psychopathology exam II

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Last updated 7:35 PM on 3/26/26
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92 Terms

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Fear

  • Response to an immediate, real danger

  • Activates fight or flight

  • Serve adaptive functions, can become maladaptive

  • Panic attack: occurs when fear arises in absence of real danger

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Anxiety

  • Diffuse apprehension about possible future threats

  • Cognitive & anticipatory

  • Serve adaptive functions, can become maladaptive

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Maladaptive

  • Anxiety enhances learning & performance when mild

  • Prepares individuals to anticipate & manage future threats

  • Chronic or excessive anxiety becomes _____ & may lead to anxiety disorders

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Social Anxiety Disorder (SAD)

Marked fear of social situations due to concern of negative evaluation (29%)

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Social anxiety disorder

Core features of ______:

  • Fear of scrutiny or judgement

  • Avoidance of social situations

  • Distress in everyday interactions

Causes of ….

  • Cognitive bias

    • Negative interpretations of social cues

    • Memory recall biased toward negative evaluations

  • Biological factors

    • Behavioral inhibition as a temperament trait

    • Amygdala hyperactivity in response to negative facial expressions

  • Perceptions of uncontrollability

    • Childhood experiences of unpredictability

    • Leads to submissive & avoidant behaviors

Treatment of …

  • Cognitive-behavioral therapy (CBT)

    • Exposure to feared social situations

    • Cognitive restructuring to correct negative self-perceptions

  • Medication

    • SSRIs

    • Monoamine oxidase inhibitors

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Panic disorder

Recurrent, unexpected panic attacks (4.7%)

Symptoms …

  • Rapid heart beat

  • Sweating

  • Shortness of breath

  • Fear of losing control/dying

Biological causes …

  • Genetic contributions

    • Moderate heritability

    • Overlap with phobias & separation anxiety

  • Neurobiology

    • Overactive fear network involving the amygdala & locus coeruleus

    • Decreased GABA activity, leading to heightened anxiety

  • Neurotransmitters

    • Serotonin → regulate mood & anxiety

    • Norepinephrine → linked to panic attacks

Treatment of …

  • Cognitive-behavioral therapy

    • Cognitive reconstruction to correct catastrophic thoughts

    • Exposure to feared bodily sensations

  • Medication

    • SSRIs

    • Benzodiazepines (short term, risk for dependence)

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One, month

Diagnosis of panic disorder: At least ____ attack followed by a ____ to worry about future attacks or behavior change

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Agoraphobia

Fear & avoidance of situations where escape may be difficult (80-90%)

Triggers:

  • Public transport

  • Open spaces

  • Crowded places

  • Fear of experiencing a panic attack in public

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Generalized anxiety disorder (GAD)

Chronic, excessive worry about various aspects of life

Causes of …

  • Biological factors

    • Genetic predisposition

    • Neurotransmitter imbalance

    • Overactive corticotropin-releasing hormone system

  • Psychological factors

    • Low tolerance for uncertainty

    • Perceptions of uncontrollability & unpredictability

    • Childhood trauma may increase risk

    • Reinforcing properties of worry

Treatment of …

  • Cognitive-behavioral therapy

    • Focuses on identifying & reconstructing worry-related thoughts

    • Behavioral interventions → muscle relaxation & exposure therapy

  • Medication

    • SSRIs

    • Benzodiazepines

    • Buspirone

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GAD

Criteria for _____ …

  • Occurs more days than not for at least 6 months

  • Difficult to control worry

  • At least 3 of the following:

    • Restless or feeling on edge

    • Being easily fatigued

    • Difficulty concentrating

    • Irritability

    • Muscle tension

    • Sleep disturbances

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Body dysmorphic disorder (BDD)

Preoccupation with perceived physical defects not visible or minor to others; compulsive behaviors

