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Clinical Manifestation & Rabid Animal Exposure History
Basis of rabies diagnosis
Pathognomonic Hydrophobia & Aerophobia
Straightforward rabies diagnosis
Paralytic Rabies & Atypical Presentations
Difficult to make a clinical rabies diagnosis
Fluorescent Antibody Testing, Polymerase Chain Reaction, Serology, Histologic Findings
4 Rabies Confirmatory Tests
Postexposure Prophylaxis
initiated after a recognized exposure & before any symptoms or signs develop
Critical Care Units
Have aggressive management with supportive care
Wound Cleansing
Done immediately & thoroughly to reduce rabies likelihood
10 Minutes
The Amount of time to wash rabies wounds
Pregnancy & Infancy
Not contraindications to PEP with modern culture cell vaccine & RIG
Rabies Vaccination & Rabies Immune Globulin
Can be given to babies born to rabid mothers upon birth
14 Days
The Amount of time after the bite needed for the biting animal to remain healthy & alive with no signs of rabies when PEP is no longer needed
Post-Exposure Prophylaxis
antirabies prophylaxis should be administered after an exposure
Pre-Exposure Prophylaxis
Vaccination should be given to individuals who are at high risk of getting rabies