psychosis

abnormal condition of the mind

psychosis

cause: increased ____ activity in the ____

dopamine, CNS

MOA for antipsychotic drugs (2)

block CNS dopamine receptors, dopamine antagonist

2 common types of antipsychotics

traditional vs atypical

traditional antipsychotics

• end in ____

• ____ gen drug

“zine”, “dol”, 1st

atypical antipsychotics

• ____ gen

• end in _____

• ____ side effects

2nd, apine, fewer

adverse effects of traditional agents

orthostatic hypotension, sedation, anticholinergic effects

adverse effects of atypical agents

weight gain, disturbed lipid/glucose metabolism

atypical drugs that have less adverse effect but can cause weight gain

clozapine, olazapine

primary concern will all antipsychotic drugs = ____ effects

extrapyramidal

extrapyramidal side effects

• ______: slow, improper movement

• ______

• _____: bouncing leg

• other _____

• sudden _____ - life-threatening

tardive dyskinesia, pseuoparkinsonism, akathisia, dyskinesias, arrythimia

rehab concerns

• benefits vs _____

• alert for _____

• recognize _____ side effects

sedation, orthostatic hypotension, extrapyramidal

other uses for antipsychotic meds (5)

bipolar, depression, autism, anxiety, dementia