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Flashcards covering key vocabulary and concepts from the lecture on the urinary system.
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Urinary system
Removes most metabolic wastes produced by body's cells.
Kidneys
Paired organs that produce urine by removing metabolic wastes from circulation.
Urinary tract
Eliminates urine; consists of ureters, urinary bladder, and urethra.
Urination (micturition)
Process of eliminating urine from the body.
Excretion
Removal of metabolic wastes from body fluids.
Elimination
Discharge of wastes from the body.
Homeostatic regulation
Regulation of volume and solute concentration of blood.
Erythropoietin
Hormone released by kidneys that stimulates red blood cell formation.
Renin
Enzyme involved in regulating water and sodium balance.
Calcitriol
Active form of vitamin D that regulates calcium ion levels.
Renal capsule
Layer of collagen fibers covering the outer surface of each kidney.
Perinephric fat
Thick layer of adipose tissue surrounding the fibrous capsule of the kidney.
Renal fascia
Dense fibrous outer layer that anchors the kidney to surrounding structures.
Hilum
Medial indentation of the kidney where blood vessels and nerves enter and exit.
Renal sinus
Internal cavity within the kidney lined by the fibrous capsule.
Renal cortex
Superficial region of the kidney in contact with the fibrous capsule.
Renal pyramids
Triangular structures in the renal medulla that produce urine.
Renal column
Tissue bands that separate adjacent renal pyramids.
Kidney lobe
Consists of a renal pyramid, overlying renal cortex, and adjacent renal columns.
Minor calyx
Structure that collects urine from renal papillae.
Major calyx
Formed by several minor calyces; funnels urine into the renal pelvis.
Renal pelvis
Funnel-shaped chamber that collects urine from the major calyces and drains into the ureter.
GFR (Glomerular Filtration Rate)
Amount of filtrate produced by the kidneys each minute, approximately 125 mL.
Filtration membrane
Consists of fenestrated endothelium, basement membrane, and foot processes of podocytes.
Podocytes
Cells in the visceral layer of the glomerular capsule that wrap around glomerular capillaries.
Renal corpuscle
Spherical structure consisting of the glomerular capsule and glomerulus.
Nephron
Microscopic functional unit of the kidney, consisting of renal corpuscle and renal tubule.
Proximal convoluted tubule (PCT)
First segment of the renal tubule, primarily involved in reabsorption.
Distal convoluted tubule (DCT)
Third segment of the renal tubule, involved in reabsorption and secretion.
Juxtaglomerular complex (JGC)
Regulates blood pressure and filtrate formation.
Collecting ducts
Receive fluid from many nephrons and transport it to the renal pelvis.
Cortical nephrons
Nephrons primarily located within the cortex of the kidney.
Juxtamedullary nephrons
Nephrons that extend deep into the medulla, involved in the concentration of urine.
Urea
Most abundant organic waste, primarily from protein breakdown.
Creatinine
Waste product from the breakdown of creatine phosphate in muscles.
Uric acid
Waste product from the recycling of nitrogenous bases of RNA.
Filtration
Process where blood pressure forces water and solutes across the glomerular capillaries.
Reabsorption
Movement of water and solutes from filtrate back into the blood.
Secretion
Transport of solutes from blood into the filtrate.
Hydrostatic pressure
Fluid pressure that drives glomerular filtration.
Colloid osmotic pressure
Pressure exerted by proteins in the blood that draws fluid back into the capillaries.
Renin-angiotensin-aldosterone system (RAAS)
Hormonal system that regulates blood pressure and fluid balance.
Atrial natriuretic peptide (ANP)
Hormone produced by the heart that decreases blood pressure and increases GFR.
Ureters
Muscular tubes that transport urine from kidneys to the urinary bladder.
Urinary bladder
Hollow muscular organ that temporarily stores urine.
Detrusor muscle
Muscle layer of the bladder that contracts to expel urine.
Urethra
Tube that transports urine from the bladder to the outside of the body.
Internal urethral sphincter
Muscular structure that provides involuntary control of urine discharge.
External urethral sphincter
Skeletal muscle valve that provides voluntary control of urination.
Micturition reflex
Neural reflex that stimulates contraction of the bladder and relaxation of the sphincters.
Urine composition
Reflects filtration, reabsorption, and secretion activities of nephrons.
Blood urea nitrogen (BUN) test
Measures urea in blood to assess kidney function.
Creatinine clearance
Measurement comparing creatinine levels in urine and blood to estimate GFR.
Pyelogram
Image of urinary system obtained via X-ray after dye administration.
Transitional epithelium
Type of epithelium lining the urinary bladder and ureters, allowing stretching.
Peristaltic contractions
Muscular movements that propel urine towards the urinary bladder.
Incontinence
Inability to control urination voluntarily.
Glucosuria
Presence of glucose in urine, indicating exceedance of renal threshold.
Aminoaciduria
Presence of amino acids in urine, indicative of a renal threshold issue.
Reabsorption at PCT
Process where 60-70% of filtrate is reabsorbed, including nutrients and electrolytes.
Sodium ion reabsorption
Key process in renal tubule function; often linked to water movement.