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lithium - MOA
not known
lithium - indications
management of acute manic or hypomanic episode
prevention of further manic and depressive episodes
what is lithium often combined with?
benzos or antipsychotics
lithium- AE
GI (N/V/D), weight gain, polydipsia, polyuria, mental dullness, decreased memory concentration, fine hand tremor, fatigue, muscle weakness, osteoporosis
what does lithium require?
frequent plasma concentration monitoring
lithium toxicity
serum concentrations, occurs close to therapuetic levels
illness, diets, exercise, hot climate, surgery, advanced age, pregnancy can alter concentrations
what should you educate patients on about lithium?
adequate hydration & consistent Na intake
DDI- monitor drug regimen changes
anticonvulsant meds - indications
for acute manic episodes, mixed episodes, and maintenance
anti seizure drugs
anticonvulsant names
valporic acid
carbamazepine
lamotrigine
anticonvulsant - AE
dermatologic reactions
immediately refer for rashes (benign vs serious)