Chapter 13: RNA and Protein Synthesis

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Duplication

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62 Terms

1

Duplication

A mutation that occurs when an extra copy of all or part of a chromosome is made

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2

Translocation

A mutation that occurs when part of one chromosome breaks off and attaches to another one

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3

MicroRNAs

________ attach to mRNA molecules and stop them from passing on their protein- making instructions.

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4

Inversion

A mutation that occurs when parts of a chromosome change direction

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5

Master control genes

________ are like switches that trigger particular patterns of development and differentiation in cells and tissues.

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6

Genes

________ are made of instructions coded into DNA that tell cells how to build proteins.

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7

Metamorphosis

________ involves a series of changes from one life stage to another and is usually regulated by factors inside and outside of the body.

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8

Deletion

A mutation that occurs when part or all of a chromosome is lost

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9

DNA sequence

An insertion adds a new base to the ________, and a deletion removes a base from the ________.

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10

tRNA

The ________ molecules bring the correct amino acid for each codon on the mRNA.

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11

Proteins

Are made of long chains of amino acids called polypeptides

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12

rRNA

The ________ and many proteins make up the ribosomes.

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13

eukaryotes

In ________, transcription occurs in the cells nucleus.

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14

lactose

When ________ is present, it binds to the repressor, causing the release of the repressor, which then moves away from the operator; transcription can then take place.

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15

Temperature

________ and population size can also affect the speed of metamorphosis.

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16

Translation

A process by which the sequence of bases of an mRNA is converted into the sequence of amino acids of a protein; it is the decoding of an mRNA message into a protein

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17

RNA

________ is usually single- stranded and not double- stranded.

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18

Anticodon

A group of three bases on a tRNA molecule that are complementary to the three bases of a codon of mRNA

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19

transcription

During ________, the enzyme RNA polymerase uses one strand of DNA as a template to put together nucleotides to make a strand of RNA.

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20

Ribonucleic acid

A single-stranded nucleic acid that contains the sugar ribose

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21

Gene expression

The way DNA, RNA, and proteins are involved in putting genetic information into action in living cells

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22

genetic code

Insertions and deletions are also called frameshift mutations because they shift the "reading frame "of the ________; this change can alter a protein so much that it can not do its job.

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23

tiny tools

Basically, proteins are ________, each one designed to build or run a part of a living cell.

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amino acids

The shape and function of a protein are determined by its ________ and their sequence.

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Transcription factors

________ control the expression of eukaryotic genes by binding DNA sequences in regulatory regions.

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hormones act

The ________ to regulate gene expression, which controls the speed of metamorphosis.

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codon AUG

The ________ acts as the "start "codon for protein synthesis.

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Environmental changes

________ are translated into hormonal changes.

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29

environmental factors

In all kinds of organisms, ________ like temperature can change gene expression.

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30

Mutations

________ can help or harm organisms, though most mutations have little or no effect on genes.

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discovery of RNAi

The ________ has made it possible for researchers to switch genes on and off by inserting double- stranded RNA into cells.

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RNAi technology

________ may also provide a way for medical scientists to turn off genes from viruses and cancer cells; RNAi may provide new ways to treat, and maybe even cure, diseases.

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mRNA molecule

The ________ carries the coded message that directs the process.

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34

Special codons

________ tell the cell where to start and stop translating RNA.

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35

RNA

________ contains four different bases: adenine (A), cytosine (C), guanine (G), and uracil (U), which are like the letters of a language called the genetic code.

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Metamorphosis

________ is another example of how organisms can alter gene expression in response to environmental changes.

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37

amino acid

Each word in the genetic code is three "letters, "or three bases; each three- base set is called a codon that specifies one ________.

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38

genetic code

The ________ is read three "letters "at a time.

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39

Mutations

________ that make changes in a single gene are known as gene ________.

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40

RNA

The sugar in ________ is ribose instead of deoxyribose.

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41

genetic code

The ________ is a code for making proteins; it is a collection of codons of mRNA, each of which directs the incorporation of a particular amino acid into a protein during protein synthesis.

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42

RNA

There are three main differences between ________ and DNA.

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43

RNA

________ contains uracil in place of thymine.

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44

RNA

Promoters are signals in the DNA that show ________ polymerase exactly where to begin making ________.

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45

RNA contains four different bases

adenine (A), cytosine (C), guanine (G), and uracil (U), which are like the letters of a language called the genetic code

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46

There are four types of chromosomal mutations

deletion, duplication, inversion, and translocation

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47

Messenger RNA

A type of RNA that carries copies of instructions for the assembly of amino acids into proteins from DNA to the rest of the cell

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48

Ribosomal RNA

A type of RNA that combines with proteins to form ribosomes

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Transfer RNA

A type of RNA that carries each amino acid to a ribosome during protein synthesis

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50

Transcription

The synthesis of an RNA molecule from a DNA template, or pattern

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51

Polypeptide

A long chain of amino acids that makes proteins

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52

Genetic code

A collection of codons of mRNA, each of which directs the incorporation of a particular amino acid into a protein during protein synthesis

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53

Codon

A group of three nucleotide bases in mRNA that specify a particular amino acid to be incorporated into a protein

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54

Mutation

A change in the genetic material of a cell

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55

Point mutation

A gene mutation in which a single base pair in DNA has been changed

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56

Frameshift mutation

A mutation that shifts the “reading frame” of the genetic message by inserting or deleting a nucleotide

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57

Mutagen

A chemical or physical agent in the environment that interacts with DNA and may cause a mutation

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58

Polyploidy

A condition in which an organism has extra sets of chromosomes

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Operon

In prokaryotes, a group of adjacent genes that share a common operator and promoter and are transcribed into a single mRNA

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Operator

A short DNA region, adjacent to the promoter of a prokaryotic operon, that binds repressor proteins responsible for controlling the rate of transcription of the operon

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61

RNA interference

The introduction of double-stranded RNA into a cell to inhibit gene expression

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62

Homeotic gene

A class of regulatory genes that determine the identity of body parts and regions in an animal embryo. Mutations in these genes can transform one body part into another

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