Immunology - Lecture 3 - Innate Immune cells and their functions

What is the innate immune system?

A group of cells with a common anatomical origin and cell ancestor, and general molecular features

What is the first line of defense against pathogens?

What activates the immune system?

What leukocyte lineage (lymphoid or myeloid) comprises most of the cells of the innate immune system?

What do senor cells express and detect?

What does a macrophage do? and where does it reside?

How do macrophages phagocytose things, and what is expressed on macrophages?

What does a dendritic cell do? and where does it reside?

Resides in the tissue when inactivates, but when sensing a PAMP, goes to the lymph node to prime T cells

What does a neutrophil do? and where does it reside?

What do Eosinophils do? and where does it reside?

What do basophils do? and where does it reside?

What do mast cells do? and where does it reside?