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Corticotropin-releasing hormone (CRH)
Synthesized:
hypothalamus
Corticotropin-releasing hormone (CRH)
Released:
hypothalamus
Corticotropin-releasing hormone (CRH)
Target cells:
anterior pituitary
Corticotropin-releasing hormone (CRH)
Effects:
causes the release of ACTH
Gonadotropin-releasing hormone (GnRH)
Synthesized:
hypothalamus
Gonadotropin-releasing hormone (GnRH)
Released:
hypothalamus
Gonadotropin-releasing hormone (GnRH)
Target cells:
anterior pituitary
Gonadotropin-releasing hormone (GnRH)
Effects:
causes the release of FSH and LH
Growth hormone-releasing hormone (GHRH)
Synthesized:
hypothalamus
Growth hormone-releasing hormone (GHRH)
Released:
hypothalamus
Growth hormone-releasing hormone (GHRH)
Target cells:
anterior pituitary
Growth hormone-releasing hormone (GHRH)
Effects:
causes the release of GH
Prolactin-inhibiting hormone (PIH)
Synthesized:
hypothalamus
Prolactin-inhibiting hormone (PIH)
Released:
hypothalamus
Prolactin-inhibiting hormone (PIH)
Target cells:
anterior pituitary
Prolactin-inhibiting hormone (PIH)
Effects:
inhibits the release of PRL
Somatostatin
Synthesized:
hypothalamus
Somatostatin
Released:
hypothalamus
Somatostatin
Target cells:
anterior pituitary
Somatostatin
Effects:
inhibits the release of GH and TSH
Thyrotropin-releasing hormone (TRH)
Synthesized:
hypothalamus
Thyrotropin-releasing hormone (TRH)
Released:
hypothalamus
Thyrotropin-releasing hormone (TRH)
Target cells:
anterior pituitary
Thyrotropin-releasing hormone (TRH)
Effects:
causes the release of TSH and PRL
Adrenocorticotropic hormone (ACTH)
Released:
anterior pituitary
Adrenocorticotropic hormone (ACTH)
Synthesized:
anterior pituitary
Adrenocorticotropic hormone (ACTH)
Target cells:
adrenal cortex
Adrenocorticotropic hormone (ACTH)
Effects:
causes the release of glucocorticoids
Follicle-stimulating hormone (FSH)
Synthesized:
anterior pituitary
Follicle-stimulating hormone (FSH)
Released:
anterior pituitary
Follicle-stimulating hormone (FSH)
Target cells:
ovaries, testes
Follicle-stimulating hormone (FSH)
Effects:
growth of ovarian follicles and secretion of estrogen, sperm production
Growth hormone (GH)
Synthesized:
anterior pituitary
Growth hormone (GH)
Released:
anterior pituitary
Growth hormone (GH)
Target cells:
liver, bone, cartilage, muscle, fat
Growth hormone (GH)
Effects:
widespread tissue growth
Luteinizing hormone (LH)
Synthesized:
anterior pituitary
Luteinizing hormone (LH)
Released:
anterior pituitary
Luteinizing hormone (LH)
Target cells:
ovaries, testes
Luteinizing hormone (LH)
Effects:
ovulation, maintenance of corpus luteum, testosterone secretion
Prolactin (PRL)
Synthesized:
anterior pituitary
Prolactin (PRL)
Released:
anterior pituitary
Prolactin (PRL)
Target cells:
mammary glands
Prolactin (PRL)
Effects:
milk synthesis
Thyroid-stimulating hormone (TSH)
Synthesized:
anterior pituitary
Thyroid-stimulating hormone (TSH)
Released:
anterior pituitary
Thyroid-stimulating hormone (TSH)
Target cells:
thyroid gland
Thyroid-stimulating hormone (TSH)
Effects:
growth of thyroid, secretion of thyroid hormone
Antidiuretic hormone (ADH)
Synthesized:
hypothalamus
Antidiuretic hormone (ADH)
Released:
posterior pituitary
Antidiuretic hormone (ADH)
Reflex that triggers release:
baroreceptors detect decrease in blood volume, osmoreceptors detect change in blood osmolarity
Antidiuretic hormone (ADH)
Target cells:
kidneys
Antidiuretic hormone (ADH)
Effects:
water retention
Oxytocin (OT)
Synthesized:
hypothalamus
Oxytocin (OT)
Released:
posterior pituitary
Oxytocin (OT)
Reflex that triggers release:
pressure on cervix, suckling
Oxytocin (OT)
Target cells:
uterus, mammary glands
Oxytocin (OT)
Effects:
labor contractions, milk release, mother-infant bonding
Aldosterone
Synthesized:
adrenal cortex
Aldosterone
Released:
adrenal cortex
Aldosterone
Target cells:
kidney
Aldosterone
Effects:
promotes sodium and water retention and potassium excretion, maintains blood pressure and volume
Calcitonin
Synthesized:
thyroid gland
Calcitonin
Released:
thyroid gland
Calcitonin
Target cells:
bone
Calcitonin
Effects:
stimulates bone deposition
Cortisol
Synthesized:
adrenal cortex
Cortisol
Released:
adrenal cortex
Cortisol
Target cells:
most tissues
Cortisol
Effects:
stimulate fat and protein catabolism, gluconeogenesis, stress resistance, and tissue repair
Epinephrine
Synthesized:
adrenal medulla
Epinephrine
Released:
adrenal medulla
Epinephrine
Target cells:
most tissues
Epinephrine
Effects:
promote alertness, mobilize organic fuels, raise metabolic rate, stimulate circulation and respiration, increase blood glucose level, inhibit insulin secretion and glucose uptake by insulin-dependent organs
Erythropoietin
Synthesized:
liver
Erythropoietin
Released:
liver
Erythropoietin
Target cells:
red bone marrow
Erythropoietin
Effects:
promotes red blood cell production, increases oxygen-carrying capacity of blood
Estradiol/estrogen
Synthesized:
ovaries
Estradiol/estrogen
Released:
ovaries
Estradiol/estrogen
Target cells:
many tissues
Estradiol/estrogen
Effects:
stimulates female reproductive development and adolescent growth, regulates menstrual cycle and pregnancy, prepares mammary glands for lactation
Glucagon
Synthesized:
alpha cells of pancreas
Glucagon
Released:
alpha calls of pancreas
Glucagon
Target cells:
primarily liver
Glucagon
Effects:
stimulates amino acid absorption, gluconeogenesis, glycogen and fat breakdown, raises blood glucose and fatty acid levels
Insulin
Synthesized:
beta cells of pancreas
Insulin
Released:
beta cells of pancreas
Insulin
Target cells:
most tissues
Insulin
Effects:
stimulates glucose and amino acid uptake, lowers blood glucose level, promotes glycogen, fat and protein synthesis
Melatonin
Synthesized:
pineal gland
Melatonin
Released:
pineal gland
Melatonin
Target cells:
brain
Melatonin
Effects:
may influence mood and sexual maturation
Parathyroid hormone
Synthesized:
parathyroid glands
Parathyroid hormone
Released:
parathyroid glands
Parathyroid hormone
Target cells:
bone, kidneys, small intestine
Parathyroid hormone
Effects:
raises blood calcium level by stimulating bone resorption and inhibiting deposition, reducing urinary calcium excretion, enhancing calcitriol synthesis
Progesterone
Synthesized:
ovaries
Progesterone
Released:
ovaries