infectious diseases (better version)

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1

microscope was developed by:

Leeuwenhock

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2

Penicillin was discovered by:

Fleming

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3

the first vaccine was developed by:

Jenner

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4

Shigella was discovered by:

Kiyoshi Shiga

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5

Serum therapy for tetanus was discovered by:

Kitasato

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6

Noguchi Hideyo discovered:

yellow fever and syphilis

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7

disinfection before and after surgery was promoted by:

Lister

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8

arrange the following from smallest to largest: mycoplasma, rickettsia, chlamydia, coccus, virus, fungi, bacillus.

virus, mycoplasma, chlamydia, rickettsia, coccus, bacillus, fungi

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9

flagella supports ( ) of the bacteria.

movement

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10

the capsule of a bacterium has ( ), which means it is toxic to the human body

virulence

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11

pili are ( ) - like structures on the cell wall of the bacteria

hair

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12

5 clinically important spore-forming bacteria:

bacillus anthracis

bacillus cereus

clostridium tetani

clostridium botulinum

clostridium difficile

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13

gram stain order

crystal violet, iodine, alcohol, safranin

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14

outline the phases of bacteria growth

lag phase, exponential phase, stationary phase, death phase

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15

if bacteria grow only at the top of the test tube, the bacteria species is a…

obligate aerobe

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16

if bacteria grow only at the base of the test tube, the bacteria species is a…

obligate anaerobe

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17

if bacteria are present in both the top and bottom of the test tube, the bacteria species is a…

facultative anaerobe

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18

flu virus is transmitted by….

droplet

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19

HBV is transmitted by…

blood

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20

chickenpox is transmitted by…

aerosols

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21

measles is transmitted by…

aerosols

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22

rubella is transmitted by…

droplet

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23

5causes of opportunistic infections

genetic, chemotherapy, HIV/AIDS, bone marrow disease, pregnancy

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24

outline the process of infection

entry, invasion, multiplication, damage, progression, resolution

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25

3 important airborne diseases

tuberculosis, chickenpox, measles

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26

4 important bloodborne diseases

HIV, HBV, HPV, HTLV-1

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27

5 important fecal-oral diseases

norovirus, HAV, rotavirus, cholera, salmonella

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28

trans-placental diseases

syphilis, toxoplasma, cytomegalovirus, rubella, parvovirus

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29

3 important birth canal-transmitted diseases

HBV, HIV, streptococcus agalactiae

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30

2 important diseases transmitted by breastmilk

HIV, HTLV-1

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31

if a gram-positive coccus is catalase positive, it is….

staphylococcus

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32

if a gram-positive coccus is catalase negative, it is either ( ) or ( )

enterococcus, streptococcus

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33

major risk factor of aspergillus species infections

neutropenia

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34

if a staphylococcus is coagulase positive, it is….

staphylococcus aureus

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35

a ( ) test can identify alpha-hemolytic enterococcus

optohin

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36

a ( ) test can identify beta-hemolytic enterococcus

bacitracin

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37

a ( ) test can identify gamma-hemolytic enterococcus

cAMP

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38

2 important alpha-hemolytic enterococcus

streptococcus pneumoniae, viridans streptococci

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39

2 important beta-hemolytic enterococcus

Streptococcus pyogenes (group a strep), Streptococcus agalactiae (group b strep)

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40

2 important gamma-hemolytic enterococcus

enterococcus faecalis (group d strep), enterococcus faecium

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41

CNS (coagulase negative staphylococcus) has ( ) virulence

low

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42

staphylococcus is ( ) hemolytic

beta

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43

staphylococcus aureus releases ( ) which causes food poisoning

enterotoxin

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44

staphylococcus aureus can be either ( ) resistant or sensitive, and classified as MRSA and MSSA.

methicilin

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45

E.coli can ferment ( )

lactose

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46

endotoxin is specific to gram ( ) bacteria, and has ( ) virulence.

negative, low

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47

exotoxin is specific to gram ( ) bacteria, and has ( ) virulence

positive, high

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48

endotoxin causes ( ) symtpoms

general

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49

exotoxin causes ( ) symtpoms

specific

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50

TB can live inside ( ) after phagocytosis.

macrophages

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51

mycobacteria are classified as…

acid-fast bacilli

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52

3 atypical bacteria?

