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Opioid overdose deaths
Rose significantly after 2010 following changes in the marketing and availability of OxyContin.
Purdue Pharma
Pharmaceutical company known for marketing OxyContin and involved in controversial practices around opioid prescriptions.
5th vital sign
Pain was promoted as the 5th vital sign by Sacklers, indicating a need to assess pain alongside traditional vital signs.
OxyContin
A prescription opioid medication that was marketed heavily by Purdue Pharma; characterized by time-release coating.
Pseudoaddiction
A condition where patients appear to be addicted to opioids but are actually in pain and require increased dosages.
Curtis Wright
FDA official who collaborated with Purdue Pharma on the licensing of OxyContin and later took a lucrative job with them.
Astroturf groups
Organizations that appear to be grassroots but are secretly funded by corporations, like the American Pain Foundation funded primarily by Purdue.
Opiophobia
The fear of prescribing opioids due to concerns about addiction and misuse.
Suboxone
Medication used to treat opioid use disorder, which has restrictions on concurrent substance use.
Methadone
Opioid used in treatment programs, often requiring in-person administration at clinics.
Sackler family
Owners of Purdue Pharma, involved in various controversies regarding the opioid crisis and philanthropy.
Settlement
The legal conclusion involving Purdue in which $10.4 billion was transferred to the Sacklers before the bankruptcy.
Emerging markets
Regions like India and China that Purdue Pharma aimed to expand opioid sales into, with significant financial strategies.
Nan Goldin’s campaign
Advocacy movement that pressured major art institutions to remove the Sackler name due to their involvement in the opioid crisis.