Double blind
________: participants and assessors are unaware of what kind of treatment participants are getting.
Longitudinal designs
________: study one group of people over time.
Competence
________: ability to provide consent.
Research Design
________: a method to test hypotheses.
Proband
________: The person who has the trait of interest (e.g.
Placebo
________: some participants are given an inactive treatment (e.g., sugar pill), but participants dont know which treatment they are getting.
Endophenotype
________: genetic mechanism that contributes to problems causing certain symptoms.
Genetic linkage studies occur in
groups of people who all have the trait of interest.
Clinical trial
________: experiment designed to evaluate the effectiveness of a treatment.
Hypotheses in science are formulated so that
they are testable.
Phenotype
________: observable characteristics (e.g., eye color, degree of shyness)
Comprehension
________: understanding about benefits and risks of participation.
Placebo effect
________: something changes simply because the participant expects the change to occur (e.g., expecting to feel better when taking an inactive pill)
Voluntarism
________: lack of coercion.
Correlation
________: assess the degree to which levels of certain variables are linked to levels of other variables.
Health promotion
________: increasing healthy behavior in entire population (even people not at risk for developing disorders)
Control group
________: provides a comparison point.
External validity
________: extent to which results of a study are generalizable to the population its studying.
Familial aggregation
________: tendency of a disorder to run in families.
Association studies occur in
people with and without the trait of interest
Universal prevention
________: target specific risk factors but not specific people.
Independent variable
________: the variable that causes or influences behavior.
Research Design
a method to test hypotheses
Independent variable
the variable that causes or influences behavior
Dependent variable
the behavior influenced by the independent variable
Internal validity
extent to which results of a study are due to the independent variable
External validity
extent to which results of a study are generalizable to the population its studying
Statistical methods
branch of mathematics
Statistical significance
asks are results due to chance
Clinical significance
asks are results clinically meaningful
Correlation
assess the degree to which levels of certain variables are linked to levels of other variables
Examples
AIDS, trauma following disaster
Clinical trial
experiment designed to evaluate the effectiveness of a treatment
Example
Administering a drug
Control group
provides a comparison point
Placebo
some participants are given an inactive treatment (e.g., sugar pill), but participants dont know which treatment they are getting
Double-blind
participants and assessors are unaware of what kind of treatment participants are getting
Placebo effect
something changes simply because the participant expects the change to occur (e.g., expecting to feel better when taking an inactive pill)
Start treatment at different times in different conditions (e.g., in home vs. school settings)
see if changes occur in conjunction with introduction of treatment
Genotype
genetic makeup
Phenotype
observable characteristics (e.g., eye color, degree of shyness)
Endophenotype
genetic mechanism that contributes to problems causing certain symptoms
Example
Group of genes responsible for impairing working memory in schizophrenia
Proband
The person who has the trait of interest (e.g
Familial aggregation
tendency of a disorder to run in families
Issue of shared environment
families usually live together, so similarities may be due to environmental factors as well as genetics
Sibling pairs separated after birth
Do they show similarities even if they were raised in different environments
Can be combined with adoption studies
If identical twins are both adopted separately and raised apart, shared outcomes are more attributable to genetics
Health promotion
increasing healthy behavior in entire population (even people not at risk for developing disorders)
Universal prevention
target specific risk factors but not specific people
Selective prevention
targets groups of people at risk
Indicated prevention
targets specific individuals who are showing early signs of a disorder
Cross-sectional designs
take a cross section of the population at different age groups
Longitudinal designs
study one group of people over time
Have to take into account specific experiences of the generation being studied (cross
generational effect)
Competence
ability to provide consent
Voluntarism
lack of coercion
Full information
necessary information to make an informed decision
Comprehension
understanding about benefits and risks of participation
Informed consent became more widely discussed after N
Nazis had forced people to participate in research in WWII
Ethics are determined by
institutional review board (IRBs) and and the APA ethics code
Sometimes, needs of science are at odds with
needs of research participants
Research ethics determine
the degree to which each should be prioritized
Replication of research is critical -
protects against fluke results
Research programs allows for
more nuanced, complete picture of a phenomenon
Components of a research program:
set of interrelated research questions
draw on several methodologies in finding answers
conducted in stages often involving replication
Difficulties in cross cultural research:
definitions of abnormal behavior
variance in presentation
availability of valid assessment instruments may be limited
Cross cultural research increases understanding of
etiologies, symptom presentations, and treatments
Cross cultural research helps people overcome
ethnocentric views
With longitudinal designs, you have to take into account
specific experiences of the generation being studied (cross-generational effect)
Cross-sectional designs:
take a cross section of the population at different age groups and compare cohorts on traits of interest
Universal prevention:
target specific risk factors but not specific people
Selective prevention:
targets groups of people at risk
Indicated prevention:
targets specific individuals who are showing early signs of a disorder
If the genetic marker tends to co-occur with the trait,
conclude that the trait is probably caused in part by genes that are in close proximity to the genetic marker
Genetic linkage and association studies:
examine known genetic markers and compare them against the trait being studied
Twin studies can be combined with
adoption studies
If identical twins are both adopted separately and raised apart,
shared outcomes are more attributable to genetics
Compare identical to fraternal twins:
if a trait is genetic, expect to see greater concordance in identical twins compared to fraternal twins
Adoption studies are one way to
separate the effects of the environment
Issue of shared environment:
families usually live together, so similarities may be due to environmental factors as well as genetics
If there is a genetic influence in family studies,
expect to see the trait more in first degree relatives compared to second degree
Genotype:
genetic makeup