Causes …

  • Genetic & neurobiological factors

    • Moderate heritability

    • Overactivity in orbitofrontal cortex & caudate nucleus

  • Cognitive factors

    • Biased attention towards appearance-related stimuli

    • Distorted perception of facial symmetry

    • Emotional abuse/neglect history increases risk

Treatment of …

  • Cognitive-behavioral therapy

    • Exposure and response prevention (reducing mirror checking, avoidance)

    • Challenging distorted beliefs about appearance

  • Medication

    • SSRIs (higher dose than OCD)

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Compulsive behaviors

  • Mirror-checking, excessive grooming, reassurance seeking

  • Avoidance of social situations due to distress

  • Severe causes:

    • Social isolation

    • Depression

    • Suicidal ideation

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Obsessive-compulsive disorder (OCD)

Presence of obsessions (persistent, distressing intrusive thoughts), compulsions (repetitive behaviors or mental acts aimed at reducing distress), or both

Causes of …

  • Neurobiological factors

    • Dysfunction in orbitofrontal cortex, anterior cingulate cortex, and caudate nucleus

    • Low serotonin levels

  • Cognitive-behavioral factors

    • Attempts to suppress obsessions paradoxically increase their frequency

  • Evolutionary perspective

    • Compulsions like checking and washing may be exaggerated survival behaviors

Treatment of …

  • Medications

    • SSRIs (e.g., fluoxetine, fluvoxamine, sertraline) are the first-line treatment

    • Antipsychotics may be added for severe cases

  • Behavioral & cognitive-behavioral treatments

    • Exposure and response prevention (ERP)

      • Repeated exposure to feared stimuli without performing compulsions

      • Anxiety naturally reduces over time (habituation)

      • 50-70% symptom reduction, long-lasting effects

    • Cognitive therapy

      • Targets catastrophic beliefs about obsessions

      • May enhance ERP effectiveness

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Thought-action fusion

  • Belief that having a thought is morally equivalent to acting on it or increases the likelihood of it happening

    • Example: A mother with intrusive thoughts about harming her infant believes thinking it makes it more likely to happen

    • Results in:

      • Inflated sense of responsibility

      • Increased compulsive behaviors to prevent harm

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OCD

Diagnostic criteria for ____:

  • Obsessions and, if present, compulsions cause significant distress or impairment

  • Time-consuming (more than 1 hour per day)

  • Not attributable to substance use or another mental disorder.

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Hoarding disorder

Persistent difficulty discarding possessions, regardless of value

Results in …

  • Extreme clutter

  • Fire hazard

  • Unsanitary conditions

Neurobiological distinctions …

  • Different brain activation patterns than OCD

  • Poorer response to standard OCD treatments

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Trichotillomania

Recurrent pulling at hair resulting in hair loss

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Mood disorders

Involve extreme alterations in emotion—ranging from deep depression to intense, unrealistic euphoria

[Normal mood states may occur between episodes, although sometimes mixed symptoms can be present within a single episode]

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Unipolar depressive disorders

Only depressive episodes are experienced  

  • Lifetime prevalence 17%

  • 12-month prevalence 7%

  • Women twice as likely as men to experience major depression

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Bipolar disorders

Both depressive and manic (or hypomanic) episodes occur; normal mood states may occur between episodes, although sometimes mixed symptoms can be present within a single episode

  • Lifetime prevalence 1%

  • No specific gender differences

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Depressive episode

Markedly depressed mood or loss of interest in once pleasurable activities for at least 2 weeks

Additional symptoms:

  • Changes in sleep and appetite  

  • Feelings of worthlessness or guilt  

  • Difficulty concentrating  

  • Recurrent thoughts of death or suicidal ideation

Most common form of mood disorder

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Manic episode

Abnormally and persistently elevated, euphoric, or expansive mood lasting at least 1 week (or any duration if hospitalization is needed)

  • Accompanied by three (or four if mood is only irritable) additional symptoms such as: 

    • Inflated self-esteem or grandiosity  

    • Decreased need for sleep  

    • More talkative or pressured speech  

    • Flight of ideas or racing thoughts  

    • Distractibility  

    • Increase in goal-directed activity or psychomotor agitation  

    • Excessive involvement in high-risk activities

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Hypomanic episode

Similar symptoms to mania, but less severe, lasting at least 4 days, with no marked impairment or need for hospitalization

