Lecture 7 Glycolysis

Glycolysis is what

Turning glucose into two pyruvate molecules

What’s produced in glycolosis

2 NADH and 4 ATP (net of 2)

electron carriers

NADH to NAD+ (vitamin 3) and FADH to FAD (vitamin 2)

Irreversible reactions

1 , 3 , 10

Reaction 1

Catalyzed by hexokinase. (Glucose + ATP → glucose 6 phosphate + ADP)

Reaction 3

Phosphofructokinase. (Fructose-6-phosphate + ATP → fructose -1,6-biphosphate + adp)

Reaction 10

Pyruvate kinase. (Phosphoenolpyruvate + adp → pyruvate + atp)

Investment phase

1-5. Two G3P’s made. 2 atp used none produced.

Payoff Phase

6-10. 2 pyruvate produced. If oxygen is present sent to mitochondria. Absent: lactase or ethanol fermentation

What are glycolysis pathway

Glucose 6 phosphate glycogen synthesizes Pentose phosphate pathways. G3P synthesize glycolipids. Pyruvate synthesize fatty acids.

Alcohol Fermentation

Pyruvate to intermediate acetaldehyde to alcohol. CO2 produced and NADH recycles to NAD+.

Lactic Fermentation

Lactase converted to pyruvate. NADH recycled to NAD+. Occurs in muscle tissues

Pyruvate oxidation results

Oxygen sent to matrix converted to Acetyl Co A. CO2 produced and removed. NADH recycled too.