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lacteal
the lymphatic vessels of the small intestine that absorb digested fats. part of villi.
interstitial fluid
plasma from arterial blood that flows out of the arterioles and into the capillaries, and then flows into the spaces between the cells of the tissues. delivers nutrients, oxygen, hormones to cells.
lymph
10% of interstitial fluid, contains electrolytes and proteins. collects protein molecules created within cells as it leaves, enters capillaries and travels to neck, protects against infections
lymphatic circulatory system
point of origin -> base of neck -> filtered by lymph nodes located in lymphatic vessels
lymphatic capillaries
Small, open-ended lymph vessels that act like drain pipes which picks up lymph at tissues throughout the body
lymphatic vessels and ducts
the capillaries, vessels, and ducts that return lymph from the tissues to the venous bloodstream
thoracic duct
receives lymph from the left side of the head, neck, chest, abdomen, left arm, and lower extremities. empties into subclavial vein
lymph node
a small knob of tissue in the lymphatic system that filters lymph, trapping bacteria and other microorganisms that cause disease
lymphocytes
leukocytes formed in bone marrow. undergo maturation and differentiation throughout the body, letting them fight off infection
natural killer cells (NK cells)
play an important role in the killing of cancer cells and cells infected by viruses
B cells (B lymphocytes)
specialized lymphocytes that produce antibodies; most effective against viruses and bacteria that are circulating in the blood
plasma cells
Cells that develop from B cells and produce large volume of antibodies.
T cells (T lymphocytes)
specialized white blood cells that receive markers in the thymus, are responsible for cellular immunity, and assist with humoral immunity
cytokines
proteins secreted by cytotoxic T cells that act as intracellular signals to begin immune response (includes interferons and interleukins)
types of tonsils
adenoids (nasopharyngeal), palatine, lingual
vermiform appendix (appendix)
hangs from the lower portion of the cecum; consists of lymphoid tissue
spleen
mass of lymphoid tissue. filters blood, forms lymphocytes and monocytes, destroys worn-out erythrocytes, stores extra erythrocytes
antigen
any substance regarded as being foreign in the body (viruses, bacteria, toxins, transplanted tissues)
antibody
a substance produced by the body that destroys or inactivates an antigen that has entered the body
immunoglobulins
bind with specific antigens in the antigen-antibody response, secreted by plasma cells
5 types of immunoglobulins
IgG, IgA, IgM, IgE, IgD
phagocytes
a type of cell within the body capable of engulfing and absorbing bacteria and other small cells and particles. (monocytes, macrophages, dendritic cells)
complement system
proteins in the blood that help antibodies and T cells kill their target
lymphoscintigraphy
a radioactive diagnostic test that is performed to detect damage or malformations of the lymphatic vessels
lymphedema
swelling of the tissues due to an abnormal accumulation of lymph fluid within the tissues. often associated w infections
primary vs secondary lymphedema
Primary: Due to congenital absence of ducts, or an obstruction. Secondary: Due to surgical removal, or radiation induced destruction.
systemic reaction (anaphylaxis)
also anaphylactic shock; severe response to an allergen; can quickly be fatal
HIV (human immunodeficiency virus)
Human immunodeficiency virus, the retrovirus that attacks the T cells and causes AIDS.
opportunistic infection
caused by a pathogen that does not normally produce an illness in healthy humans
ELISA (enzyme-lined immunosorbent assay) and Western blot test
blood test that screens for presence of HIV antibodies
synthetic immunoglobulins
used as a postexposure preventive measure against certain viruses
cytotoxic drug
medication that kills or damages cells
septic shock
a serious condition that occurs when an overwhelming bacterial infection affects the body. causes vital organs to not function/fail completely
Methicillin-resistant Staphylococcus aureus (MRSA)
a strain of the bacterium Staphylococcus aureus that has become resistant to most antibiotics
toxoplasmosis
a parasite that is most commonly transmitted from pets to humans by contact with contaminated animal feces
measles
acute, highly contagious infection that is transmitted by respiratory droplets of the rubeola virus
mumps
acute viral infection that is characterized by the swelling of the parotid glands
rubella
a viral infection characterized by a low-grade fever, swollen glands, inflamed eyes, and a fine, pink rash
Cytomegalovirus (CMV)
herpes-type virus that usually causes disease when the immune system is compromised, most often a silent infection
varicella
chicken pox
herpes zoster (shingles)
a disease that involves a painful skin eruptions following path of inflamed nerve
infectious mononucleosis (mono)
an infection caused by the Epstein-Barr virus (EBV) that is characterized by fever, a sore throat, and enlarged lymph nodes
angiogenesis
tumour supports its growth by creating its own blood supply
metastisize
the process by which cancer spreads from one place to another. The cancer moves from the primary site and metastasizes (spreads) to a secondary site.
