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Define anatomy and physiology and how they are related
Anatomy: Study of the body and its parts
Physiology: Study of the body parts' functions
Homeostasis
All body systems working together to maintain a stable internal environment
Negative feedback & its relation to Homeostasis
The response of the effector negates the stimulus
Negative feedback brings the body back into homeostasis
Up/Down
Superior/Inferior
"Heads"/"Tails"
Cranial/Caudal
Front/Back
Anterior/Posterior
Middle/To The Side
Proximal/Distal
Towards/Away From Trunk
Medial/Lateral
Major Ventral Body Cavities
Thoracic
Abdominopelvic
Anatomical Planes
Frontal/coronal
Sagittal (Hot Dog Fold)
Transverse (Hamburger Fold)
Eye
Occular/Optic
Chin
Mental
Armpit
Axillary
Front of Elbow
Antecubital
Navel/Bellybutton
Umbellical/Navel
Groin ("V-Lines")
Inguinal
Thigh
Femoral
Foot
Pedal
Ear
Otic
Chest
Thoracic
Arm
Humeral
Back of Elbow
Olecranal
Back
Dorsal
Loins/Lower Back
Lumbar
Calf
Sural
Sole
Plantar
Cheeks (face)
Buccal
Shoulder
Acromial
Forearm
Antebrachial
Wrist
Carpal
Buttocks
Gluteal
Kneecap
Patellar
Ankle
Tarsal
Big Toe
Hallux
Head
Cephallic
Hand
Manual
Thumb
Pollux
Fingers
Digits
Back of Knee
Popliteal
Heel
Calcaneal
Toes
Phalangeal
Abdominal Quadrants
Right Upper Quandrant (Liver/Gallbladder)
Left Upper Quadrant
(Stomach/Spleen)
Right Lower Quadrant
(Small Intestine/Appendix)
Left Lower Quadrant
(Urinary)
Abdominal Regions
Right/Left Hypochondriac
Right/Left Lumbar
Right/Left Inguinal
Epigastric
Umbellical
Hypogastric (Pubic)
Levels of Organization from Atom to Organism
Atom
Organ
Organ Tissue
Organism
At what levels are things considered "living?"
Organism
Atom
Smallest unit of matter
Element
Molecule w/ 1 Type of Element
Compound
Molecule w/ 2+ Types of Elements
Full names for chemical symbols covered in lecture:
C, Ca, Na, F, H, K, Cl, I, O, P, Mg, Zn, N, S, Fe, Co
Carbon
Calcium
Sodium
Fluorine
Hydrogen
Potassium
Chlorine
Iodine
Oxygen
Phosphorous
Magnesium
Zinc
Nitrogen
Sulfur
Iron
Cobalt
Subatomic Particles & their relative size/charge/arrangement in an atom
Protons: 1 Mass Unit/Nucleus
Neutrons: 1 Mass Unit/Nucleus
Electrons: 0.00055 Mass Units/Surrounding Nucleus
How changing the # of protons/neutrons/electrons does to an atom?
(Change of # Protons? Change of # Neutrons? Change of # Electrons?)
Change in Element
Isotopes
Ion
Types of Chemical Bonds and how they differ
Synthesis: A + B -> AB
Decomposition: AB -> A + B
Exchange: AB + CD -> AC + BD
Reversible: On/Off Relationship
How Polar and Non-Polar bonds affect hydrophobicity
Polar=Hydrophillic
Non-Polar=Hydrophobic
Elements associated with Hydrogen Bonding
Nitrogen
Oxygen
Flourine
Enzymes & their effects on chemical reactions
Protein catalysts that speed up chemical reactions
Acidity, pH, & Protons
pH: Scale used to measure proton concentration
pH of Bodily Fluids (e.g. Stomach Acid, Blood, Urine)
Stomach Acid= Extremely Acidic
Blood=Neutral
Urine=4.5-8
4 Major Types of Biological Macromolecules
Protein
Fats/Lipids
Carbs/Saccarhides
Nucleic Acids
Which of the Biological Macromolecules form polymers in the body?
