphragm
lung expansion
Primary muscle of INSPIRATION
Intercostals
Boyle's law (negative pressure, air comes in)
Expiratory Muscle Function
Life breathing: passive - relies on gravity, muscles relaxing, elastic recoil
Speech Breathing
10% inspiration, 90% expiration
Respiratory Pressures
Adequate air pressure required for normal speech
Life breathing
exhalation is passive, but is too fast for making speech
Speech breathing
controlled recoil (checking forces to make sure lungs don't deflate too quickly)
Resting Expiratory Level (REL)
Refers to a state of equilibrium in the respiratory system
Conditions Affecting Speech Breathing
-Aging
-Increased ossification of costal cartilages
-Decreased strength of respiratory muscles
-Loss of alveolar surface tenson
-Decreased lung size
Spastic CP
-HYPERtonic & weak
-shallow inhalations
-forced/uncontrolled expiration
Athetoid CP
- Involuntary movements
- irregular/uncontrolled breathing
Respiratory Disorders
COPD (chronic obstructive pulmonary disease) Difficulty breathing due to bronchitis and/or emphysema
CF (cystic fibrosis) Genetic disorder that primarily affects lungs & breathing
Neuromuscular Disorders
ALS (amyotrophic lateral sclerosis) - death of neurons
Myasthenia gravis - neuromuscular disease; muscle weakness
Spinal cord injury - changes in function (e.g., loss of muscle function)
spinal accessory
larynx and motor muscle near spine
depolarization
The process during the action potential when sodium is rushing in (charge changes) the cell causing the interior to become more positive.
repolarization
Return of the cell to resting state, caused by reentry of potassium into the cell while sodium exits the cell. (Na/K pump)
Synapse
where the nuerotransmitters cross
Neurotransmitters
chemical messengers that cross the synaptic gaps between neurons
dendrite
the bushy, branching extensions of a neuron that receive messages and conduct impulses toward the cell body
How many sodium in and potassium out
3 Na in, 2 K out
action potential
a neural impulse; a brief electrical charge that travels down an axon
Things to talk about in action potential
synapse, neurotransmitter, dendrite, Na/K, depolarization, and repolarization
Pleural Linkage
Result of the 2 pleural linings of the lungs that are attached to other parts that pull the lungs down
visceral pleura
inner layer of pleura lying closer to the lung tissue
parietal pleura
outer layer of pleura lying closer to the ribs and chest wall
How does pleural linkage work?
Visceral (inner) and partial lining (outer) are surrounding the lung, the diaphragm is touching the pariteal lining, the diaphram is going to flatten and pull the lungs down, and volume is going to increase. Boyle's law=pressure and volume are inverse, and air will come in
Life breathing the diaphragm is
relaxing, passive, air pushes out
Speech breathing the diaphragm is
using muscles
Expiratory Muscle Activity (rest, speaking, singing)
Rest: passive (muscles relaxing)
Speaking/Singing: muscle activity
Lung volume % of vital capacity (rest, speaking, singing)
Rest: 10% at VC
Speaking: 25% of VC
Singing: 40% of VC
Inspiration/expiration % (rest, speaking, singing)
Rest: 40% Inspiration, 60% expiration
Speaking/Singing: 10% Inspiration, 90% expiration
Body part at rest air intake
nose
Speaking/singing air intake body part
mouth
CT vs MRI
CT: better at detecting bone, quick, less expensive, xray
MRI: better at detecting soft tissue diseases, long, magnetics
Both brain imaging, used for diagnosis, used in acute phase
Lobes and divisions of the brain functions
Frontal Lobe – Thinking, decision-making, voluntary movement, speech (Broca’s area), personality
Parietal Lobe – Touch, temperature, pain, spatial awareness
Temporal Lobe – Hearing, language (Wernicke’s area), memory, face/object recognition
Occipital Lobe – Vision (color, shape, motion)
Cerebellum – Balance, coordination, motor learning
Brainstem – Breathing, heart rate, digestion
blood-brain barrier
Network of cells (gliall cells) that let certain substances enter the brain tissue and keep other substances out