_____ is the study of all living things that are too small to be seen with the naked eye.
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Pathogen
_____ is a disease-causing organism.
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Non-pathogen
Are those that do not damage, sicken, or kill another organism are called ____
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Opportunistic Pathogen
_____ are frequently described as organisms in the medical literature that can become pathogenic after an alteration to their host (e.g., disease, wound, medication, prior infection and immune-deficiency).
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2 MAJOR CATEGORIES OF
MICROBES
ACELLULAR MICROBES & CELLULAR MICROBES
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ACELLULAR MICROBES
aka infectious particles Prions Viruses.
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CELLULAR MICROBES
microorganisms, prokaryotes such as archaea and bacteria, eukaryotes such as algae, fungi and protozoa
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WHY STUDY MICROBIOLOGY?
indigenous flora= inside the body or host
\ opportunistic pathogens= may invade the system if the host body is weak or have diseases, wound or injuries.
\ microbes are essential for life on this planet= they regenerate important elements such as oxygen and nitrogen.
\ decomposition of dead organisms and the waste=organic molecules to inorganic molecules. products of living organisms
\ bioremediation= the decomposition of industrial waste ex. plastics
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WHY STUDY MICROBIOLOGY?
microbial ecology= elemental cycle. Nitrogen fixation is the way of converting nitrogen into usable form “nitrates”. Also, electrical energy which is a natural way—raining and precipitation.
\ algae and cyanobacteria serve as food for tiny animals= producers. Algae produce oxygen essential for life.
\ Biotechnology= infectious disease control. Research and experimentation on microorganisms.
is when a pathogen produces a toxin in vitro that causes a disease.
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INFECTIOUS DISEASE
_____ is when a pathogen colonizes a person's body causing disease or illness.
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(3) LEADING PIONEERS IN THE SCIENCE OF MICROBIOLOGY
Anton Van Leewenhoek
Louis Pasteur
Robert Koch
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ANTON VAN LEEWENHOEK
Father of Microbiology Father of Bacteriology Father of Protozoology
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ANTON VAN LEEWENHOEK
he made one of the most significant contributions to biology by becoming one of the first individuals to see microbes using a microscope of his own design.
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ANTON VAN LEEWENHOEK
discovered living organisms that he called "animalcules."
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LOUIS PASTEUR
he discovered what occurs during alcoholic fermentation
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LOUIS PASTEUR
He created the pasteurization method, where boiling beverages and letting them cool eliminates microorganisms.
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LOUIS PASTEUR
he discovered the forms of life that could exist in the absence of oxygen; he introduced "aerobes" and "anaerobes
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LOUIS PASTEUR
he made significant contributions to the germ theory of disease - theory that states specific microbes cause specific infectious diseases
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LOUIS PASTEUR
he developed vaccines to prevent chicken cholera, rabies anthrax, and swine erysipelas
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ROBERT KOCH
created the Germ Theory of Disease and Koch’s postulates
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ROBERT KOCH
he discovered that Bacillus anthracis produces spores
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ROBERT KOCH
he developed methods of fixing, staining, and photographing bacteria
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ROBERT KOCH
he discovered Mycobacterium tuberculosis causes TB and Vibrio cholerae causes cholera
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ROBERT KOCH
he developed methods of cultivating bacteria on solid media (Petri dish and agar) - these methods enabled Koch to obtain PURE CULTURES of bacteria
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Koch’s Postulates
four standards used to prove a link between a sickness and the causative microbes.
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Discuss the (4) postulates of Koch
1. The microorganism must be found in abundance in all organisms suffering from the disease, but should not be found in healthy organisms. 2. The microorganism must be isolated from a diseased organism and grown in pure culture. 3. The cultured microorganism should cause disease when introduced into a healthy organism. 4. The microorganism must be reisolated from the inoculated, diseased experimental host and identified as being identical to the original specific causative agent.
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Exception of Koch’s Postulate
1. certain pathogens will not grow on artificial media 2. synergistic infections 3. many pathogens are species-specific, meaning that they infect only one species of animal 4. certain pathogens become altered when grown in vitro; some become less pathogenic, whereas other become nonpathogenic