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Cancer
A disease in which some of the body’s cells grow uncontrollably and spread to other parts of the body
Carcinoma
Cancer that begins in the skin or epithelial cells
Sarcoma
Cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective and supportive tissue
Leukemia
Cancer that starts in blood-forming tissue
Lymphoma and myeloma
Cancers that begin in the cells of the immune system
What is the most common cancer for men?
Prostate
What is the most common cancer for women?
Breast
What cancer has the highest death rate?
Lung and bronchus
What is the lifetime probability of developing cancer (prostate cancer) for males?
1 in 2 (1 in 8)
What is the lifetime probability of developing cancer (breast cancer) in females?
1 in 3 (1 in 8)
Is radiation therapy a localized or systemic therapy?
Localized
If a treatment is curative, what happens to the tumor?
Tumor is completely removed
If a treatment is palliative, what happens to the tumor?
Tumor size is reduced to reduce pain
Radiation therapy can be concurrent
Radiotherapy can be used with chemotherapy
Radiation therapy can be an adjuvant
Radiation therapy can used as an post operative treatment to decrease local reoccurrence
Why does radiation tend to damage more cancer cells than normal cells?
Cancer cells rapidly synthesize DNA
Pharmacodynamics
The study of the relationship between concentrations of a drug and its biological effects with time
Pharmacokinetics
The study of the absorption, distribution, metabolism, and excretion of drugs from the body
What is the dose required to produce a therapeutic effect?
ED50
What is the dose required to produce a toxic effect?
TD50
What is the therapeutic index/ window?
TD50/ED50