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Major depressive disorder (MDD)

Presence of a major depressive episode without any history of mania or hypomanic episodes

  • Key symptoms (at least 5 during a 2-week period) → symptoms must represent a change from previous functioning & cause significant distress or impairment:

    • Depressed mood most of the day  

    • Markedly diminished interest or pleasure  

    • Significant weight change or appetite disturbance  

    • Sleep disturbances (insomnia or hypersomnia)  

    • Psychomotor agitation or retardation  

    • Fatigue or loss of energy  

    • Feelings of worthlessness or excessive guilt  

    • Diminished ability to think or concentrate  

    • Recurrent thoughts of death or suicidal ideation

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Melancholic, psychotic

  • Specifiers for MDD:

    • _____ features: early morning awakening, depression worse in the morning, psychomotor changes, loss of appetite/weight, excessive guilt

    • ______ features: presence of delusions or hallucinations (usually mood-congruent

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Delusions

Faulty fixed beliefs that contradict reality and have no truth

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Hallucinations

Alterations in sensory perceptions without any external stimuli

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Atypical features (of MDD)

Mood reactivity (mood brightens in response to positive events) plus two or more symptoms (e.g., weight gain, hypersomnia, leaden paralysis, sensitivity to rejection)

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Catatonic features (of MDD)

Motoric immobility, including mutism and rigidity

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Seasonal pattern (of MDD)

Recurrent depressive episodes occurring at the same time each year with full remission in other seasons

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Persistent depressive disorder (PDD)

Depressed mood most of the day, on most days, for at least 2 years (1 year for children/adolescents) 

  • Additional symptoms (at least two of the following) 

    • Poor appetite/overeating

    • Insomnia/hypersomnia

    • Low energy

    • Low self-esteem

    • Poor concentration

    • Feelings of hopelessness

  • Key characteristic: intermittent periods of normal mood (lasting a few days to a few weeks, but never more than 2 months)

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Double depression

Co-occurrence of persistent depressive disorder and intermittent major depressive episodes

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Premenstrual dysphoric disorder

Symptoms appear in the final week before menses and improve soon after onset; key symptoms include affective lability, irritability/anger, depressed mood, or marked anxiety

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Post-partum blues

Common in new mothers (and occasionally fathers), with symptoms like mood lability, crying, sadness, and irritability occurring in up to 50-70% within 10 days of childbirth and typically subsiding on their own

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Hypoothalamic-pituitary-adrenal axis

Regulates cortisol release in response to stress

  • Elevated cortisol is observed in 20-40% of outpatients and 60-80% of hospitalized patients with depression 

  • In about 45% of patients with serious depression, dexamethasone fails to suppress cortisol levels (the “dexamethasone nonsuppressor” phenomenon)

  • Prolonged cortisol elevations can lead to memory impairments, cognitive difficulties, and cell death in the hippocampus

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Circadian rhythms

Regulate sleep & appetite

  • Abnormalities in these rhythms are commonly observed in depression

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Seasonal affective disorder (SAD)

Linked to the total quantity of available light; most patients become depressed in the fall/winter and normalize in spring/summer

  • Light therapy may help reestablish normal biological rhythms in affected individuals

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Sleep disturbances

______ _____ in depression

  • Normal sleep involves five stages (Stages 1-4 of non-REM and REM sleep)

  • Depressed patients frequently experience:  

    • Difficulty falling asleep and maintaining sleep   

    • Early morning awakening  

    • A shortened latency to the first REM period (often 15-20 minutes sooner than normal)  

    • Increased amounts of REM sleep in early cycles and reduced deep sleep

  • Such sleep changes are particularly pronounced in patients with melancholic features

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Severe stressful events

E.g., loss of a loved one, major economic or health crises often precipitate a major depressive episode

  • Distinction between independent life events (e.g., natural disasters) and dependent life events (those partly generated by the person’s behavior). 

