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What is this?
-very small (.025-.35 um)
-usually round shape
-genome protein capsule "capsid"
-can be enveloped or not
Virus
T/F: viruses are capable of replicating without a host
False! Viruses MUST have a host to be able to replicate
How does canine parvovirus type 2 spread?
Direct dog-to-dog contact, contaminated feces, environments or people
What are some symptoms of canine parvovirus type 2?
Loss of appetite, vomiting, diarrhea (might be bloody) and dehydration
Is canine parvovirus type 2 environmentally stable?
Yes, it can remain infectious for at least a year in the soil
What type of virus is feline leukemia virus?
An oncogenic, enveloped, immunosuppressive lentivirus
What is the most common infectious disease in cats?
feline leukemia virus
How is feline leukemia virus shed?
saliva, nasal secretions, urine, feces, milk
T/F: vertical transmission can occur before they are born and while nursing for feline leukemia virus
True
What is the most common viral disease in cattle?
Bovine viral diarrheal virus
What is this?
-single cell organisms
-usually 10-100 times larger than viruses
-sphere or rod shaped
-reproduce on their own
-move with flagella or gliding
Bacteria
What has a thick peptidoglycan later and no outer lipid membrane, staining purple-blue?
Gram positive bacteria
What is erysipelothrix rhusiopathiae?
-Gram positive rod shaped bacterium in swine
-leaves red diamond shaped patches
-zoonotic
What has a thin peptidoglycan layer with an outer lipid membrane that stains red-pink?
Gram negative bacteria
What is this?
-eukaryote (cells have a nucleus)
-can replicate in host or freely in the environment
Parasites
What are ascaris suum?
-large roundworm in pigs
-zoonotic
Is ascaris suum environmentally stable?
Very, can live in soil for up to 10 years
What is this?
-eukaryote (nuclei and vacuoles)
-largest of all pathogen types: many shapes
-mostly found as environmentally resistant spores and molds
Fungi
What is this?
-a misfolded protein that can trigger normal proteins in the brain to fold abnormally
Prion
What is : prevent unintentional contamination and foodborn illnesses
Food safety
What is: protect food from intentional contamination to cause harm or economic disruption
Food defense
What is: access to safe and nutritious food
Food security
What is: all necessary actions to keep food safe, prevent contamination and ensure quality
Food protection
What two things make up food protection?
Food safety and food defense
What does farm to fork mean?
Describes the entire food production process from growing/raising food on a farm to it ending up on your plate
Who might have these responsibilities?
-animal health and welfare
-disease prevention
-food safety
-public health
-regulatory oversight
-research and development
Food supply veterinarians
Who is in charge of shell eggs food safety?
FDA
Who is in charge of egg products food safety?
USDA
What is foodborne illness?
Comes from eating contaminated food, can be caused by microorganisms, chemical adulterants or toxins
Who is affected by campylobacteriosis?
Kittens, puppies, poultry, livestock and unpasteurized milk
Who is affected by cryptosporidiosis?
Calves, goat kids and lambs
Who is affected by escherichia coli?
Cattle, goats, sheep, and unpasteurized milk
Who is affected by salmonellosis?
Reptiles, baby chicks and ducklings, adult poultry, livestock, dogs, cats and unpasteurized milk
Who is affected by listeria?
Ruminants, rodents, dogs, cats, and birds, soil, water, silage, milk, cheese, feces, sewage and foodstuffs
What is a common waterborne illness?
Crypto
How is crypto passed?
Stool of infected person or animal
How is salmonella normally transmitted?
To humans by eating foods contaminated with animal feces
__________ are less resistant to disinfectants because their lips layer is easily disrupted
enveloped viruses
what is caseous lymphadenitis?
Cornebacterium pseudotuberculosis
what type of bacteria is caseous lymphadenitis?
gram positive, facultative intracellular coccobacillus
how does caseous lmyphadenitis present?
abscess formation in or near major peripheral lymph node or within internal organs and lymph nodes
what is the environmental stability of caseous lymphadenitis?
incubation period is 1-3 months, can survive on fomites such as bedding and wood for 2 months and in soil for 8 months
is caseous lymphadenitis zoonotic?
yes
T/F: no intramammary antimicrobials are currently labeled for the treatment of Klesiebella pneumonia mastitis infections in the USA
true
is klebsiella pneumonia mastitis zoonotic?
yes
what symptoms might a heavily infected pig have with ascaris suum?
-difficulty breathing, "thumps"
-weight gain
-unthrifty
-slow weight gain
-whole worms in manure
what is dermatophytosis?
hair or wool loss caused by trichophton or mycrosporum genera fungi
when do clinical signs begin to show for dermatophytosis?
