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What is Science?
seeks to answer questions about the natural world
Scientific Method
Observations, Question, Hypothesis, Prediction, Test
What are some characteristics of living stimuli?
order, response to stimuli, growth, reproduction, inheritance of genetic information, regulation, homeostasis, acquire and use energy, and evolution.
Biotic Factors
fungi, bacteria, plants, artists, animals, and archea
Abiotic Factors
air, salinity, soil, temperature, light, water, minerals, pH, humidity
What is the cell theory?
cells are the basic building blocks of life; all living things or organisms are made of cells and their products; new cells arise from existing cells.
Parthenogenesis
new individual develops without fertilization
What is basic science?
answers questions about the natural world
What is applied science?
uses information gained to: create a product, treat a disease or condition, improve life, or fulfill some other practical need.
Viruses
have DNA or RNA and proteins but this genetic information and proteins vary.
How do viruses reproduce?
they bind to a host cell and its genome (DNA or RNA) enters, then the host cell copies viral genome and makes proteins, leading to a self-assembly into a new virus.
Prokaryotes
no nucleus
Eukaryotes
have a nucleus
What do all cells have?
a plasma membrane, cytoplasm, DNA, and ribosomes.
Domains
based on differences in the genetic structure of ribosomes.
What are the three domains?
Archea, Eucarya, and Bacteria
What domain are humans in?
Eucharya
Taxonomy
grouping of organisms by scientific means (features, DNA)
Levels of Organization in Biology
Cells
Organism
Populations
Communities
Ecosystems
Biosphere
Epidemic
an outbreak of disease that affects many in a population and begins to spread rapidly.
Pandemic
covers several countries or spreads from one continent to another; amount of people killed doesn’t matter as much as the rate of spread and how far it has spread.
Epidemiologists
study the spread of disease in human populations.
Communicable Disease
can get it from someone else.
Noncommunicable disease
is not spread from person to person
What was the first commercialized antibiotic and who discovered it?
Penicillin; Alexander Fleming
Antibiotics
chemicals produced naturally by microorganisms or synthetically, by humans that prohibits the growth of other microbes.
What is the main target of antibiotics?
to get the ribosome to stop protein production in bacterial cells; kill bacteria and fungi but not viruses.
Antimicrobial Resistance
viruses can become resistant to antiviral medications (Flu A, HIV)
Human Microbiome Project
identified microbial communities across the body
What does the human microbiome do?
processes food, processes waste, and improves the immune system.
Vagus (wandering) Nerve
communication pathway from your gut to your brain
Benefits of Breastfeeding
protects against childhood infections, reduces dental problems, improves survival rates, reduced risk for asthma, type 2 diabetes, and other disease
What percentage of a baby’s microbiome is from the milk and what percentage is from the mothers skin?
Milk: 30% Skin: 10%
What are some of the barriers of the human body that prevent infection?
skin when undamaged, physical and chemical barriers, acidic secretions of stomach, cilia, mucus, enzymes in tears and saliva, and the microbiome
Innate immune response
non-specific responses do not recognize invaders from previous attacks.
Macrophages
engulf and digest invading particles or organisms
Leukocytes
white blood cells
T-Cells
kill infected cells
B-Cells
produce antibodies against the pathogen so cells will not be infected; some B cells become memory cells (adaptive response)
Lymphatic System
antigens from lymph filtered through lymph nodes; antigens and antibody-complexed pathogens from blood filtered through the spleen (which is also lymph tissue)
Lymphoid Tissue
integrated into tissues of skin and intestines, bone marrow
How are vaccinations developed?
by using a dead organism, a mildly infectious pathogen, toxins from pathogen which have been inactivated, or through mRNA
How do vaccines work?
they stimulate an adaptive immune response
Autoimmune disease
a body amounts an immune response against its own tissues.
Plasma Membrane
surrounds each cell; regulates what goes in and out depending on cell type and role.
What do receptor molecules on the plasma membrane do?
they recognize a signal from outside the cell, transport that signal across the cell’s membrane and initiate the reading and response to that signal.
Evolution
a change in allele frequency in a population over time.
Allele
variation in a gene, such as blood type A or B
Natural Selection
a mechanism for evolution; preserves favorable variations.
What is the role of the nucleus?
it holds our DNA
Phenotype
physical expression of a trait: how you look, act, respond to stimuli (internal or external)
Adaptation
inherited trait (phenotype) that enhances survival in a particular enviornment.
What causes genetic variation in populations?
mutations in the DNA; change in one DNA base in a genotype can lead to a new phenotype; sexual reproduction can produce new combinations.