What term is used to describe continuous tonic-clonic seizures, lasting over 30 minutes, with high fever, and during which consciousness may not return?
status epilepticus
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2
What is a common side effect of pyridostigmine (Mestinon) for myasthenia gravis?
salivation
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3
Which of the following multiple sclerosis medications must be stored in the refrigerator and brought to room temperature for administration?
glatiramer acetate
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4
what is one of the major ways in which antiepileptic medications can interact with each other and with other drugs
They can displace drugs from their binding sites on plasma proteins.
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5
What drug blocks glutamate receptors in patients who have Alzheimer's disease?
memantine
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6
What class of drugs may be used to diagnose and treat myasthenia gravis?
acetylcholinesterase inhibitors
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7
Which of the following drug classes is used to treat mild symptoms early in Alzheimer's disease?
acetylcholinesterase inhibitors
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8
Which of the following anticonvulsants is a controlled substance?
phenobarbital
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9
what drug is both a prophylaxis and treatment for influenza as well as Parkinson’s disease?
amantadine
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10
What are the two neurotransmitters in the brain that play the greatest role in seizures?
GAGA and Glutamate
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11
Which of the following is not true regarding the medication phenytoin?
used to manage neuropathic pain
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12
Carbamazepine has a boxed warning for potentially fatal dermatologic reactions for which of the following population groups?
Asian parients
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13
Methylphenidate, an agent used to treat children with ADD/ADHD, can best be characterized as a(n)
stimulant
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14
What combination drug contains levodopa plus an inhibitor of peripheral levodopa metabolism?
Sinemet
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15
Patients and providers must complete risk-benefit evaluations to manage epilepsy during pregnancy with which of the following drugs?
topiramate
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16
Which anti-Parkinson's agent is associated with the on-off phenomenon?
levodopa
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17
Which is a new class of anti-Parkinson agents that increases patient "on" time?
catechol-o-methyl transferase inhibitors
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18
Which of the following anticonvulsants is also used to treat manic episodes in bipolar mood disorders?
valproate
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19
Which of the following Alzheimer's disease drugs is commercially available as a transdermal patch under the brand name Exelon?
memantine
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20
Which of the following anticonvulsant drugs is a GABA enhancer?
pregabalin
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21
Which of the following is an over-the-count product thought, but not conclusively proven, to improve memory for patients with Alzheimer's disease
ginkgo biloba
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22
Drug therapy for multiple sclerosis seeks to
slow down the progression of the disease
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23
What is the most common drug therapy for the treatment of Parkinson's disease?
levodopa
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24
Which of the following is a self-injected agent used for acute treatment of intermittent "off" time during the treatment of Parkinson's Disease?
apomorphine
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25
Patients who are taking rasagiline should be advised to avoid which of the following types of food?
those that contain tyramine
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26
The use of which anticonvulsant may result in physical or psychological dependence?
pregabalin
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27
Bromocriptine is a drug often prescribed for patients with a diagnosis of
Parkinson’s disease
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28
Which drug used to treat ADD/ADHD is not a controlled substance?
atomxetine
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29
Carbamazepine is a drug used to control seizures and is also used in the treatment of
bipolar disorder
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30
Which of the following drugs reduces the release of glutamate, norepinephrine, and substance P?
pregabalin
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31
Which of the following is a goal of antiepileptic drug therapy?
reduce the frequency of seizures
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32
Which of the following drugs was originally developed to improve cognition and is not structurally related to other anticonvulsants?
levetiracetam
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33
Which of the following anticonvulsant drugs is also used to prevent migraines?
topiramate
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34
Fosphenytoin is rapidly converted to which of the following drugs upon administration?
phentyoin
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35
Which of the following medications used to treat Parkinson's disease can discolor a patient's urine to a red, brown, or black color?
entacapone
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36
All of the following are side effects from taking the medication cyclophosphamide, except
increased appetite
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37
What is the cause of a seizure?
excessive firing of neurons
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38
Which of the following anticonvulsant drugs can also be used for shingles, fibromyalgia, hot flashes, hiccups, restless legs syndrome, and diabetic neuropathy?
gabapentin
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39
The CNS stimulants all have boxed warnings for the potential of
dependence
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40
Lamotrigine has a boxed warning about the possibility of which of the following?
fatal rashes
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41
Which of the following drugs is not a commonly used agent for myasthenia gravis?
dopamine
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42
What is the mechanism of action for anticholinergics drugs?
blocking muscarinic receptors in the brain
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43
Which of the following conditions is an autoimmune disease characterized by the degeneration of myelin sheaths around nerves, which serve as electrical insulation?
multiple sclerosis
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44
Which of the following conditions is a disorder of the interface between nerves and muscles, resulting from autoimmune damage to acetylcholine receptors at the motor end plate?
myasthenia gravis
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45
Which of the following conditions is a degenerative disorder of the brain that leads to progressive dementia and changes in personality?
alzeimer’s disease
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46
The FDA has issued a boxed warning for tiagabine about which of the following problems?
the ability to cause seizures
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47
Due to serious adverse effects, which anticonvulsant requires the patient or guardian to sign informed consent to use?
felbamate
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48
Due to the \_____, the small allowable differences in manufacturing can affect the effectiveness of anticonvulsants.
narrow therapeutic index
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49
Patients who use a catechol-O-methyltransferase inhibitor typically
may reduce the dosage of levodopa.
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50
What is required to be dispensed with all antiepileptic drugs?
medication guide
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51
Which of the following alternative therapies is used in patients with Parkinson's disease to improve motor symptoms?
