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What is the primary function of red blood cells?
Carry oxygen and carbon dioxide
What is the shape of a red blood cell?
Biconcave disc
Which of the following allows RBCs to fit through small capillaries?
Their biconcave shape
How long does a typical red blood cell live?
120 days
Red blood cells use which type of metabolism?
Anaerobic
Hemoglobin is responsible for:
Binding and transporting oxygen
What part of hemoglobin binds to oxygen?
Iron in the heme group
When oxygen binds to hemoglobin, what color does it turn?
Red
The process of red blood cell formation is called:
Erythropoiesis
What hormone signals the production of RBCs?
Erythropoietin
Where is erythropoietin produced?
Kidney
Erythropoiesis primarily occurs in:
Red bone marrow
Which condition triggers EPO release?
Hypoxia (low oxygen)
What is the name of the immature RBC that enters the bloodstream?
Reticulocyte
Where are old RBCs broken down?
Liver, spleen, and bone marrow
What happens to the globin part of hemoglobin during recycling?
Broken into amino acids
What is iron from hemoglobin used for?
Building new hemoglobin
What pigment is formed first from heme breakdown?
Biliverdin
Biliverdin is converted into:
Bilirubin
Jaundice is caused by the accumulation of:
Bilirubin
A blocked bile duct may cause:
Jaundice
Anemia results in:
Reduced oxygen-carrying capacity
Which of the following is a symptom of anemia?
Muscle fatigue
What type of anemia is caused by low iron intake?
Iron-deficiency anemia
Sickle cell anemia is an example of:
Genetic anemia
Pernicious anemia is caused by:
Deficiency of intrinsic factor
Aplastic anemia results from:
Bone marrow failure to produce RBCs
Blood types are determined by:
Antigens on red blood cells
A person with type A blood has:
A antigens only
Type AB blood has:
Both A and B antigens
A person with type O blood has:
No antigens
Rh factor is another name for:
Antigen D
A person with A- blood has:
A antigens, no Rh antigens
What happens in a transfusion reaction?
Antibodies attack foreign RBCs
Which blood type is considered the universal donor?
O–
Which blood type is the universal recipient?
AB+
Why can’t a person with type A blood receive type B blood?
Type A has anti-B antibodies
When do anti-A and anti-B antibodies naturally develop?
Within first 6 months of life
Why does Rh incompatibility in pregnancy affect the second child more than the first?
The mother develops anti-Rh antibodies after the first exposure
Blood typing is important before transfusions because:
It prevents agglutination reactions