D652 Pigmented Lesions I+II

What is the most common site for Physiologic Pigmentation?

Attached gingiva

What is the cause of Physiologic Pigmentation?

Increased melanocytic activity AND more melanocytes

What is the disease process of Physiologic Pigmentation?

Congenital

What is the disease process of an Oral Melanotic Macule?

Idiopathic

An Oral Melanotic Macule is caused by a focal ________ in _______ deposition

increase; melanin

What is the most frequent melanocytic intraoral lesion?

Oral Melanotic Macule

Most common site for an Oral Melanotic Macule?

Lower lip vermillion

T/F: Oral Melanotic Macules are solitary

True

Do Oral Melanotic Macules have malignant potential?

Noj

What type of biopsy do we do for an Oral Melanotic Macule? On which 2 sites do we especially want to biopsy?

Excisional biopsy; palate and gingiva

Do you need to biopsy an Oral Melanotic Macule on the lower lip?

No

What is the disease process of Smoker’s Melanosis?

Reactive/Traumatic

What area is most commonly affected in Smoker’s Melanosis?

Anterior facial gingiva

How do we treat Smoker’s Melanosis?

Cessation results in gradual disappearance of areas of pigmentation, but biopsy should be considered if it is in unexpected locations (ex. HARD PALATE) / is unusual

What is the disease process of an Amalgam Tattoo?

Reactive/Traumatic

Amalgam Tattoos appear as a ______ [macule/plaque/vesicle/bulla/papule/nodule]

Macule

How do we treat an Amalgam Tattoo if it does not appear radiographically?

Biopsy

What is the disease process of Actinic Lentigo?

Reactive/Traumatic

Actinic Lentigo is a hallmark of ____________ ____

photodamaged skin

Actinic Lentigo is a/n ______ [cutaneous/skin] lesion exclusively

cutaneous

Actinic Lentigo involves _________ pigmented lesions with ____-__________ borders

uniformly; well-demarcated

Does Actinic Lentigo have malignant potential?

No

What is the disease process of Melasma?

Reactive/Traumatic

Melasma is the hyperpigmentation of ___-_______ skin of the ____ and ____.

sun-exposed; face; neckMelasma

Melasma is associated with _________

Pregnancy

T/F: Melasma is unilateral

False; Melasma is bilateral

What is the disease process of Oral Melanocanthoma?

Reactive/Traumatic

Is Oral Melanocanthoma common?

NO - it is exceedingly rare

What is the most common site for Oral Melanocanthoma?

Buccal mucosa

Is Oral Melanocanthoma more likely to be solitary or bilateral or multifocal?

Solitary

How quickly does Oral Melanocanthoma increase in size?

Rapidly

Does Oral Melanocanthoma have malignant potential?

No

How do we treat an Oral Melanocanthoma?

Incisional biopsy

I ended at Acquired Melanocytic Nevus

Cool