mycoplasma, chlamydia, legionella

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53

3 similarities of all atypical bacteria

can’t identify using gram stain

causes atypical pneumonia

all parasitic

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54

mycoplasma pneumoniae causes

pneumonia

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55

mycoplasma hominis causes

urogenital infection

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56

mycoplasma genitalium causes

urogenital infections and STI

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57

chlamydia trachomatis causes

STI

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58

chlamydia pneumoniae causes

pneumonia

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59

chlamydia psitacci is inhaled from

bird poop

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60

legionella causes

pneumonia

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61

2 methods to test sensitivity of a drug in a bacteria culture

disk and dilution

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62

3 ranks of sensitivity of a drug

S (suseptible), I (intermediate), R (resistant)

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63

3 pathogens of typical pneumonia (with gram stain findings and capsule)

streptococcus pneumoniae (gram positive streptococcus with capsule)

haemophilus influenzae (gram negative coccus with capsule)

moraxella catarrhalis (gram negative coccus without capsule)

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64

the lipopolysaccharide capsule can be toxic to those with no or dysfunctional ( )

spleen

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65

what drug is used to treat typical pneumonia?

ceftriaxone

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66

the most virulent viruses are ( ).

non-enveloped

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67

the only ssDNA virus is…

parvovirus

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68

the only dsRNA virus is…

reovirus

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69

gram stain findings of gonorrhea

gram negative coccus

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70

gonorrhea causes…

urethritis and abnormal genital discharge

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71

structure of treponema pallidum?

spirochete

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72

triponema pallidum cases…

syphilis (genital ulcers)

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73

effect of HPV on the genitals

genital warts

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74

retroviruses can be differentiated into…

oncoviridae and entiviridae

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75

most important oncoviridae

HTLV-1

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76

most important entiviridae

HIV

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77

5 clinical signs of immunocompromised HIV infections. (AIDS-defining illnesses)

oral candidiasis, candida esophagitis, herpes zoster, cytomegalovirus retinitis, toxoplasmic encephalitis

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78

3 pathogens for bacterial meningitis (with gram stain findings and capsule)

streptococcus pneumoniae (gram-positive streptococcus with capsule), haemophilus influenzae (gram-negative coccus with capsule), neisseria meningitis (gram-negative coccus with capsule)

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79

2 meningial signs

kernig and bruzinski

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80

3 analyses (tests) for meningitis

blood culture

cerebrospinal fluid test

cerebrospinal fluid culture

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81

3 important gram-negative pathogens for blood stream infections

E. coli, proteus mirabilis, klebsiella pneumoniae

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82

what types of gram-positive cocci can cause blood stream infections?

staphylococcus aureus, streptococci, enterococci

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83

infective endocarditis can cause ( ) in the heart, and is often caused by ( ).

vegetation, viridans streptococcus

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84

prostatitis is often caused by ( )

enterococcus

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85

pneumonia is the infection of the ( )

alveoli

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86

pneumonitis is the infection of the ( )

interstitial tissue

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87

3 pathogens causing neonatal meningitis

E. coli, streptococcus agalactiae, listeria monocytogenes

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88

3 pathogens causing infant/toddler meningitis (~5yo)

streptococcus pneumoniae, haemophilus influenza type B, neisseria meningitidis

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89

2 pathogens causing child/adolescent/adult meningitis (6~50 yo)

streptococcus pneumoniae, neisseria meningitidis

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90

3 pathogens causing geriatric meningitis

streptococcus pneumoniae, neisseria meningitidis, listeria monocytogenes

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91

most important pathogen of viral meningitis

herpes

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92

most important pathogen of fungal meningitis

cryptococcus neoformans

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93

HAV and HEV cause ( ) hepatitis and transmitted by ( )

acute, fecal-oral

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94

HBV and HCV cause ( ) hepatitis and transmitted by ( )

chronic, blood

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95

what two hepatitis viruses cause cancer?

HBV and HCV

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96

yellow fever can cause ( ), and patients often present with jaundice.

hepatitis

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97

malaria is caused by a parasite called…

plasmodium

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98

which species of plasmodium causes the most severe form of malaria?

P. falciparum

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99

a characteristic symptom of malaria is ( ) stages.

hot and cold

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100

dengue is caused by a ( ) carried by mosquitoes

virus

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