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Flashcards reviewing different types of brain tumors, TSEs and misfolded proteins.
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Gliomas
Tumors arising from glial cells.
Glioblastoma
A type of glioma arising from glial cells; specific type not specified in notes.
Astrocytoma
A type of glioma arising from astrocytes.
Ependymoma
A type of glioma arising from ependymal cells from the ventricles.
Oligodendrocytoma
A type of glioma arising from oligodendrocytes.
Meningioma
Tumor arising from cells of the meninges.
Neurinoma
Tumor arising from Schwann cells or cells of connective tissue covering cranial nerves.
Angioma
Tumor arising from cells of blood vessels.
Pinealoma
Tumor arising from cells of the pineal gland.
PrPSc
Infected prion; the sequence of amino acids of normal prion protein (PrPc) and infectious prion (PrPSc) are identical, but have different effects.
PrPc
Normal prion protein; the sequence of amino acids of normal prion protein (PrPc) and infectious prion (PrPSc) are identical, but have different effects.
Caspase
A “Killer enzyme” that plays role in apoptosis, or programmed cell death – acumulation of misfolded, abnormal proteins signals for apoptosis and production of capases.
Apoptosis
Accumulation of misfolded, abnormal proteins signals for apoptosis and production of caspases.
Misfolded Proteins
Functions of proteins determined by three-dimensional shapes (way the protein is folded).