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sarcolemma
plasma membrane of a muscle fiber
sarcoplasmic reticulum
smooth ER that forms a network around each myofibril:
Triad
a T tubule and two terminal cisterns associated with it
Thick filaments
made of several hundred myosin molecule, contains globular head
Thin filaments
Fibrous (F) actin: two intertwined strands
Tropomyosin and Troponin (Ca binding) molecules
Elastic filament
Titin: huge, springy protein
Run through core of thick filament and anchor it to Z disc and M line
Help stabilize and position the thick filament
Prevent overstretching and provide recoil
contractile proteins
myosin and actin
regulatory proteins
tropomyosin and troponin
Dystropin
Allows for muscle fiber shortening by connecting sarcomere and endomysium
Small motor units
fine degree of control, eye and hand muscles
Large motor units
more strength than control, large muscles
resting membrane potential
about −90 mV in skeletal muscle cells
tetanus
lockjaw) is a form of spastic paralysis caused by toxin Clostridium tetani
flaccid paralysis
a state in which the muscles are limp and cannot contract
botulism
type of food poisoning caused by a neuromuscular toxin secreted by the bacterium Clostridium botulinum
length-tension relationship
the amount of tension generated by a muscle depends on how stretched or shortened it was before it was stimulated
rigor mortis
hardening of muscles and stiffening of body beginning 3 to 4 hours after death, peaks 12 hours after.
Isometric contraction
muscle contraction (“same length”)
Ex) holding a weight
Isotonic contraction
muscle contraction (“same tension”)
Ex) lifting a weight
anaerobic fermentation
Enables cells to produce ATP in the absence of oxygen
Yields little ATP and lactate, which needs to be disposed of by the liver
Myokinase
P + ADP → ATP
Creatine Kinase
P + Creatine phosphate → ADP → ATP
Slow twitch fibers
-Endurance, resists fatigue
-Deep red color (myoglobin)
-posture muscles
Fast twitch fibers
-Powerful muscles
-White color
-eye & hand & leg muscles
peristalsis
waves of contraction brought about by food distending the esophagus or feces distending the colon
Fusiform muscle
intermuscular septa
very thick fascia that separate one compartment from another
intrinsic muscle
entirely contained within a region, such as the hand
extrinsic muscle
acts on a designated region, but has one attachment elsewhere
synergist
muscle that aids the prime mover