Digoxin

Which of the following are brand names of digoxin? (Select all that apply) A. Lanoxin B. Digitek C. Digox D. Lanoxin XR

A. Lanoxin; B. Digitek; C. Digox

Which of the following are FDA-approved or common indications for digoxin? (Select all that apply) A. Atrial fibrillation B. Atrial flutter C. Hypertension D. Heart failure with reduced ejection fraction E. Hyperlipidemia

A. Atrial fibrillation; B. Atrial flutter; D. Heart failure with reduced ejection fraction

Which of the following dosage forms and strengths are available for digoxin? (Select all that apply) A. Oral solution 0.05 mg/mL B. Oral tablet 62.5 mcg C. Oral tablet 250 mcg D. Intravenous infusion E. Oral tablet 125 mcg

A. Oral solution 0.05 mg/mL; B. Oral tablet 62.5 mcg; C. Oral tablet 250 mcg; E. Oral tablet 125 mcg

Which of the following correctly describe the mechanism of action of digoxin? (Select all that apply) A. Improves calcium availability to myocardial contractile elements B. Enhances myocardial contractility C. Blocks calcium channels directly D. Acts as a digitalis glycoside

A. Improves calcium availability to myocardial contractile elements; B. Enhances myocardial contractility; D. Acts as a digitalis glycoside

Which of the following statements are correct regarding digoxin use in renal impairment? (Select all that apply) A. No dose adjustment is required B. Dose adjustment is necessary in renal impairment C. Renal function should be considered when dosing D. It is completely contraindicated in renal impairment

B. Dose adjustment is necessary in renal impairment; C. Renal function should be considered when dosing

Which of the following are contraindications to digoxin therapy? (Select all that apply) A. Ventricular fibrillation B. Hypersensitivity C. Atrial fibrillation D. Heart failure with reduced ejection fraction

A. Ventricular fibrillation; B. Hypersensitivity

Which of the following counseling points should be given to a patient taking digoxin? (Select all that apply) A. Take after morning meals B. Do not discontinue the drug suddenly C. Vision changes (yellow/green) may occur D. Avoid monitoring heart rate E. Frequent loose stools may occur

A. Take after morning meals; B. Do not discontinue the drug suddenly; C. Vision changes (yellow/green) may occur; E. Frequent loose stools may occur

Which of the following statements regarding boxed warnings for digoxin are correct? (Select all that apply) A. It has a boxed warning for arrhythmias B. It has no boxed warning C. It carries a boxed warning for renal toxicity D. It carries a boxed warning for cardiotoxicity

B. It has no boxed warning