  • Research indicates dependent life events may play a stronger role in triggering depression

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Chronic stress

Ongoing for several months (e.g., poverty, marital discord), is associated with increased risk for the onset, maintenance, and recurrence of depression

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Cognitive, biological

Psychological factors:

  • Stressful life events, personality traits (e.g., neuroticism), and negative cognitive styles all contribute to depression

  • _______ vulnerabilities (such as dysfunctional beliefs) may be activated by stressful events, triggering depressive symptoms

  • These psychological factors may also be mediated by underlying ______ changes (e.g., hormonal imbalances)

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Freud and Abraham

Psychodynamic theory

  • “Mourning and Melancholia” (1917) noted similarities between depression and the symptoms of mourning

  • Proposed that depression involves the regression to an earlier developmental stage and the introjection of the lost object, leading to anger turned inward

  • Emphasis on both real losses and symbolic losses (e.g., failure in school or relationships) as triggers for depression

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Aaron Beck

Cognitive theory

Argued that negative automatic thoughts often precede mood symptoms

  • Central to his model are dysfunctional beliefs or depressogenic schemas

    • The model highlights the “negative cognitive triad”: 

      • Negative views about the self (“I’m worthless”) 

      • Negative views about the world (“No one loves me”) 

      • Negative views about the future (“It’s hopeless because things will always be this way”) 

    • Cognitive biases (e.g., all-or-none thinking, selective abstraction, arbitrary inference) serve to maintain these negative thoughts

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Learned helplessness model

Cognitive theory

Originated from animal studies showing that uncontrollable shocks lead to passivity and depressive symptoms

  • In humans, exposure to uncontrollable negative events may lead to a sense of helplessness that parallels these findings

  • The reformulated helplessness theory emphasizes that the attributions people make about negative events (internal, stable, global) determine their vulnerability to depression

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Relationships, social

Interpersonal effects

  • Lack of close, supportive _____ increases vulnerability to depression

  • _____ isolation and deficits in interpersonal skills are risk factors

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Criticism

Interpersonal effects

Studies show that ______ (e.g., maternal criticism) elicits different neural responses in recovered depressed individuals

  • Less activation in the prefrontal cortex

  • Heightened amygdala response

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Parental, marital

Interpersonal effects

  • _____ depression raises risk for children

  • _____ distress can precipitate relapse in depression

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Interpersonal cascade

Depressive behaviors can evoke negative reactions from others (e.g., rejection, hostility)

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Persisting reassurance seeking

Effect of depression on others that may lead to strained relationships and further isolation

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Marital and family contexts

Unsupportive or critical environments contribute to worse outcomes and relapse

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Bipolar spectrum

Includes bipolar I, bipolar II, & cyclothymic Disorder

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Bipolar I disorder

Characterized by full-blown manic episodes (often with depression)

  • Presence of full-blown mania; depressive episodes may be present even if subthreshold

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Bipolar II disorder

Involves hypomanic episodes (less severe) and major depressive episodes

  • Presence of hypomania (milder, no hospitalization required) plus major depressive episodes

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Cyclothymic disorder

Chronic, fluctuating mood disturbances (hypomanic and depressive symptoms over ≥2 years)

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High heritability, family risk, shared genetics, polygenic

Genetic Factors in Bipolar Disorders

  • ____ __________: twin studies show ~60% concordance for monozygotic twins vs. ~12% for dizygotic twins

  • _____ ______: first-degree relatives have a markedly increased risk

  • _____ ______: some genetic polymorphisms overlap with schizophrenia and unipolar depression

  • _____ nature: multiple genes contribute to liability for bipolar disorder

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Monoamine hypotheses

Neurochemical & hormonal influences in bipolar disorders

  • Imbalances in norepinephrine, serotonin, and dopamine

  • Increased norepinephrine activity during mania; low serotonin in both phases

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Hormonal dysregulation

Neurochemical & hormonal influences in bipolar disorders

  • HPA axis abnormalities (e.g., elevated cortisol in depression)

