PMC ll- Exam1: MedChem of Anxiolytics-Cox
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19 Terms
GABA (a) Receptor
Alprazolam (Xanax) - Ring-fused BZDs for anxiety and sedation
Midazolam (Versed) - Ring-fused BZDs for anxiety and sedation
Chlordiazepoxide (Librium) - Long Lasting 1st gen
Diazepam (Valium) - Long Lasting 1st gen
Lorazepam (Ativan) - Shorter action hydroxylated
Oxazepam (Serax) - Shorter acting hydroxylate
Clobazam - BZDs Also used in seizures
Clonazepam (klonopin) - BZDs also used in seizures
Clorazepate (Traxene) - BZDs also used in seizures
Estazolam - BZDs used as hypnotics
Flurazepam (Dlamane) - BZDs used as hypnotics
Quazepam (Doral) - BZDs used as hypnotics
Temazepam (Restoril) - BZDs used as hypnotics
Triazolam (Halclon) - BZDs used as hypnotics
General Structure of the BZDs - 5-phenyl-1,4-benzodiazepine
what’s the metabolism and which phase is shown in this figured?
Glucuronidation, Phase 2
Eszopiclon (Lunesta) - (S) isomer of Zopiclone
Zolpidem (Ambien)
Note 
Flashcards (76)