DNA is copied so it can leave the nucleus to make proteins
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rRNA
DNA found in ribosomes
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ribosomes
responsible for protein synthesis (assembling proteins)
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Endoplasmic reticulum (ER)
after proteins are made, they are modified and transported to ER
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Rough ER
ER that is dotted with ribosomes
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Smooth ER
\`ER that has no ribosomes, responsible for synthesizing lipids\`
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Cytoskeleton
protein that provides support and movement within cell
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microtubules
hollow cylinders movement of chromosomes during cell division and in structure of cilia and flagella
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MTCOs
microtubule organizing center microtubules grow outward to assist in movement of chromosomes to two new cells
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centrioles
assist in microtubule assembly, inside centrosomes, form a hollow cylinder
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microfilaments
actin and myosin cause construction of cell to form two daughter cells cause muscle contraction
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cell coat
made up of polysaccharides side chains, glycoproteins, lipids
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cell wall
found in plants and bacteria bacteria \= thick \= purple \= positive plant \= red \= thin \= negative
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Fluid Mosaic Model
membrane is a phospholipid bilayer where proteins are embedded
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What are the cell membrane components?
Lipids and Proteins
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Amphipathic phospholipids
lipid bilayer with hydrophilic heads and hydrophobic tales
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Cholesterol
stabilizer during high temperature to restrict movement\`
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Peripheral proteins
only on one side
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Integral proteins
pores, channels, proteins that go all the way through the membrane
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Selective permeability
allows only certain materials to pass through membrane
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Diffusion
a passive transport, concentration gradient from high conc. to low conc. \`
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Active transport
requires energy expenditure, energy needed to move from low conc. to high conc., moved against conc. gradient
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What are the special methods of active transport?
Endocytosis and exocytosis
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Osmosis
diffusion of water
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Isotonic
equal amount of solute inside and outside the membrane
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Hypertonic
more solute outside the cell, cell loses water and shrinks
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Hypotonic
More solute inside the cell, cell will swell and burst
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Facilitated Diffusion
* an integral carrier protein binds to a molecule and releases it -to the other side
OR
* (POLAR) protein changes shape, opening a channel for movement across membrane
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Sodium Potassium Pump
maintains electrical imbalance, pumps sodium out and potassium in
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\ Exocytosis
removing item from cell
* “exo” = exit * biomacromolecule is enclosed inside a vesicle, which fuses with the cell membrane, ejecting the molecule from the cell
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Endocytosis
bringing molecules in
* “endo” = in * biomacromolecule outside the cell is enclosed in an invagination of membrane, forming a vesicle inside the cell
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Phagocytosis
* white blood cells use this * pseudopods pinches particle and encloses molecule inside a vesicle * vesicle detaches from membrane forming a phagosome * phagosome and lysosome fuse together * lysosome spits out debris
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Pinocytosis
“Cell drinks” tiny droplets of fluid
* no pseudopods (“arms”) * membrane invaginates to form a cup * forms vesicle from cup * vesicle releases solute
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Receptor-mediated endocytosis
On top of membrane, there are pits of receptors
* receptor proteins in membrane bind with signaling molecule * edges of pit come together to form vesicle * vesicle pinches off from membrane * vesicle merges w organelle called endosome * vesicle splits into two vesicles * vesicle w outside molecule goes to lysosome for digestion * when ligands binds to receptor, it changes shape * releases ATP energy