Quant Chem- Exam 1

Qualitative Analysis

For example: intifying the products of a rxn, IR/NMR Spectroscopy

Quantitative Analysis

For example: concentrations, differences

Characterization Analysis

Chemical structure, equilibrium constants

Fundamental Analysis

Improving the understanding of the theory itself and its limitations

Molecular Spectroscopy

Absorption of components measured in their molecular states. Much broader, interference is common. Determines a range of organic and inorganic compounds

Atomic Spectroscopy

Molecules blown apart to measure elemental concentrations. Narrow features, spectral overlap rare. Measures metal concentrations.

10-1000. DL

Flame absorption DL

.01-1 DL

GFAA DL

.1-10 DL

ICP OES DL

.00001-.0001 DL

ICP MS DL

Very few spectral interference

FAA, GFAA interference

Many spectral interference

ICP OES interference

Few spectral interference

ICP MS interference

Large sample volume

FAA sample

Very small sample volume

GFAA sample

Medium sample volume

ICP MS and OES sample

Spectral Interference

Something in the sample matrix that absorbs or emits light at a similar wavelength to the analyte to cause a false negative/positive, more common in molecular absorption

Chemical interference

Something in the sample matrix that chemically reacts with the analyte to change the behavior and quantification in the analysis, more common in atomic absorbance

CI t test

Compares mean with confidence, 1 known value

Two sample t test

Compare two groups of data to check for overlap

Paired t test

Compares individual observations measured two different ways, each sample not the same