Brain Tumor Flashcards

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Flashcards reviewing different types of brain tumors, TSEs and misfolded proteins.

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14 Terms

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Gliomas

Tumors arising from glial cells.

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Glioblastoma

A type of glioma arising from glial cells; specific type not specified in notes.

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Astrocytoma

A type of glioma arising from astrocytes.

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Ependymoma

A type of glioma arising from ependymal cells from the ventricles.

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Oligodendrocytoma

A type of glioma arising from oligodendrocytes.

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Meningioma

Tumor arising from cells of the meninges.

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Neurinoma

Tumor arising from Schwann cells or cells of connective tissue covering cranial nerves.

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Angioma

Tumor arising from cells of blood vessels.

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Pinealoma

Tumor arising from cells of the pineal gland.

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PrPSc

Infected prion; the sequence of amino acids of normal prion protein (PrPc) and infectious prion (PrPSc) are identical, but have different effects.

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PrPc

Normal prion protein; the sequence of amino acids of normal prion protein (PrPc) and infectious prion (PrPSc) are identical, but have different effects.

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Caspase

A “Killer enzyme” that plays role in apoptosis, or programmed cell death – acumulation of misfolded, abnormal proteins signals for apoptosis and production of capases.

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Apoptosis

Accumulation of misfolded, abnormal proteins signals for apoptosis and production of caspases.

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Misfolded Proteins

Functions of proteins determined by three-dimensional shapes (way the protein is folded).