DNA Replication

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7 Terms

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4 main enzymes

  1. Helicase
  2. Primase
  3. DNA Polymerase
  4. Ligase
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Helicase

unzips DNA strands to start replication process

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Primase

sets down RNA primer for DNA polymerase to build off of

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DNA Polymerase

adds new nucleotides to make new strand

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Ligase

seals nucleotides together to complete strand

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Leading Strand

  • built 5' to 3' to replication fork (5' near un split area)

  • opening is opposite

  • built continuosly

  • RNA primer only applied at start

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Lagging Strand

  • built 3' to 5' to replication fork (3' near un split area)

  • opened opposite way

  • built in Okazaki fragments

  • RNA primer applied multiple times

  • fragments sealed together by ligase