  • Thyroid function: abnormalities can affect mood; thyroid hormone may enhance antidepressant efficacy but also precipitate mania

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Lithium therapy

  • Widely used for both depressive and manic episodes

  • Effective in reducing recurrence (especially in bipolar disorder)

  • Considerations:

    • Side effects - lethargy, weight gain, cognitive slowing, possible kidney issues

    • Alternative anticonvulsants (e.g., carbamazepine, divalproex) are used when lithium is not tolerated

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Women, men, low, increases

Epidemiology of Suicide 

  • Global impact:

    • Suicide is the 15th leading cause of death worldwide (≈1.4% of deaths)

  • Gender differences:

    • _____ are more likely to attempt suicide

    • _____ are about four times more likely to die by suicide due to use of more lethal methods

  • Age trends:

    • ____ in childhood

    • ____ from adolescence through young adulthood, with a middle-age peak

  • Pharmacological interventions:

    • Antidepressants may reduce suicidal ideation in adults, although concerns remain

    • Lithium shows strong anti-suicide effects in long-term management

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Key warning signs

Nearly 90-95% of suicide victims have a history of at least one psychiatric disorder

Risk increases dramatically with comorbidity

  • _____ ______ (immediate action needed):

    • Threats to self-harm or suicidal statements

    • Seeking access to lethal means (pills, weapons)

    • Talking or writing about death or suicide

    • Additional concerns → hopelessness, agitation, withdrawal, increased substance use, and dramatic mood changes

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Somatoform

  • Excessive thoughts, feelings, & behaviors about a bodily sensation

  • Disproportionate & persistent thoughts about the seriousness of symptom(s)

  • Excessive time & energy devoted to symptom(s)

  • Most tentative spectrum

  • Emotional dysfunction superspectrum

  • Difficult to derive due to less existing evidence

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Somatoform

  • Assessment symptoms of … : MMPI or MSPQ

    • There seems to be a fullness in my head

    • I have numbness in my skin

    • I have a lump in my throat often

    • I do not notice my ears ringing (reversed)

    • Desire to pass water

    • Mouth becoming dry

    • Butterflies in stomach

    • Muscles twitching or jumping

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Pain

Physical suffering

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Somatoform with pain

  • Disproportionate & persistent thoughts about the seriousness of pain symptoms

  • Disproportionately excessive time & energy devoted to pain symptoms

  • Ex. Patient w/ fibromyalgia whose symptoms aren’t responding to/managed by typical intervention

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Somatic symptom disorder

  • One or more x symptoms that are distressing or result in significant disruption of daily life 

  • Excessive thoughts, feelings, or behaviors related to the x symptoms or associated health concerns as manifested by at least one of the following:

    • Disproportionate & persistent thoughts about the seriousness of one’s symptoms

    • Persistently high level of anxiety about health or symptoms

    • Excessive time & energy devoted to these symptoms or health concerns

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Illness anxiety disorder

  • Preoccupation with having or acquiring a serious illness

  • Somatic symptoms are not present or, if present, only mild in intensity - if another medical condition is present or there is a high risk for developing a medical condition, the preoccupation excessive or disproportionate

  • High level of anxiety about health, & individual easily alarmed about personal health status

  • Individual performs excessive health-related behaviors or exhibits maladaptive avoidance

  • Illness preoccupation present for at least 6 months, but specific illness that is feared may change over that period of time

  • Illness-related preoccupation not better explained by another mental disorder

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Care-seeking type

Medical care, including physician visits or undergoing tests and procedures is frequently used

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Care-avoidant type

Medical care is rarely used

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Functional neurological symptom disorder (conversion disorder)

A type of somatic disorder that is sometimes applied to patients who present neurological symptoms, such as numbness, blindness, paralysis, or fits, which are not consistent with a well-established organic cause, cause significant distress, and can be traced back to a psychological trigger

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Functional neurological symptom disorder

