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psychoactive drugs
a chemical substance that alters perceptions and moods; can lead to addiction and substance use disorder
When is drug use a disorder?
diminished control, diminished social functioning, hazardous use, drug action
alcohol + effects
depressant; initial high followed by relaxation and disinhibition; depression, memory loss, organ damage, impaired reactions
heroin + effects
depressant; Rush of euphoria, relief from pain; Depressed physiology, agonizing withdrawal
caffeine + effects
stimulant; increased alertness and wakefulness; anxiety, restlessness, and insomnia in high doses, uncomfortable withdrawal
nicotine + effects
stimulant; Arousal and relaxation, sense of well-being; Heart disease, cancer
Cocaine + effects
stimulant; Rush of euphoria, confidence, energy; Cardiovascular stress, suspiciousness, depressive crash
Methamphetamine (Meth) + effects
stimulant; euphoria, alertness, energy; irritability, insomnia, hypertension, seizures
Ecsatsy + effects (MDMA)
Stimulant, mild hallucinogen; Emotional elevation, disinhibition; Dehydration, overheating, depressed mood, impaired cognitive and immune functioning
LSD + Effects
Hallucinogen; visual "trip", Risk of panic
What type of drug is marijuana?
Mild hallucinogen
What are the positive effects of marijuana?
Enhanced sensation, relief of pain, distortion of time, relaxation
What are the negative effects of marijuana?
Impaired learning and memory, increased risk of psychological disorders
Hallucinogens
distort perceptions and evoke sensory images
What can hallucinogens cause?
false sensory hallucinations, impair memory, feelings of relaxation and/or euphoria
Depressants
drugs that reduce neural activity and slow body functions
What can depressants cause?
increase relaxation and pain relief, decrease mood arousal; slow down (depress) bodily processes
Stimulants
drugs that excite neural activity and speed up body functions
What can stimulants cause?
increase energy, decrease appitite, brief sense of euphoria; speed up (stimulate) bodily processes
alcohol use disorder
The prolonged and excessive drinking, can shrink the brain
addiction
compulsive drug craving and use, despite adverse consequences
tolerance
the diminishing effects with regular use of the same dose of a drug
withdrawal
the discomfort and distress that follow discontinuing an addictive drug or behavior
near-death experience
an altered state of consciousness reported after a close brush with death; often similar to drug-induced hallucinations
Psychoactive drugs work by
stimulating, inhibiting and mimicking neurotransmitter activity
agonists
drugs which mimic the activity of neurotransmitters
antagonist
blocks or impedes the normal activity of a neurotransmitter at the receptor
endocrine system
the body's "slow" chemical communication system; a set of glands that secrete hormones into the bloodstream
horomones
chemical substances that carry messages through the body in blood
pituitary gland
The endocrine gland at the base of the brain that controls growth and development
hypothalamus
brain region controlling the pituitary gland
thyroid gland
produces hormones that regulate metabolism, body heat, and bone growth
parathyroids
help regulate the level of calcium in the blood
adrenal glands
top of kidneys, glands that help the body recover from stress and respond to emergencies
Pancreas
below stomach, Regulates the level of sugar in the blood
Neurotransmitters
chemical messengers that cross the synaptic gaps between neurons
reuptake
process by which neurotransmitters are taken back into the synaptic vesicles
Acetylcholine (ACh)
enables muscle action, learning, and memory
An undersupply of Acetylcholine can lead to
Alzheimers
An oversupply of acetylcholine can lead to
Paralysis
Dopamine (DA)
regulates motor behavior, motivation, pleasure, and emotional arousal
An undersupply of dopamine can lead to
Parkisons
An oversupply of dopamine can lead to
Schizophrenia
Seritonin
Affects mood, hunger, sleep, and arousal
An undersupply of seritonin can lead to
depression
Norepinephrine (NE)
Mainly excitatory; involved in arousal and mood
GABA
inhibitory neurotransmitter
Glutamate
A major excitatory neurotransmitter; involved in memory
An undersupply of GABA can lead to
seizures, tremors, insomnia
An undersupply of Glutamate can lead to
concentration problems
An oversupply of Glutamate can lead to
sezuires or migranes
Endorphins
preception of pain and pleasure
An undersupply of endorphins can lead to
depression
An oversupply of endorphins can lead to
anxious/tired
Substance P
a neurotransmitter involved in pain perception
adrenaline
A hormone released into the bloodstream in response to physical or mental stress; "flight or fight"
What is oxytocin?
A hormone released by the pituitary gland.
What are the functions of oxytocin?
Causes increased contraction of the uterus during labor and stimulates the ejection of milk into the ducts of the breasts.
cortisol
maintains homostatsis, stress hormone
Soma/Cell Body
contains nucleus and DNA
Dendrites
receive messages from other neurons
Axon
the neuron extension that passes messages through its branches to other neurons
Myelin Sheath
covers the axon of some neurons and helps speed neural impulses
Axon Terminals/Terminal Buttons
transmit signals to the dendrites
Schwann cells
produce myelin in PNS
Glial Cells (glia)
cells in the nervous system that is the support system for the neurons
Resting potential of a neuron
A stable, negative charge when the cell is inactive; ions are polarized
Threshold
the level of stimulation required to trigger a neural impulse
Action potential of a neuron
a neural impulse; a brief electrical charge that travels down an axon; ions are depolarized
All-or-nothing Law/Response
a neuron's reaction of either firing (with a full-strength response) or not firing as long as threshold is met
Nodes of Ranvier
gaps in the myelin sheath
Refactory Period
a period of inactivity after a neuron has fired
neurotransmitters
chemical messengers that cross the synaptic gaps between neurons
reuptake
process by which neurotransmitters are taken back into the synaptic vesicles
nervous system
the network of nerve cells and fibers that transmits nerve impulses between parts of the body.
neurons
a nerve cell; the basic building block of the nervous system
Peripheral Nervous System (PNS)
anything that controls any part of your body; sensory and motor
Central Nervous System (CNS)
consists of the brain and spinal cord
Afferent Nerves
sensory nerves; nerves that carry information about the external environment to the brain and spinal cord
Efferent Nerves
motor nerves; nerves that carry information out of the brain and spinal cord to other areas of the body
autonomic nervous system (ANS)
a set of nerves that carries involuntary and automatic commands that control body organs and glands
Somatic Nervous System (SNS)
the part of the peripheral nervous system that controls voluntary movement of skeletal muscles
Sympathetic Nervous System (SNS)
The component of the autonomic nervous system that responds to stressful situations by initiating the fight-or-flight response
Parasympathetic Nervous System
a set of nerves that helps the body return to a normal resting state
Interneurons
Central nervous system neurons that internally communicate and intervene between the sensory inputs and motor outputs
Reflexes
simple, automatic responses to sensory stimuli
Entric Nervous System (ENS)
an independent neural system involved with digestion; capable of signaling the brain regarding stress and other emotions