Immune Cells (31.4)

Mast cells have ____ that are released into the extracellular environment

Granules

Mast cell granules are ______ mediators: Compounds that influence the tone and diameter of blood vessels

Vasoactive

Mast cells play an important response in _____ responses

allergic

Three granulocytes to know (outside of mast cells)

Eosinophils
Basophils
Neutrophils

Which granulocyte is key for worm and fungal infections?

Eosinophils

Which granulocyte is key for allergic responses?

Basophils

Which granulocyte is a phagocyte that actively engulfs and kills bacteria?

Neutrophils

What are the three phagocytes to be familiar with?

Neutrophils
Macrophages
Dendritic cells

Neutrophils are the phagocytes found in the 

bloodstream

Macrophages are the phagocytes found in

specific tissues/cells

Dendritic cells are the phagocytes found in

Skin and mucous membranes (barriers)

What are NETs?

Neutrophil extracellular traps (NETs) that trap nearby pathogens

Which phagocyte is the first responder to detecting tissue invasion, that sounds the chemical alarm (cytokines) when a microbe invades?

Macrophages

A cell that displays foreign antigens on their surface to share information with lymphocytes (T/B cells) to stimulate an adaptive response

Antigen Presenting Cell

The 3 APCs to know

Macrophages
Dendritic cells
B cells

Cells that secrete cytokines that assist in both innate and adaptive cells (briefly mentioned)

Innate lymphoid cells

Cells that detect surface patterns and destroy stressed, malignant, or virally infected host cells

Natural Killer (NK) Cells

NK cells deliver enzymes that trigger _______

apoptosis