soft-tissue sarcomas
cancers of the muscle, fat, fibrous tissue, blood and lymphatic vessels, or other supporting tissue, including the synovial tissues that line the cavities of joints
liquid-tissue sarcomas
arise from blood and lymph
carcinoma
a malignant tumor that occurs in epithelial tissue
hard-tissue sarcomas
sarcomas that arise from bone or cartilage
Hodgkin's lymphoma
distinguished from other lymphomas by the presence of large, cancerous lymphocytes known as Reed-Sternberg cells
infiltrating ductal carcinoma
starts in the milk duct, breaks through the wall of that duct, and invades the fatty breast tissue
infiltrating lobular carcinoma
cancer that starts in the milk glands, breaks through the wall of the gland, and invades the fatty tissue of the breast
radial mastectomy
the surgical removal of an entire breast and many of the surrounding tissues
antineoplastic
medication that blocks the development, growth, or proliferation of malignant cells
brachytherapy
the use of radioactive materials in contact with or implanted into the tissues to be treated
teletherapy
radiation therapy administered at a distance from the body
adjuvant therapy
used after the primary treatments have been completed to decrease the chance that a cancer will recur
A, Ab
antibody
AG, Ag
antigen
CA, Ca
cancer, carcinoma
CIS
carcinoma in situ
DCIS
ductal carcinoma in situ
HZ
herpes zoster
HL
Hodgkin's lymphoma
IG
immunoglobulin
MET
metastasis
met
metastisize
NHL
non-Hodgkin lymphoma
VSZ
varicella
perietal pericardium
fibrous sac that surrounds and protects the heart
pericardial fluid
fluid between perietal pericardium and visceral pericardium
visceral pericardium
inner layer of pericardium, outer layer of heart
coronary arteries
blood vessels that branch from the aorta and carry oxygen-rich blood to the heart muscle
interventricular septum
partition between the right and left ventricles
pulmonary circulation
flow of blood from the heart to the lungs and back to the heart
systemic circulation
circulation that supplies blood to all the body except to the lungs
sinoatrial node
pacemaker of the heart, located in posterior wall of right atrium near entrance of SVC
atrioventricular node
a node of specialized heart muscle located on floor of right atrium, transmits electral impulses to bundle of His
bundle of His (HISS)
a group of fibers located within the interventricular septum. carry electrical impulses to ensure sequence of heart contractions, travel to right and left ventricles and Purkinje fibres
purkinje fibres
specialized conductive fibres located in walls of ventricles. relay electrical impulses to ventrical cells, causing ventricular contraction
sinus rhythm
normal heart rhythm
P wave
due to stimulation (contraction) of atria
QRS complex
shows the stimulation (contraction) of the ventricles. the atria relax as the ventricles contract
T wave
recovery (relaxation) of ventricles
cartoid arteries
the major arteries that carry blood upward to the head
venae cavae
the two largest veins in the body; return blood into the heart
pulse
Beat of the heart as felt through the walls of the arteries.
systolic pressure
Blood pressure in the arteries during contraction of the ventricles.
diastolic pressure
occurs when the ventricles are relaxed; the lowest pressure against the walls of an artery
plasma
contains nutrients, hormones, waste products. 91% water, 9% proteins (clotting proteins)
serum
plasma fluid after the blood cells and the clotting proteins have been removed
fibrinogen and prothrombin
clotting proteins found in plasma
Neutrophils
most common type of wbc, engulfs invading microbes and contributes to the nonspecific defenses of the body against disease.
basophils
releases histamine, least common type of wbc, can form in red bone marrow
eosinophils
formed in red bone marrow and then migrate to tissues throughout the body, fight parasitic organisms, play major role in allergic reactions
monocyte
formed in red bone marrow, lymph nodes, spleen. fight infections through phagocytosis
vascular surgeon
a physician who specializes in the diagnosis, medical management, and surgical treatment of disorders of the blood vessels
coronary artery disease (CAD)
atherosclerosis of coronary arteries, reduces blood supply to heart, causes insufficient oxygen supply (angina, heart attack, death)
atherosclerosis
hardening and narrowing of the arteries caused by a buildup of cholesterol plaque on the interior walls of the arteries
plaque
A deposit of fatty material on the inner lining of an arterial wall
atheroma
a deposit of plaque on or within the arterial wall