PMC ll- Exam1: MedChem of Anxiolytics-Cox

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19 Terms

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GABA (a) Receptor

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<p></p>

Alprazolam (Xanax) - Ring-fused BZDs for anxiety and sedation

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Midazolam (Versed) - Ring-fused BZDs for anxiety and sedation

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Chlordiazepoxide (Librium) - Long Lasting 1st gen

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Diazepam (Valium) - Long Lasting 1st gen

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Lorazepam (Ativan) - Shorter action hydroxylated

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Oxazepam (Serax) - Shorter acting hydroxylate

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Clobazam - BZDs Also used in seizures

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Clonazepam (klonopin) - BZDs also used in seizures

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Clorazepate (Traxene) - BZDs also used in seizures

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Estazolam - BZDs used as hypnotics

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Flurazepam (Dlamane) - BZDs used as hypnotics

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Quazepam (Doral) - BZDs used as hypnotics

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Temazepam (Restoril) - BZDs used as hypnotics

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Triazolam (Halclon) - BZDs used as hypnotics

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General Structure of the BZDs - 5-phenyl-1,4-benzodiazepine

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<p>what’s the metabolism and which phase is shown in this figured?</p>

what’s the metabolism and which phase is shown in this figured?

Glucuronidation, Phase 2

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Eszopiclon (Lunesta) - (S) isomer of Zopiclone

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Zolpidem (Ambien)