______ ________ _______ ________ begins with some stressor, trauma, or psychological distress

  • Common symptoms include:

    • Blindness

    • Partial or total paralysis

    • Inability to speak

    • Deafness

    • Numbness

    • Difficulty swallowing

    • Incontinence

    • Balance problems

    • Seizures

    • Tremors

    • Difficulty walking

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Factitious disorder

A condition in which a person, without a malingering motive, acts as if they have an illness by deliberately producing, feigning, or exaggerating symptoms, purely to attain (for themselves or for another) a patient's role; people with a factitious disorder may produce symptoms by contaminating urine samples, taking hallucinogens, injecting fecal material to produce sickness, and similar behavior

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Factitious disorder imposed on another (also called Munchausen syndrome by proxy)

A condition in which a person deliberately produces, feigns, or exaggerates the symptoms of someone in their care

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Dissociative

Characteristics of _______ disorders

  • Individuals becoming split off, or dissociated, from their core sense of self

  • Memory & identity become disturbed; disturbances have a psychological rather than physical cause

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Depersonalization

Characteristic of dissociative disorders:

A feeling of detachment or estrangement from one’s self; feeling as if you are an onlooker of your own body

  • Qualitative study, conducted by by Ciaunica et al., 2023, reveals lived experienced of individuals struggling with depersonalization, and found three core themes: 

  • Individuals with high levels of depersonalization reported:

    • Detachment from the world and one’s self – “I just feel like I’m watching myself over a distance and I don’t know who I am”

    • Embodiment, denoting unusual or changing experiences of the body – “whenever I feel intimidated, I tend to lose control of my body and can’t move properly”

    • Identity changes, a lack of congruence between one’s felt self and one’s words and action — “My thinking self and my speaking self feel different”

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Derealization

Characteristic of dissociative disorders:

An alteration in the perception of one’s surroundings so that a sense of reality of the external world is lost; the world you are experiencing doesn’t feel real

  • The sense that one is in a “fog”

  • A see-through wall or veil is separating you from your surroundings

  • The world appears lifeless, muted, or fake

  • Objects or people look “wrong” – blurry,  unnaturally sharp, too big, or too small

  • Sounds are distorted, too loud, or too soft

  • Time seems to speed up or stand still

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Dissociative amnesia

Characteristic of dissociative disorders:

When dissociation causes memory loss

  • How memory works:

    • Encoding: the receival and interpretation of information

      • The act of getting info into our memory from either automatic and effortful processing

    • Storage: maintaining information over time

      • The retention of encoded information

    • Retrieval: the ability to access information when you need it

      • The act of getting information out of storage and into awareness through recall and recognition

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Retrograde

When dissociative amnesia affects finding old memories

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Anterograde

When dissociative amnesia blocks the formation or storage of new memories

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Identity confusion

Characteristic of dissociative disorders:

Thoughts & feelings of uncertainty & conflict a person has related to their identity

  • “I have a feeling that I am made up of two or more people”

  • “It happens that I have the feeling that my mind is split up”

  • “At times it seems as if someone else inside of me decides what I do”

  • “It happens that I have the feeling that I am somebody else”

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Identity alteration

Characteristic of dissociative disorders:

Manifestations of alters (or alternative identities) containing & expressing different opinions, perceptions, & senses of self

  • Individuals may notice a shift in their sense of how old they are, their gender identity, their preferences, skills, and memories 

  • Even vocal pitch, body language, and physical reactivity to stress can change

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Anorexia nervosa

  • Not simply a “lack of appetite” but a relentless pursuit of thinness leading to a significantly low body weight

  • DSM-5 criteria:

    • A - restriction of energy intake resulting in significantly low body weight

    • B - intense fear of gaining weight or becoming fat

    • C - disturbance in body weight/shape perception

  • Subtypes:

    • Restricting type - extreme limitations of food intake

    • Binge-eating/purging type - binging/purging behaviors

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Bulimia nervosa

  • Characterized by recurrent binge eating followed by inappropriate compensatory behaviors