Carbs
Proteins
Nucleic Acids
Monosaccharides, Disaccharides, & Polysaccharides, & examples
• Glucose/Fructose/Galactose
Sucrose/Maltose
Glycogen/Starch/Cellulose
Examples of Lipids
Fatty Acids
Steroids
Glycerides
Eiconsenoids
Phospholipids
Glycolipids
Peptide Bonds
The type of bond that links Amino Acids
The 5 Major Nucleic Acids
Thymine (DNA)
Adenine (DNA/RNA)
Cytosine (DNA/RNA)
Guanine (DNA/RNA)
Uracil (RNA)
DNA vs. RNA - Similarities & Differences
DNA has deoxybiroses & phosphate; has genetic code
RNA has ribose & phosphate
The 3 main parts of a nucleotide
Phosphate
Sugar
Base
Plasma membrane composition & function
Lipid bilayer containing phospholipids, steroids, proteins, and carbohydrates
Glycolipids; What can/can't pass through?
Carbs + Lipids
Can Pass=Small Molecules
Non-Polar Compounds
Can't Pass=Large Molecules
Highly Polar Compounds
Ions
Glycoproteins
Integral: Inside Membrane
Peripheral: Bound to inner/outer surface
Diffusion
High -> Low Concentration
Facilitated Diffusion
High -> Low w/ HELP (from transport proteins)
Osmosis
High -> Low H2O Concentration (to balance out solute)
Involves semi-permeable membrane
Primary Active Transport
ATP Breakdown provides energy; Sodium/Potassium Exchange Pump
Secondary Active Transport
No ATP; Sodium/Calcium Exchanger
Endocytosis
The taking in of matter by a living cell by invagination of its membrane to form a vacuole
Exocytosis
A process by which the contents of a cell vacuole are released to the exterior through fusion of the vacuole membrane with the cell membrane.
Cytoplasm
Everything in the cell except for the nucleus
Cytosol
Liquid Part
Cytoskeleton
Non-Membranous
Gives cells shape & helps organize its parts
Parts of Cytoskeleton
Microfilaments
Intermediate Filaments
Microtubules
Centrioles
Non-Membranous
Assists in cell division
Centrosome
Non-Membranous
Cytoplasm surrounding centriole
Cilia
Non-Membranous
Beat & Wave
Moves particles
Microvilli
Non-Membranous
Increase surface area for absorption
Attaches to cytoskeleton
Different/smaller than cilia
Ribosomes
Non-Membranous
Synthesizes polypeptides
Proteasomes
Non-Membranous
Breaks down proteins for recycling
Endoplasmic Reticulum
Membranous
Involved in protein/lipid synthesis
Nearby the nucleus
Golgi Apparatus
Membranous
Stores & packages secretory products/lysosomal enzymes
Lysosome
Non-Membranous
Intracellular removal of damaged organelles/pathogens
Peroxisomes
Membranous
Contains enzymes
Produces hydrogen peroxide
Breaks down fatty acids/organic compounds
Detoxify by changing toxic chemicals
Mitochondria
Membranous
Produces 95% of the cell's ATP
The Nucleus & it's contents
Largest Organelle; The cell's "brain"
DNA
Nucleoplasm
Nuclear matrix
Nucleoli
Nucleosomes
Phases of the Cell Cycle
G1 (Cell Growth)
S (Synthesis)
G2 (Growth)
M (Mitosis)
When is DNA replicated?
During the "S" Phase
When does the cell undergo cell division?
Mitosis
Stages of Mitosis
Interphase (I'll)
Prophase (Pass)
Metaphase (My)
Anaphase (Anatomy)
Telophase (Test)
Which Nucleic Acids bond with each other?
A T (A Teacher)
A U (Asks U)
G C (to Get Coffee)
Transcription
Creates mRNA transcripts from DNA
Still has info from DNA
Translation
mRNA (Recipe) -> Ribosomes (chef) -> Amino Acids/Peptides (Food)
Apical Tissue
Top Layer
Basal Tissue
Bottom Layer