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when does positive charge run down the inside of the axon?
when the axon is wide
when does positive charge go across the axonal membrane?
when the axon is narrow
the larger the axonal diameter…
the increase in action potential conductance velocity
what affects axonal excitability?
axonal size and the number of voltage gated channels
what do smaller axons require?
greater depolarization to reach threshold
saltatory conduction
myelin sheath insulates the electrical signals and allows action potential to spread further and quicker
what do schwann and oligodendroglial cells do to the Na+ channels in myelin sheath?
make them concentrated in the nodes of ranvier
what parts of the neuron do not generate sodium dependent action potentials?
dendrites and the neuronal cell body
what is considered the spike initiation zone in neurons?
axon hillock
spike initiation zone
area where action potentials can occur closest to the soma
what does the depolarization of dendrites/soma lead to generation of APs?
only if the axon hillock is depolarized beyond threshold
where does the spike zone occur?
near sensory nerve endings