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What is a joint?
Place where 2 or more bones make contact
Why is synovium vascular?
Has a vital role in providing nutrients to articular cartilage (which is avascular)
Why is it painful when synovium is inflammed?
It is innervated
What does synovium produce
Synovial fluid
Which cells are found in synovium?
Type A
Type B
Connective tissue
Type A cells in synovium
Similar to macrophages
Removes debris from synovial fluid
Type B cells in synovium
Similar to fibroblasts
Produce extramatrix proteins in synovial fluid e.g. hylauronic acid, collagen, fibronectin
Connective tissue in synovium
Fibrous/fatty tissue which makes up bulk of synovium
Role of synovial fluid
Lubricates joint via diffusion
Type of fluid is synovial fluid?
Viscous fluid of plasma ultrafiltrate
Contents of synovial fluid
Hyaluronic acid
Lubracin
Proteinases
Collagenases
Prostaglandins
Synovitis
Inflammed synovium which infiltrates and damages surrounding tissues (bones, tendons, articular cartilage)