6.4 viroids, virusoids, and prions

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Last updated 5:37 PM on 3/4/26
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10 Terms

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viroids

- virus-like but not a virus

- circular RNA that can self-replicate (no DNA conversion)

• No protein coating

(capsid)

• Important to agriculture

ex. potato tuber spindle disease

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virusoids

• Subviral particles

• Non-self replicating ssRNAs

• Part of satellite virus group & require a "helper" virus

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virusoid example

subterranean clover mottle virus

• Virus contains virusoid in capsid

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What are prions?

Misfolded rogue proteins that can cause others to become misfolded.

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Do all infectious agents have genomic material?

No, not all infectious agents have genomic material.

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What diseases are caused by prions?

Transmissible spongiform encephalopathy, such as mad cow disease and CJD.

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How are prions transmitted between animals and to humans?

Through eating contaminated meat/feed.

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How can prions be transmitted from human to human?

Through heredity.

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What is a key characteristic of prions regarding destruction?

They are difficult to destroy.

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Is there a treatment for prion diseases?

No, there is no treatment.

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