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layers of pericardium
Superficial to deep
fibrous pericardium
serous pericardium
pericardial cavity (In between parietal and visceral layer in serous filled with pericardial fluid)
layers of heart wall
Superficial to deep
epicardium
myocardium
endocardium
epicardium function
protecting the heart
myocardium function
(cardiac muscle) pumping of the heart
muscle fibers are involuntary , striated, and branched
endocardium function
(squamous epithelium) lines the inside of myocardium and covers valves and large vessels
atria
2 upper chambers
interatrial septum
auricle: (dog ear) and allows blood to collect
fossa ovalis: remnant of opening fetus right to if blood was foramen ovale (by passes lungs)
ventricles
2 lower chambers
interventricular septum
atria is the thinnest (no pumping)
right ventricle a little bit thicker pumps to the lungs= pulmonary circulation
left ventricle is thickest muscle and pumps blood to the rest of the body
which chamber is the thinnest and why?
atria; no pumping
which chamber is medium sized and what does it do?
right ventricle; pumps to the lungs (pulmonary circulation)
which chamber is the thickest and why?
left ventricle; pumps to the rest of the body
valves function
function: allow blood to flow in one direction to prevent backflow
what are the 4 valves?
atrioventricular (AV) (2): between atria and ventricles
bicuspid (mitral) valves: left side of heart
tricuspid valves: right side of heart
semilunar valves (2): between ventricle and vessel/artery
pulmonary semilunar valves
aortic semilunar valves
AV valves
anchored in place by chordae tendineae (heart strings) and papillary muscles
Semi-lunar valves
closed during relaxation, opened during contraction
AV vales and semi-lunar valves work opposite of each other to force a one-way path of blood through the heart
lubb vs dubb
lubb: AV valves closing (ventricular systole begins)
dubb: semi-lunar valves closing (end of ventricular systole)
Systemic circulation
blood flows on left side of heart through body tissues and back to the right side of the heart (left vent to right atrium)
Pulmonary circulation
blood flows from the right side of the heart to the lungs and back to left side of the heart (right vent to left atrium)
Blood flow of heart order
SVC and IVC and coronary sinus dump blood into the right atrium from right atrium through the tricuspid valve, blood travels to right ventricle
from the right vent, blood leaves the heart as it passes through the pulmonary semi-lunar valve into the pulmonary trunk
pulmonary trunk splits into right and left pulmonary arteries that carry blood to the lungs
oxygen is picked up and CO2 is dropped off by blood capillaries in the lungs
oxygen-rich blood returns to the heart through the four pulmonary veins
blood eneters the left atrium and travels through the bicuspid valve into the left ventricle
from the left ventricle, blood leaves the heart via the aortic semi-lunar valve and on to the aorta
between pulmnary trunk and aortic arch is ligament arteriosum what was once a hole
fetal ductus arteriosum remnant
ischemia
decreased flow of blood to vessel (low oxygen) which leads to angina pectoris
angina pectoris
chest pain
myocardial infarct
heart attack; death of cardiac muscle due to lack of blood supply. Caused by blockage of coronary artery usually due to plaque
cardiac arrest
heart stops pumping
coronary circulation
flow thru vessels in myocardium
coronary arteries
(left and right)
branch from aorta to carry oxygenated blood throughout cardiac muscle and drains into the coronary veins
coronary veins
carries de-oxygenated blood back to get oxygenated and drains into the coronary sinus
coronary sinus
(posterior) all de-oxygenated blood collected by coronary veins empties into one coronary sinus which drains into the right atrium
sinoatrial (SA) node
pacemaker; located in right atrium wall causes both atria contract “push” blood to ventricle
shortens=contracting=systole=depolarization
lengthens=relaxation=diastole=repolarization
AV (atrio-ventricular) node
(interatrial septum) slows conduction (0.1 sec) allows blood to empty to ventricle
AV bundle: Bundle of His
(interventrical septum) allows Action Potential to pass from atria to ventricles
right/left bundle branches
conducts impulses (left bundle to left atrium and right bundle to right atrium)
Purkinje fibers
(large conduction fibers)
quick to apex then up side walls
ventricles contract
Pacemaker
Controls irregular heart rhythm via electrical pulses to go back to normal
if SA node is damaged
heart beats too slow not enough blood to brain
artificial pacemaker
inherently SA node: 100 bpm
Average resting: 70/75 bpm
How does the AP spread throughout all the muscle fibers?
Gap junctions in intercalated discs
one cardiac cycle
one heart beat
typically:
2 atria contract while 2 ventricles relax then 2 ventricles contract and 2 atria relax
systole
contraction
diastole
relaxation
atrial systole
contraction both atria
ventricular systole
contraction both ventricles
resting state
cardiac cycle lasts 0.8 sec
AVE bpm at rest
70-75 bpm
when do atria contract/relax?
both atria contract at the same time and relax at the same time
when are ventricles relaxing?
when atria are contracting and vice versa
what is EKG (Electrocardiogram)
recording of currents from cardiac conduction on skin. Lets us infer what is happening in the muscle and conductive tissue
P wave
atrial depolarization —> contraction atria (contraction happens after peak)
QRS complex
onset of ventricular depolarization —> contraction of ventricles
T wave
ventricular repolarization —> ventricles start to relax
EKG is really only?
voltage over time
EKG easily measures?
heart rate
EKG infers?
abnormal rhythm and patterns, follow recovery post heart attack, and presence of living fetus
average bpm of adult
60-100 bpm
vein vs artery
Arteries carry blood away from the heart, and veins carry blood towards the heart
Mitral regurgitation
is a disorder in which the mitral valve on the left side of the heart does not close properly, leads to irregular sounds
what does it mean to have a pulse?
a measurement of the heart rate, or the number of times the heart beats per minute