Studied by 2 peoplePatrilineage
The Y chromosome is inherited from the father and is passed on to all male offspring.
Pseudoautosomal Regions (PARs)
Homologous nucleotide sequences that are present on the X and Y chromosomes.
PAR1
It is located on the terminal region of the short arm. It comprises 2.6 Mb. Twenty-four genes have been identified within the PAR1.
PAR2
It is located at the tip of the long arm. It comprises 320 kb, with only four genes identified so far.
Male-Specific Y Region
The remainder of the Y chromosome.
DYF155S1
The first characterized VNTR at the human Y chromosome. It consists of an array of AT-rich repeats at 25 bp per unit repeat.
X-chromosomal STR (X-STR) profiling
is a useful tool in kinship testing in forensic investigations.
homologous PARs
Homologous recombination between the X and Y chromosomes is restricted to the _______.
paternal X chromosome
The _________ is inherited by daughters as haplotypes.
Recombination Fraction
The percentage of recombinants resulting from chromosomal crossover between two loci during meiosis among all the offspring.
Amelogenesis Imperfecta
A disorder that causes abnormal formation of tooth enamel in both primary and permanent teeth.
AMEL X
AMEL locus which is located on the human X chromosome.
AMEL Y
AMEL locus which is located on the human Y chromosome.
Sex-determining region Y (SRY) gene
Encodes a transcription factor that plays a role in the regulation of sex determination toward male development.
HMG box
The SRY protein contains a DNA-binding domain known as the _____.
SOX3
An SRY-related HMG box-containing gene, has been identified at Xq27.1 of the X chromosome, which shares sequence homology with SRY.
TSPY Locus
It encodes the testis-specific protein Y-encoded gene that is only expressed in the testis and may play a role in spermatogenesis.
DYS14
A marker utilized for the characterization of the TSPY locus.
TSPY-like (TSPYL) gene
It has been identified on the short arm of the X chromosome and is designated as TSPYL2.
TSPYL2
A single-copy gene per X chromosome and is 6.3 kb in length, consisting of 7 exons and 6 introns.
DXYS156
A polymorphic pentanucleotide STR. It is located at the pseudoautosomal region of both X and Y chromosomes, is another candidate marker used for sex typing.
DXYS156 Y
Alleles that have an additional adenine insertion in the repeat units of STR.
Steroid sulfatase (STS) gene
Encodes an enzyme that catalyzes the conversion of sulfated steroid precursors to biologically active steroids such as estrogens and androgens.
Note 
Flashcard (86)