  • DSM-5 criteria highlights:

    • Recurrent episodes of binge eating (eating an unusually large amount of food in a short time with a loss of control)

    • Inappropriate compensatory behaviors (self-induced vomiting, misuse of laxatives, fasting, or excessive exercise)

    • Occurs at least once a week over 3 months

  • Clinical notes:

    • Typically, individuals are within a normal weight range or slightly overweight

    • Often accompanied by feelings of shame and guilt

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Anorexia nervosa

  • Weight: Markedly low

    • Atypical anorexia: extreme weight loss, but bmi remains in the “normal” range (could be due to starting at a higher weight)

  • Behavior: Restrictive intake (or binge/purge in one subtype)

  • Body Image: Distorted perception; intense fear of weight gain

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Bulimia nervosa

  • Weight: Normal or slightly overweight; no pronounced weight loss

  • Behavior: Binge eating with compensatory behaviors

  • Body Image: Overconcern with weight; feelings of shame

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Binge-eating disorder

  • Weight: Often overweight or obese; not a requirement

  • Behavior: Binge eating without compensatory measures

  • Body Image: Concerns present, though less rigid dietary restraint compared to other disorders

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Risk factors and demographics

  • Age of onset

    • Most eating disorders begin in adolescence

    • Binge-eating disorder often develops between ages 30-50

  • Gender differences

    • Historically seen as predominantly affecting females; current ratio is about 3:1 (female:male)

    • Men’s body dissatisfaction may focus on muscularity

  • High-risk groups

    • Individuals in professions emphasizing thinness (e.g., models, ballet dancers)

    • Athletes in sports with weight restrictions

    • Sociocultural pressures and media influence play significant roles

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Anorexia nervosa

Medical complications:

  • Heart arrhythmias and risk of cardiac arrest

  • Electrolyte imbalances leading to kidney damage

  • Osteoporosis due to low bone density

  • Other signs: dry skin, brittle hair, lanugo (fine hair growth)

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Bulimia nervosa

Medical complications:

  • Dental erosion and mouth ulcers from repeated vomiting

  • Swollen salivary glands

  • Electrolyte disturbances impacting heart and muscle function

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Biological

________ factors 

  • Genetic predisposition

    • Family and twin studies indicate high heritability for anorexia and bulimia nervosa

    • Recent GWAS found a genetic locus on chromosome 12 linked to anorexia nervosa and metabolic factors

  • Brain structure & neurotransmitter imbalances

    • Hypothalamus role - lateral hypothalamus stimulation promotes appetite

    • Serotonin - abnormalities (such as altered 5-HIAA levels) suggest disrupted serotonergic function

  • Set points & reward sensitivity

    • The body’s “set point” resists significant weight changes

    • Differences in reward processing (e.g., response to food cues) may predispose to binge eating or restrictive behaviors

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Sociocultural

________ influences 

  • Media & cultural ideals

    • Exposure to Western media (TV, magazines) is linked to body dissatisfaction

    • Studies (e.g., in Fiji) show that media can shift local attitudes toward thinness

    • Icons like Twiggy and Kate Moss have influenced the “thin ideal”

  • Internalization of the thin ideal

    • Believing that thinness equals beauty and success increases risk

    • Social comparisons and peer evaluation reinforce these beliefs

  • Family influences

    • Families of patients often exhibit rigid attitudes, high expectations, and focus on dieting

    • Parental preoccupation with appearance may contribute to the development of eating disorders

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Individual, perfectionism

_______ variables 

  • Personality traits 

    • ________: an enduring trait linked to rigid dieting and excessive self-criticism; more pronounced in women; men with eating disorders tend to be less perfectionist

  • Body dissatisfaction

    • A powerful predictor of eating disorder onset

    • Distorted self-perceptions lead to chronic dieting and negative self-evaluation

  • Negative emotionality & dieting behaviors

    • Dieting is common and can trigger or worsen disordered eating

    • Negative moods and depression are predictive of binge eating and dietary restriction

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