4-14 days after exposure
what does dermatophytosis look like?
multiple areas can be affected at a given time, usually circular in outline and slightly raised, size of lesions are variable but can become very extensive
what is the fatal form of aspergillus?
systemic infection spreads beyond the lungs to other organs
how does aspergillus normally present?
chronic nasal discharge that often has strong odor, lasts for weeks to months does not respond to antibiotics or other common therapies, typically involves only one nostril
-many drugs traditionally used to treat have toxic side effects
is aspergillus zoonotic?
no
is dermatophytosis zoonotic?
yes
what is chronic wasting disease?
prion disease in deer and elk
how does chronic wasting disease present?
drastic weight loss, stumbling listlessness, lack of coordination, drooling and excessive thirst or urination
how is chronic wasting disease spread?
spread among cervids through environmental contamination, no vaccine or treatment
T/F: cooking temperatures are able to disable CWB prions
false, it has been found that cwd cannot be gotten rid of in meat
what causes colibacillosis? what does it look like?
-caused by numerous bacterial strains of escherichia coli
-gram negative flagellated bacilli (rod shape)
what are some virulence factors of colibacillosis?
-encapsulated
-fimbriae
-easily adheres to mucosal enterocyte receptors within small intestine
-rapid colonization
-certain strains produce entertoxins
-fecal oral route
why is it hard to treat colibacillosis?
-resistant to widespread of disinfectants as well as antibiotics
-lack of effective vaccines because there is constant mutation
what are the clinical signs of colibacillosis in swine?
anorexia and weight loss, asthenia, cyanosis, non-odorous non-bloody diarrhea, edema, fever, hemorrhage, paralysis and sudden death
what are the clinical signs of colibacillosis in poultry?
respiratory distress, anorexia, diarrhea, weight loss, poor growth and sudden death
Is colibacillosis zoonotic?
yes, food borne transmission
what is the most common systemic fungal disease found in cats?
cryptococcus neoformans
what is cryptococcus neoformans?
airborne pathogen caused by inhalation of microscopic fungi from environment, found in soil, decaying wood and bird dropping
what are the clinical signs of cryptococcus neoformans?
cutaneous lesions of the nose, mucous nasal discharge, weight loss and inappetence, lethargy, joint inflammation and neurological symptoms
what is porcine epidemic diarrhea virus?
enveloped 95-190 nm with single stranded positive-sense RNA genome
how is porcine epidemic virus spread?
-fecal oral route
-fecal nasal route
-fomites
-vertical transmission
-sexual intercourse
T/F: porcine epidemic diarrhea virus has a high mortality in neonatal pig and low mortality in post weaned animals
true
what is tritrichomonas foetus?
parasite causing venereal disease in cattle
how is transmission increased for tritrichomonas foetus?
-not checking to see if bull/cow has before breeding
-when an infected bull breeds a cow natrually, approximately 30-90% of those cows become infected
-not treating infected cattle
-a lack of biosecurity protocols
-commingling of breeding groups
what is the most common side of tritrichomonas foetus?
heifers and cows have reproductive failure as a result of early embryonic death
what is the hotspot matrix?
how environmental stability and zoonotic risk cause a disease
what is the x-axis for the hotspot matrix?
environmental stability
what is the y-axis of hotspot matrix?
zoonotic risk (high to low)
What do Veterinary Medical Officers (VMOs) conduct?
carcass inspections
who regulates meat, poultry and egg production?
USDA-FSIS
who focuses on animal health and "pre-harvest"?
USDA-APHIS
who regulates pet food?
FDA
who regulates seafood, produce, dairy?
FDA
who oversees drug residues/approvals?
FDA
who primarily investigates food borne illness outbreaks at the retail/restaurant level
state and local health departments
Who regulates more than 80% of the US food supply?
FDA
Who enforces primary through physical inspections?
FSIS
who regulated livestock feed additives?
FDA
Who am I? I conduct antemortem inspections of swine before they are slaughtered
FSIS Veterinary Medical Officer
Who am I ? I educate dairy producers about accurate drug withdrawal times and recordkeeping to prevent violation of drug residues in milk
food animal veterinarian
Who am I? I visit dairy producers to discuss drug withdrawal times and recordkeeping to prevent violation of drug residues in milk
FDA Veterinary Medical Officer
Who am I? I work with producers to ensure that cull dairy cows are fit for transport to a slaughter facility
food animal veterinarian
Who am I ? I conduct TB testing in cattle
initial test=food animal veterinarian
secondary test after postive= APHIS Veterinary Medical Officer
Who am I? I establish a VCPR with producers in order to prescribe antimicrobials in feed and or water
food supply veterinarian
Who am I? I inspect meat, poultry and eggs imported from other countries
FSIS Veterinary Medical Officer
What stage of food production is this? Activities before products is ready to be sold
pre-harvest
What stage of food production is this? Transformation of raw products into food
processing
What stage of food production is this? preparation of the product for storage processing: cleaning, cooling and packaging
post-harvest
what are the sources of pathogens?
-personnel
-vectors
-rodents
-insects
-birds
-feed
-water
-compost
Define: proper handling, nutrition, and environment to minimize stress
animal welfare
define: preventing chemical residues, contaminants and physical hazards from entering the food supply
food safety
define: maintaining documentation for animal health and movement
traceability and record-keeping
define: implementing measures to prevent the spread of diseases
biosecurity