5-hydroxytryptophan
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52
Which of the following anticonvulsants should not be given to a patient with a sulfa allergy?
zonisamide
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53
When levodopa crosses the blood-brain barrier, it is metabolized into which of the following neurotransmitters?
dopamine
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54
Patients with Parkinson's disease have an imbalance of which of the following neurotransmitters?
dopamine and acetylcholine
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55
Common therapy for children and adults with attention-deficit/hyperactivity disorder include the use of which of the following?
CNS stimulants
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56
If a patient is taking methylphenidate for ADHD, which of the following drug classes should be avoided by the patient for the two weeks prior to starting therapy?
MAOIs
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57
Gingival hyperplasia is a hallmark side effect of which anticonvulsant drug?
phenytoin
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58
Certain drugs should not be taken within two weeks prior to the initiation of an MAOI. This time interval is known as the
washout peroid
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59
Which of the following medications must have blood levels drawn within 5 to 10 days after the start of therapy to ensure therapeutic doses are being given?
lithium
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60
Cyclic antidepressants are sometimes used for which of the following side effects?
sedation
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61
\_____ is an antipsychotic drug that has a ceiling dose. Doses exceeding 800 mg can cause pigment deposits in the retina, sometimes leading to blindness.
Thioridazine
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62
Given an example of an anxiety drug
buspirone
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63
What is the term used to describe involuntary movements of the mouth, lips, and tongue that are sometimes accompanied by involuntary movements of the limbs or trunk?
tardive dyskinesia
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64
If a patient is taking phenelzine, they should avoid all of the following except
fresh shellfish
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65
All SSRI drugs are contraindicated with the use of which of the following drug classes?
MAIOs
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66
Which of the following serotonin and norepinephrine reuptake inhibitor drugs is available for hot flashes, fibromyalgia, and neuropathic pain?
desvenlafaxine
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67
three examples that are controlled substances used to treat insomnia
temazepam, eszopiclone, triazolam
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68
Which of the following antidepressants is a dopamine and norepinephrine reuptake inhibitor with no direct effect on serotonin or monoamine oxidases?
bupropion
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69
The serotonin and norepinephrine reuptake inhibitor Cymbalta, carries an indication for the treatment of both depression and
pain
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70
Paliperidone uses an extended-release technology called osmotic controlled-release oral delivery system. What should patients be made aware of in regard to this technology?
ghost tablets in the stool
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71
Which of the following psychiatric disorders is characterized by feelings of pessimism, worry, intense sadness, loss of concentration, slowing of mental processes, and problems with eating and sleeping?
depression
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72
An overdose of TCAs may result in CNS toxicity and
potentially fatal cardiac arrhythmias.
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73
Which of the following drugs is not a cyclic antidepressant?
trazodone
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74
Which of the following drugs is an antipsychotic?
clozapine
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75
An initial prescription of Zyban for smoking cessation should be dosed as
once daily for 3 days
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76
Modafinil is a nonamphetamine, Schedule IV drug approved for which of the following conditions?
shift-work disorder
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77
Which of the following drug classes have anticholinergic side effects, which may decrease urinary urgency?
TCA’s
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78
Which of the following drugs is an anticholinergic drug that may produce an immediate, but not necessarily complete, response to excess muscle activity resulting from antipsychotic drug administration?
benztropine
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79
Which of the following classifications of drugs inhibit the activity of the enzymes that break down catecholamines?
MAOI’S
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80
Wellbutrin XL should be used with caution in patients with a history of which of the following conditions?
seizures
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81
Zoloft and Zocor may be mistaken for one another. Zoloft is used to treat \_____ and Zocor is used to treat elevated cholesterol levels.
depression
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82
Which of the following drugs is used for depression, Parkinson's disease, and Alzheimer's disease and is available as a transdermal patch?
selegiline
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83
Which herbal supplement should not be used with other antidepressants due to an increased risk of serotonin syndrome?
St. Johns Warts
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84
The primary indication for using antipsychotic drugs is to treat which of the following conditions?
schizophrenia
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85
The drug lorazepam used to treat anxiety is classified as a controlled substance schedule in which of the following schedules?
Schedule IV
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86
Which of the following drugs is classified as an SSRI?
Sertraline
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87
The antidepressant \_____ should be used with caution in patients taking over-the-counter ginkgo biloba due to the possibility of serious interactions.
trazadone
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88
Which of the following is a serious side effect of clozapine drug therapy, making it necessary for the dispensing pharmacist to review blood levels?
reduction in white blood cells
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89
Which of the following is a pure opiate antagonist that blocks the effects of endogenous opioids released as a result of alcohol consumption?
natrexone
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90
Prozac and Proscar are "look-alike and sound-alike" medications and are, therefore prone to error. Prozac is used to treat \_____ and Proscar is used to treat \_____.
depression; enlarged prostate
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91
Which of the following tricyclic antidepressants is available as a cream used to treat pruritus (itching) in adults and geriatric patients?
doxepin
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92
Celexa is often confused with Cerebyx and Celebrex, therefore, caution must be used in dispensing. Celexa is used to treat \_____, while Cerebyx is an anticonvulsant, and Celebrex is used to treat arthritis.
depression and OCD
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93
What drug class is often used for the detoxification process for alcohol overdose?
benzodiazepines
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94
What term is used to describe a mood of hyperactivity, extreme excitement, and excessive elation?
mania
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95
Which of the following SSRIs is used to treat a severe form of premenstrual syndrome?
fluoxetine
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96
Low doses of prochlorperazine are commonly used for
nausea and vomiting
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97
Which two neurotransmitters are believed to be most involved with schizophrenia and the drugs used to treat this disorder?
dopamine and serotonin
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98
Fluoxetine is an example of an antidepressant that appears to work through which of the following mechanisms?
It inhibits the reuptake of serotonin in the brain.
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99
What is a common side effect from taking antipsychotic medications?
weight gain
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100
Which of the following drugs used to treat insomnia is a melatonin receptor agonist?
Studied by 2 people
